Tim Hunt

Research.com Recognitions

• 2005 - Fellow of the American Association for the Advancement of Science (AAAS)
• 2003 - Fellow of the Royal Society of Edinburgh
• 2001 - Nobel Prize for their discoveries of key regulators of the cell cycle
• 1999 - Member of the National Academy of Sciences
• 1998 - Member of Academia Europaea
• 1991 - Fellow of the Royal Society, United Kingdom

Overview

Best Publications

• A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins.

  John Rouse;Philip Cohen;Sylviane Trigon;Michel Morange

  2135
  Citations

• Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

  Tom Evans;Eric T. Rosenthal;Jim Youngblom;Dan Distel

  2121
  Citations

• The Cell Cycle: An Introduction

  Andrew Wood Murray;Tim Hunt

  1014
  Citations

• Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations.

  P. J. Pollard;J. J. Briere;N. A. Alam;J. Barwell

  997
  Citations

• Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis

  Paul J. Farrell;Ken Balkow;Tim Hunt;Richard J. Jackson

  869
  Citations

• Cyclin is a component of maturation-promoting factor from Xenopus

  Jean Gautier;Jeremy Minshull;Manfred Lohka;Michael Glotzer

  834
  Citations

• A brain-specific activator of cyclin-dependent kinase 5

  John Lew;Qi Quan Huang;Zhong Qi;Robert J. Winkfein

  692
  Citations

• Cyclin-dependent kinases and cell-cycle transitions: does one fit all?

  Helfrid Hochegger;Shunichi Takeda;Tim Hunt

  682
  Citations

• Preparation and use of nuclease-treated rabbit reticulocyte lysates for the translation of eukaryotic messenger RNA.

  Richard J. Jackson;Tim Hunt

  633
  Citations

• Cut2 proteolysis required for sister-chromatid separation in fission yeast

  Hironori Funabiki;Hiroyuki Yamano;Kazuki Kumada;Koji Nagao

  599
  Citations

• CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

  Fumiko Esashi;Nicole Christ;Julian Gannon;Yilun Liu

  569
  Citations

• Translation of Cyclin mRNA Is Necessary for Extracts of Activated Xenopus Eggs to Enter Mitosis

  Jeremy Minshull;J.Julian Blow;Tim Hunt

  548
  Citations

• The cdc2-related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2.

  R. Y. C. Poon;K. Yamashita;J. P. Adamczewski;T. Hunt

  530
  Citations

• Cyclin-dependent kinases: a family portrait

  Marcos Malumbres;Edward Harlow;Tim Hunt;Tony Hunter

  528
  Citations

• Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint.

  Stephan Geley;Edgar Kramer;Christian Gieffers;Julian Gannon

  512
  Citations

• The A‐ and B‐type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle.

  J. Minshull;R. Golsteyn;C. S. Hill;T. Hunt

  473
  Citations

• Greatwall Phosphorylates an Inhibitor of Protein Phosphatase 2Α That Is Essential for Mitosis

  Satoru Mochida;Sarah L. Maslen;Mark Skehel;Tim Hunt

  452
  Citations

• The 3'-untranslated regions of c-mos and cyclin mRNAs stimulate translation by regulating cytoplasmic polyadenylation.

  M D Sheets;C A Fox;T Hunt;G Vande Woude

  397
  Citations

• Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero

  Michael Brandeis;Ian Rosewell;Mark Carrington;Tessa Crompton

  397
  Citations

• The c-mos proto-oncogene protein kinase turns on and maintains the activity of MAP kinase, but not MPF, in cell-free extracts of Xenopus oocytes and eggs

  A R Nebreda;T Hunt

  389
  Citations