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Pascal Reynier

Pascal Reynier

D-Index & Metrics

Molecular Biology

D-Index
72
Citations
17459
World Ranking
1324
National Ranking
42

Overview

Pascal Reynier is affiliated with the University of Angers in France. Their research spans multiple areas in medicine and biochemistry, with a strong focus on mitochondrial biology and metabolic disorders. Reynier has contributed extensively to the understanding of mitochondrial function and pathology, which is reflected in numerous published works and collaborations.

Their recent publications include:

  • "Mitochondria: their role in spermatozoa and in male infertility" (2021) published in Human Reproduction Update
  • "Dominant optic atrophy: Culprit mitochondria in the optic nerve" (2020) published in Progress in Retinal and Eye Research
  • "Embryo and Its Mitochondria" (2021) published in Antioxidants
  • "High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts" (2021) published in EMBO Molecular Medicine
  • "Long-Term Efficacy and Safety of Once-Weekly Semaglutide for Weight Loss in Patients Without Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials" (2024) published in The American Journal of Cardiology

Reynier frequently collaborates with other researchers, including:

  • Kristian B. Filion
  • Juan Manuel Chao de la Barca
  • Delphine Mirebeau-Prunier
  • Guy Lenaers
  • Vincent Procaccio

Their scientific contributions are found across various publication venues, with multiple articles appearing in:

  • Journal of Clinical Medicine
  • Scientific Reports
  • Biomedicines
  • Antioxidants
  • CMAJ Open

Reynier's main fields of study include Medicine as well as Biochemistry, Genetics, and Molecular Biology. Within these fields, the scientist's subfields of interest are Molecular Biology, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Physiology, and Public Health, Environmental and Occupational Health.

The primary topics covered in Reynier's research involve an array of biochemical and clinical concerns, such as:

  • Mitochondrial Function and Pathology
  • Metabolism and Genetic Disorders
  • Metabolomics and Mass Spectrometry Studies
  • ATP Synthase and ATPases Research
  • Pregnancy and Preeclampsia Studies
  • Diabetes Treatment and Management
  • Autophagy in Disease and Therapy

Best Publications

  • Mitochondrial DNA content affects the fertilizability of human oocytes.

    P Reynier;P May-Panloup;M F Chrétien;C J Morgan

  • OPA1 mutations induce mitochondrial DNA instability and optic atrophy plus phenotypes

    Patrizia Amati-Bonneau;Maria Lucia Valentino;Pascal Reynier;Maria Esther Gallardo

  • Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: a novel disorder of mtDNA maintenance.

    Gavin Hudson;Patrizia Amati-Bonneau;Emma L. Blakely;Joanna D. Stewart

  • Multi-system neurological disease is common in patients with OPA1 mutations

    Patrick Yu-Wai-Man;Philip G. Griffiths;Philip G. Griffiths;G. Gorman;C.-M. Lourenco

  • Resveratrol Induces a Mitochondrial Complex I-dependent Increase in NADH Oxidation Responsible for Sirtuin Activation in Liver Cells

    Valérie Desquiret-Dumas;Valérie Desquiret-Dumas;Naïg Gueguen;Naïg Gueguen;Géraldine Leman;Géraldine Leman;Stéphanie Baron

  • Ovarian ageing: the role of mitochondria in oocytes and follicles

    Pascale May-Panloup;Lisa Boucret;Juan Manuel Chao de la Barca;Valérie Desquiret-Dumas

  • Low oocyte mitochondrial DNA content in ovarian insufficiency

    P. May-Panloup;M.F. Chrétien;C. Jacques;C. Vasseur

  • Dominant optic atrophy

    Guy Lenaers;Christian P Hamel;Cecile Delettre;Patrizia Amati-Bonneau;Patrizia Amati-Bonneau

  • Mitochondrial dynamics and disease, OPA1.

    Aurélien Olichon;Emmanuelle Guillou;Cécile Delettre;Thomas Landes

  • OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution.

    Ghizlane Elachouri;Sara Vidoni;Claudia Zanna;Alexandre Pattyn

  • Mitochondrial DNA in the oocyte and the developing embryo.

    Pascale May-Panloup;Marie-Françoise Chretien;Yves Malthiery;Pascal Reynier

  • Increased sperm mitochondrial DNA content in male infertility

    May-Panloup P;Chrétien Mf;Savagner F;Vasseur C

  • Increase of mitochondrial DNA content and transcripts in early bovine embryogenesis associated with upregulation of mtTFA and NRF1 transcription factors.

    Pascale May-Panloup;Xavier Vignon;Marie-Françoise Chrétien;Yvan Heyman

  • Adenine nucleotide translocase 2 is a key mitochondrial protein in cancer metabolism

    Arnaud Chevrollier;Dominique Loiseau;Pascal Reynier;Georges Stepien

  • OPA1 R445H mutation in optic atrophy associated with sensorineural deafness

    Patrizia Amati-Bonneau;Agnès Guichet;Aurélien Olichon;Arnaud Chevrollier

  • Mitochondrial coupling defect in Charcot-Marie-Tooth type 2A disease.

    Dominique Loiseau;Arnaud Chevrollier;Christophe Verny;Virginie Guillet

  • Effects of OPA1 mutations on mitochondrial morphology and apoptosis: relevance to ADOA pathogenesis.

    Aurélien Olichon;Thomas Landes;Laetitia Arnauné-Pelloquin;Laurent J. Emorine

  • Low serum testosterone assayed by liquid chromatography-tandem mass spectrometry. Comparison with five immunoassay techniques.

    Valérie Moal;Elisabeth Mathieu;Pascal Reynier;Yves Malthièry

  • Impact of various handling and storage conditions on quantitative detection of hepatitis C virus RNA

    Philippe Halfon;Hacène Khiri;Victoria Gérolami;Marc Bourlière

  • OPA3 gene mutations responsible for autosomal dominant optic atrophy and cataract

    P Reynier;P Amati-Bonneau;C Verny;A Olichon

Frequent Co-Authors

Dominique Bonneau
Dominique Bonneau University of Angers
Vincent Procaccio
Vincent Procaccio University of Angers
Guy Lenaers
Guy Lenaers University of Angers
Daniel Henrion
Daniel Henrion University of Angers
Valerio Carelli
Valerio Carelli University of Bologna
Josseline Kaplan
Josseline Kaplan Université Paris Cité
Jean-Michel Rozet
Jean-Michel Rozet Université Paris Cité
Bernd Wissinger
Bernd Wissinger University of Tübingen
Hélène Dollfus
Hélène Dollfus University of Strasbourg

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