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Vincent Procaccio

Vincent Procaccio

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Genetics
France
2024

D-Index & Metrics

Genetics

D-Index
70
Citations
18451
World Ranking
2272
National Ranking
107

Research.com Recognitions

  • 2024 - Research.com Genetics in France Leader Award

Overview

Vincent Procaccio is affiliated with the University of Angers in France. Their research primarily centers on biochemistry, genetics, and molecular biology, with a significant focus on medicine. Their work spans several subfields including molecular biology, clinical biochemistry, genetics, physiology, and epidemiology.

A major area of interest in their research involves mitochondrial function and pathology. Other key topics include metabolism and genetic disorders, genomics and rare diseases, ATP synthase and ATPases research, genetics and neurodevelopmental disorders, genetics related to aging and longevity in model organisms, and research on Trypanosoma species and its wider implications.

The scientist has contributed to numerous publications in prominent venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Human Mutation, Brain Communications, and Scientific Data. Their recent papers include:

  • Specifications of the ACMG/AMP standards and guidelines for mitochondrial DNA variant interpretation (2020, Human Mutation)
  • OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases (2023, Communications Biology)
  • Lactic Acidosis Together with GM-CSF and M-CSF Induces Human Macrophages toward an Inflammatory Protumor Phenotype (2020, Cancer Immunology Research)
  • Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging (2023, Psychoneuroendocrinology)
  • Co-Exposure of Cardiomyocytes to IFN-γ and TNF-α Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the Pathogenesis of Chronic Chagas Disease Cardiomyopathy (2021, Frontiers in Immunology)

Throughout their career, Vincent Procaccio has frequently collaborated with several researchers, including:

  • Céline Bris
  • Guy Lenaers
  • Pascal Reynier
  • Dominique Bonneau
  • Valérie Desquiret-Dumas

Best Publications

  • Effects of Purifying and Adaptive Selection on Regional Variation in Human mtDNA

    Eduardo Ruiz-Pesini;Dan Mishmar;Martin Brandon;Vincent Procaccio

  • Mitochondrial Energetics and Therapeutics

    Douglas C. Wallace;Weiwei Fan;Vincent Procaccio

  • An enhanced MITOMAP with a global mtDNA mutational phylogeny.

    Eduardo Ruiz-Pesini;Marie T. Lott;Vincent Procaccio;Jason C. Poole

  • BDNF val66met polymorphism is associated with modified experience-dependent plasticity in human motor cortex

    Jeffrey A Kleim;Sheila Chan;Erin Pringle;Kellan Schallert

  • Malignant-Hyperthermia Susceptibility Is Associated with a Mutation of the a1-Subunit of the Human Dihydropyridine-Sensitive L-Type Voltage-Dependent Calcium-Channel Receptor in Skeletal Muscle

    Nicole Monnier;Vincent Procaccio;Paul Stieglitz;Joël. Lunardi

  • mtDNA Variation and Analysis Using Mitomap and Mitomaster

    Marie T. Lott;Jeremy N. Leipzig;Olga Derbeneva;H. Michael Xie

  • Resveratrol Induces a Mitochondrial Complex I-dependent Increase in NADH Oxidation Responsible for Sirtuin Activation in Liver Cells

    Valérie Desquiret-Dumas;Valérie Desquiret-Dumas;Naïg Gueguen;Naïg Gueguen;Géraldine Leman;Géraldine Leman;Stéphanie Baron

  • Ovarian ageing: the role of mitochondria in oocytes and follicles

    Pascale May-Panloup;Lisa Boucret;Juan Manuel Chao de la Barca;Valérie Desquiret-Dumas

  • Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity.

    Lydia W. S. Finley;Wilhelm Haas;Valérie Desquiret-Dumas;Douglas C. Wallace

  • Estrogen Increases Mitochondrial Efficiency and Reduces Oxidative Stress in Cerebral Blood Vessels

    Chris Stirone;Sue P. Duckles;Diana N. Krause;Vincent Procaccio

  • Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming

    Martin Picard;Jiangwen Zhang;Saege Hancock;Olga Derbeneva

  • Dominant optic atrophy

    Guy Lenaers;Christian P Hamel;Cecile Delettre;Patrizia Amati-Bonneau;Patrizia Amati-Bonneau

  • Two‐dimensional electrophoresis of human placental mitochondria and protein identification by mass spectrometry: Toward a human mitochondrial proteome

    Thierry Rabilloud;Sylvie Kieffer;Vincent Procaccio;Mathilde Louwagie

  • BDNF Val66Met Polymorphism Influences Motor System Function in the Human Brain

    Stephanie A. McHughen;Paul F. Rodriguez;Jeffrey A. Kleim;Erin D. Kleim

  • Friedreich ataxia: the oxidative stress paradox

    Hervé Seznec;Delphine Simon;Cécile Bouton;Laurence Reutenauer

  • Estrogen suppresses brain mitochondrial oxidative stress in female and male rats.

    Ali Razmara;Sue P. Duckles;Diana N. Krause;Vincent Procaccio

  • AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders

    Vincenzo Salpietro;Vincenzo Salpietro;Vincenzo Salpietro;Christine L Dixon;Hui Guo;Hui Guo;Oscar D Bello

  • The MFN2 gene is responsible for mitochondrial DNA instability and optic atrophy ‘plus’ phenotype

    Cécile Rouzier;Sylvie Bannwarth;Annabelle Chaussenot;Arnaud Chevrollier

  • Molecular screening of 980 cases of suspected hereditary optic neuropathy with a report on 77 novel OPA1 mutations

    Marc Ferré;Marc Ferré;Dominique Bonneau;Dominique Bonneau;Dan Milea;Dan Milea;Arnaud Chevrollier

  • Mitochondrial Effects of Estrogen Are Mediated by Estrogen Receptor α in Brain Endothelial Cells

    Ali Razmara;Lorraine Sunday;Chris Stirone;Xiao Bo Wang

Frequent Co-Authors

Pascal Reynier
Pascal Reynier University of Angers
Dominique Bonneau
Dominique Bonneau University of Angers
Guy Lenaers
Guy Lenaers University of Angers
Douglas C. Wallace
Douglas C. Wallace Children's Hospital of Philadelphia
Daniel Henrion
Daniel Henrion University of Angers
Marie T. Lott
Marie T. Lott Children's Hospital of Philadelphia
Joël Lunardi
Joël Lunardi Grenoble Alpes University
Josseline Kaplan
Josseline Kaplan Université Paris Cité
Steven C. Cramer
Steven C. Cramer University of California, Los Angeles

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