D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 89 Citations 31,335 184 World Ranking 451 National Ranking 39

Research.com Recognitions

Awards & Achievements

2005 - Fellow of the American Association for the Advancement of Science (AAAS)

2003 - Fellow of the Royal Society of Edinburgh

2001 - Nobel Prize for their discoveries of key regulators of the cell cycle

1999 - Member of the National Academy of Sciences

1998 - Member of Academia Europaea

1991 - Fellow of the Royal Society, United Kingdom

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Tim Hunt mostly deals with Molecular biology, Cell biology, Biochemistry, Cyclin A and Protein biosynthesis. His Molecular biology study combines topics in areas such as Maturation promoting factor, Messenger RNA and Cyclin B1. His studies deal with areas such as Cyclin-dependent kinase, Anaphase and Cyclin as well as Cell biology.

The various areas that Tim Hunt examines in his Cyclin A study include Cyclin-dependent kinase complex, Cyclin A2 and Cyclin D. His Cyclin D study integrates concerns from other disciplines, such as Cyclin E and Cyclin B. His Protein biosynthesis research is multidisciplinary, incorporating elements of RNA, Reticulocyte, Sea urchin and Cyclin Gene.

His most cited work include:

  • A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. (1549 citations)
  • Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division (1205 citations)
  • Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. (669 citations)

What are the main themes of his work throughout his whole career to date?

Tim Hunt spends much of his time researching Cell biology, Molecular biology, Biochemistry, Cell cycle and Protein biosynthesis. His work investigates the relationship between Cell biology and topics such as Cyclin that intersect with problems in Xenopus. His Molecular biology research is multidisciplinary, incorporating perspectives in Cyclin A1, Cyclin-dependent kinase 2, Mitogen-activated protein kinase kinase, Cyclin A and Cyclin D.

His Cyclin A study deals with Cyclin-dependent kinase complex intersecting with Cyclin-dependent kinase 3 and CDC2 Protein Kinase. His Cell cycle study combines topics in areas such as Kinase, Cell division and DNA replication. Tim Hunt combines subjects such as Reticulocyte, RNA, Messenger RNA, Translation and Ribosome with his study of Protein biosynthesis.

He most often published in these fields:

  • Cell biology (40.69%)
  • Molecular biology (30.88%)
  • Biochemistry (27.94%)

What were the highlights of his more recent work (between 2006-2018)?

  • Cell biology (40.69%)
  • Cell cycle (22.55%)
  • Cyclin-dependent kinase (13.24%)

In recent papers he was focusing on the following fields of study:

Tim Hunt focuses on Cell biology, Cell cycle, Cyclin-dependent kinase, Mitosis and Cyclin-dependent kinase 1. His Cell biology research integrates issues from Polo-like kinase and Cyclin B. His research integrates issues of Cyclin A and Cyclin D in his study of Cyclin B.

His research in Cell cycle intersects with topics in Circadian clock, Oscillating gene and Eukaryotic DNA replication. His Cyclin-dependent kinase study combines topics from a wide range of disciplines, such as Protein phosphatase 2 and Kinase. As part of his studies on Cyclin A2, Tim Hunt often connects relevant subjects like Molecular biology.

Between 2006 and 2018, his most popular works were:

  • Cyclin-dependent kinases and cell-cycle transitions: does one fit all? (341 citations)
  • Greatwall Phosphorylates an Inhibitor of Protein Phosphatase 2Α That Is Essential for Mitosis (316 citations)
  • Cyclin-dependent kinases: a family portrait (260 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Cell biology, Cell cycle, Mitosis, Cyclin-dependent kinase and Cyclin-dependent kinase 1 are his primary areas of study. His Cell biology research incorporates themes from Chromatin and Cyclin B. His studies in Cyclin B integrate themes in fields like Cyclin A2, Cyclin A, Fungal protein and Cyclin D.

The various areas that Tim Hunt examines in his Cell cycle study include Bacterial circadian rhythms, Circadian clock and Oscillating gene. The Cyclin-dependent kinase study which covers Protein phosphatase 2 that intersects with Interphase, Mitotic exit, Polo-like kinase, Maturation promoting factor and Protein kinase A. In his research on the topic of Kinase, Signal transduction is strongly related with Cyclin.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins.

John Rouse;Philip Cohen;Sylviane Trigon;Michel Morange.
Cell (1994)

2106 Citations

Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

Tom Evans;Eric T. Rosenthal;Jim Youngblom;Dan Distel.
Cell (1983)

2053 Citations

The Cell Cycle: An Introduction

Andrew Wood Murray;Tim Hunt.
(1993)

1005 Citations

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations.

P. J. Pollard;J. J. Briere;N. A. Alam;J. Barwell.
Human Molecular Genetics (2005)

945 Citations

Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis

Paul J. Farrell;Ken Balkow;Tim Hunt;Richard J. Jackson.
Cell (1977)

861 Citations

Cyclin is a component of maturation-promoting factor from Xenopus

Jean Gautier;Jeremy Minshull;Manfred Lohka;Michael Glotzer.
Cell (1990)

825 Citations

A brain-specific activator of cyclin-dependent kinase 5

John Lew;Qi Quan Huang;Zhong Qi;Robert J. Winkfein.
Nature (1994)

680 Citations

Preparation and use of nuclease-treated rabbit reticulocyte lysates for the translation of eukaryotic messenger RNA.

Richard J. Jackson;Tim Hunt.
Methods in Enzymology (1983)

624 Citations

Cyclin-dependent kinases and cell-cycle transitions: does one fit all?

Helfrid Hochegger;Shunichi Takeda;Tim Hunt.
Nature Reviews Molecular Cell Biology (2008)

599 Citations

Cut2 proteolysis required for sister-chromatid separation in fission yeast

Hironori Funabiki;Hiroyuki Yamano;Kazuki Kumada;Koji Nagao.
Nature (1996)

591 Citations

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