World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
23549
World Ranking
9986
National Ranking
763

Dominic J. Withers publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Dominic J. Withers sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 124 publications — 14th percentile

14% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Dominic J. Withers D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Dominic J. Withers sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 63 D-Index — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Dominic J. Withers is affiliated with Imperial College London in the United Kingdom. Their research spans multiple fields with a focus on medicine and biochemistry, genetics, and molecular biology. Their work engages significantly with subfields such as molecular biology, physiology, surgery, cellular and molecular neuroscience, and genetics.

Withers's research topics cover a variety of important areas, including:

  • Pancreatic function and diabetes
  • Adipose tissue and metabolism
  • Telomeres, telomerase, and senescence
  • Neurotransmitter receptor influence on behavior
  • Genetics, aging, and longevity in model organisms
  • Epigenetics and DNA methylation
  • Treatment of major depression

Their recent publications reflect a focus on cellular aging, senescence, and neurological disorders. Selected recent papers include:

  • "Inhibition of IL-11 signalling extends mammalian healthspan and lifespan," 2024, Nature
  • "Galactose-modified duocarmycin prodrugs as senolytics," 2020, Aging Cell
  • "Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamine," 2020, Molecular Psychiatry
  • "Detection of senescence using machine learning algorithms based on nuclear features," 2024, Nature Communications
  • "COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells," 2023, Nature Cell Biology

Their work has been published prominently in journals such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Endocrine Abstracts, Nature Cell Biology, and Diabetologia. They have contributed extensively to bioRxiv with eight publications in addition to multiple articles in these other venues.

Dominic J. Withers collaborates frequently with several researchers, including:

  • Jesús Gil
  • Elaine E. Irvine
  • Alex Montoya
  • Oliver Howes
  • Steven J. Millership

Across their career, Withers has contributed significantly to understanding molecular and cellular mechanisms underlying aging, metabolism, and neurological conditions, employing approaches from genetics to advanced imaging and machine learning.

Best Publications

  • Inhibition of food intake in obese subjects by peptide YY3-36.

    Rachel L Batterham;Mark A Cohen;Sandra M Ellis;Carel W Le Roux

  • Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

    Barbara T. Navé;D. Margriet Ouwens;Dominic J. Withers;Dario R. Alessi

  • Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

    Colin Selman;Jennifer M A Tullet;Daniela Wieser;Elaine Elizabeth Irvine

  • PHOSPHOINOSITIDE 3-KINASE : THE KEY SWITCH MECHANISM IN INSULIN SIGNALLING

    Peter R. Shepherd;Dominic J. Withers;Kenneth Siddle

  • Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands

    Susan J. Broughton;Matthew D. W. Piper;Tomoatsu Ikeya;Timothy M. Bass

  • Irs-2 coordinates Igf-1 receptor-mediated β-cell development and peripheral insulin signalling

    Dominic J. Withers;Deborah J. Burks;Heather H. Towery;Shari L. Altamuro

  • mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

    Nicolás Herranz;Suchira Gallage;Massimiliano Mellone;Torsten Wuestefeld

  • Critical role for peptide YY in protein-mediated satiation and body-weight regulation

    Rachel L. Batterham;Helen Heffron;Saloni Kapoor;Joanna E. Chivers

  • Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2

    Yoshiaki Kido;Deborah J. Burks;Dominic Withers;Jens C. Bruning

  • Sex and Death: What Is the Connection?

    Linda Partridge;David Gems;Dominic J. Withers

  • Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

    Colin Selman;Steven Lingard;Agharul I. Choudhury;Rachel L. Batterham

  • AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

    Marc Claret;Mark A. Smith;Rachel L. Batterham;Colin Selman

  • Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation

    Lazaros C. Foukas;Marc Claret;Wayne Pearce;Klaus Okkenhaug;Klaus Okkenhaug

  • PYY modulation of cortical and hypothalamic brain areas predicts feeding behaviour in humans

    Rachel L. Batterham;Dominic H. ffytche;J. Miranda Rosenthal;Fernando O. Zelaya

  • IRS-2 pathways integrate female reproduction and energy homeostasis

    Deborah J. Burks;Jaime Font de Mora;Markus Schubert;Dominic J. Withers

  • A link between FTO, ghrelin, and impaired brain food-cue responsivity

    Efthimia Karra;Owen G. O’Daly;Agharul I. Choudhury;Ahmed Yousseif

  • Contrasting Effects of IRS-1 Versus IRS-2 Gene Disruption on Carbohydrate and Lipid Metabolism in Vivo

    Stephen F. Previs;Dominic J. Withers;Jian-Ming Ren;Morris F. White

  • Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice.

    Rohit N. Kulkarni;Zhi Li Wang;Ren Ming Wang;James D. Hurley

  • Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

    Mohsen Malehmir;Dominik Pfister;Suchira Gallage;Marta Szydlowska

  • The role of insulin receptor substrate 2 in hypothalamic and β cell function

    Agharul I. Choudhury;Helen Heffron;Mark A. Smith;Hind Al-Qassab

Frequent Co-Authors

Colin Selman
Colin Selman University of Glasgow
Linda Partridge
Linda Partridge Max Planck Society
Morris F. White
Morris F. White Boston Children's Hospital
Oliver D. Howes
Oliver D. Howes King's College London
Mark A. Ungless
Mark A. Ungless Imperial College London
Michael L. J. Ashford
Michael L. J. Ashford University of Dundee
Jesús Gil
Jesús Gil Imperial College London
David Carling
David Carling Imperial College London
Enrique Rozengurt
Enrique Rozengurt University of California, Los Angeles
Stephen R. Bloom
Stephen R. Bloom Imperial College London

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