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Eduardo Ruiz-Pesini

Eduardo Ruiz-Pesini

D-Index & Metrics

Molecular Biology

D-Index
45
Citations
11435
World Ranking
2837
National Ranking
46

Overview

Eduardo Ruiz-Pesini is affiliated with the University of Zaragoza in Spain and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, with additional work in medicine. Their research mainly focuses on mitochondrial function and pathology, metabolism and genetic disorders, ATP synthase and ATPases research, genetics and neurodevelopmental disorders, RNA modifications and cancer, GDF15 and related biomarkers, as well as cancer, hypoxia, and metabolism.

Recent publications highlight a range of topics within these domains. These include:

  • Growth Differentiation Factor 15 is a potential biomarker of therapeutic response for TK2 deficient myopathy (2020, Scientific Reports)
  • Down syndrome is an oxidative phosphorylation disorder (2021, Redox Biology)
  • Oxidative phosphorylation system and cell culture media (2021, Trends in Cell Biology)
  • The Genetic Landscape of Mitochondrial Diseases in Spain: A Nationwide Call (2021, Genes)
  • Oxidative Phosphorylation Dysfunction Modifies the Cell Secretome (2020, International Journal of Molecular Sciences)

The scientist collaborates frequently with several coauthors, including Julio Montoya, M. Pilar Bayona-Bafaluy, Sonia Emperador, Rafael Artuch, and Ester López-Gallardo. These collaborations have contributed to a breadth of publications and further development in related research areas.

Their work has been published predominantly in journals such as Genes, International Journal of Molecular Sciences, Clinical Genetics, Orphanet Journal of Rare Diseases, and Journal of Assisted Reproduction and Genetics. This distribution reflects a specialization in genetic studies and clinical biochemical research.

Eduardo Ruiz-Pesini's research spans multiple subfields including molecular biology, clinical biochemistry, genetics, rheumatology, and public health, environmental and occupational health. This interdisciplinary approach supports a broad investigation into cellular and molecular mechanisms underpinning disease, with a notable focus on mitochondrial biology.

Best Publications

  • Natural selection shaped regional mtDNA variation in humans

    Dan Mishmar;Eduardo Ruiz-Pesini;Pawel Golik;Vincent Macaulay

  • mtDNA mutations increase tumorigenicity in prostate cancer

    John A. Petros;Amanda K. Baumann;Eduardo Ruiz-Pesini;Mahul B. Amin

  • Effects of Purifying and Adaptive Selection on Regional Variation in Human mtDNA

    Eduardo Ruiz-Pesini;Dan Mishmar;Martin Brandon;Vincent Procaccio

  • An enhanced MITOMAP with a global mtDNA mutational phylogeny.

    Eduardo Ruiz-Pesini;Marie T. Lott;Vincent Procaccio;Jason C. Poole

  • Human mtDNA Haplogroups Associated with High or Reduced Spermatozoa Motility

    Eduardo Ruiz-Pesini;Ana-Cristina Lapeña;Carmen Díez-Sánchez;Acisclo Pérez-Martos

  • Correlation of sperm motility with mitochondrial enzymatic activities

    Eduardo Ruiz-Pesini;Carmen Diez;Ana Cristina Lapeña;Acisclo Pérez-Martos

  • Unmasking the causes of multifactorial disorders: OXPHOS differences between mitochondrial haplogroups

    Aurora Gómez-Durán;David Pacheu-Grau;Ester López-Gallardo;Carmen Díez-Sánchez

  • Mitochondrial DNA Diversity in Indigenous Populations of the Southern Extent of Siberia, and the Origins of Native American Haplogroups

    Elena B. Starikovskaya;Rem I. Sukernik;Olga A. Derbeneva;Olga A. Derbeneva;Natalia V. Volodko

  • Evidence for adaptive selection acting on the tRNA and rRNA genes of human mitochondrial DNA.

    Eduardo Ruiz-Pesini;Douglas C. Wallace

  • The role of the mitochondrion in sperm function: is there a place for oxidative phosphorylation or is this a purely glycolytic process?

    Eduardo Ruiz-Pesini;Carmen Díez-Sánchez;Manuel José López-Pérez;José Antonio Enríquez

  • Mitochondrial DNA background modulates the assembly kinetics of OXPHOS complexes in a cellular model of mitochondrial disease.

    Rosa Pello;Miguel A. Martín;Valerio Carelli;Leo G. Nijtmans

  • Mitochondrial DNA-like sequences in the nucleus (NUMTs): insights into our African origins and the mechanism of foreign DNA integration.

    Dan Mishmar;Eduardo Ruiz-Pesini;Martin Brandon;Douglas C. Wallace

  • GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfunction.

    Raquel Montero;Delia Yubero;Delia Yubero;Joan Villarroya;Desiree Henares

  • Transcriptomic profiling of TK2 deficient human skeletal muscle suggests a role for the p53 signalling pathway and identifies growth and differentiation factor-15 as a potential novel biomarker for mitochondrial myopathies

    Susana Graciela Kalko;Sonia Paco;Cristina Jou;Maria Angels Rodríguez

  • Control region mtDNA variants: Longevity, climatic adaptation, and a forensic conundrum

    Pinar E. Coskun;Eduardo Ruiz-Pesini;Douglas C. Wallace

  • A mitochondrial etiology of neurodegenerative diseases: evidence from Parkinson's disease.

    Elza Khusnutdinova;Irina Gilyazova;Eduardo Ruiz-Pesini;Eduardo Ruiz-Pesini;Olga Derbeneva

  • Mitochondrial DNA content of human spermatozoa

    Carmen Díez-Sánchez;Eduardo Ruiz-Pesini;Ana Cristina Lapeña;Julio Montoya

  • Human mitochondrial haplogroup H: the highest VO2max consumer--is it a paradox?

    Diana Martínez-Redondo;Ana Marcuello;José A. Casajús;Ignacio Ara

  • Differences of sperm motility in mitochondrial DNA haplogroup U sublineages.

    Francisco Montiel-Sosa;Eduardo Ruiz-Pesini;Eduardo Ruiz-Pesini;José Antonio Enríquez;Ana Marcuello

  • mtDNA variation, climatic adaptation, degenerative diseases, and longevity.

    D.C. Wallace;E. Ruiz-Pesini;D. Mishmar

Frequent Co-Authors

Julio Montoya
Julio Montoya University of Zaragoza
Rafael Artuch
Rafael Artuch Instituto de Salud Carlos III
José Antonio Enríquez
José Antonio Enríquez Spanish National Centre for Cardiovascular Research
Douglas C. Wallace
Douglas C. Wallace Children's Hospital of Philadelphia
Plácido Navas
Plácido Navas Pablo de Olavide University
Francesc Villarroya
Francesc Villarroya University of Barcelona
Antoni L. Andreu
Antoni L. Andreu Autonomous University of Barcelona
David R. Thorburn
David R. Thorburn Murdoch Children's Research Institute
Robert W. Taylor
Robert W. Taylor Newcastle University
Stephen J. O'Brien
Stephen J. O'Brien Nova Southeastern University

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