2023 - Research.com Neuroscience in Japan Leader Award
Neuroscience, Long-term potentiation, Synaptic plasticity, Hippocampal formation and Postsynaptic potential are his primary areas of study. His studies deal with areas such as Receptor, Neurotransmission and Muscarinic acetylcholine receptor M3 as well as Neuroscience. As part of his studies on Long-term potentiation, Toshiya Manabe frequently links adjacent subjects like Hippocampus.
His biological study spans a wide range of topics, including NMDA receptor, Tyrosine kinase, FYN and Protein tyrosine phosphatase. His Hippocampal formation study combines topics in areas such as Glutamate receptor, Protein subunit and LTP induction. His research in AMPA receptor focuses on subjects like Cell biology, which are connected to Kainate receptor and Long-term depression.
Toshiya Manabe focuses on Neuroscience, Long-term potentiation, Synaptic plasticity, Cell biology and Hippocampal formation. The study incorporates disciplines such as NMDA receptor, Postsynaptic potential and Neurotransmission in addition to Neuroscience. Toshiya Manabe has researched NMDA receptor in several fields, including Glutamate receptor and Phosphorylation.
His Long-term potentiation study incorporates themes from Ca2+/calmodulin-dependent protein kinase, Ionotropic effect and Excitatory postsynaptic potential. Synaptic plasticity is closely attributed to Long-term depression in his research. His study in Hippocampal formation is interdisciplinary in nature, drawing from both Synapse and Tetanic stimulation.
Toshiya Manabe mainly investigates Cell biology, Neuroscience, Receptor, Knockout mouse and AMPA receptor. Toshiya Manabe has included themes like Neurotransmission and Neural facilitation in his Cell biology study. His Neuroscience research is multidisciplinary, relying on both Tropomyosin receptor kinase B, Postsynaptic potential and Hereditary spastic paraplegia.
His research integrates issues of STIM1, Endocrinology and Intracellular in his study of Receptor. His AMPA receptor research incorporates elements of Synaptic plasticity, Postsynaptic density and Long-term potentiation. The Synaptic plasticity study combines topics in areas such as Glutamatergic, Stimulation and Cognition.
His main research concerns Neurotransmission, Neuroscience, Neural facilitation, Cell biology and Tropomyosin receptor kinase B. Toshiya Manabe has researched Neurotransmission in several fields, including GABARAP and GABAA receptor. When carried out as part of a general Neuroscience research project, his work on Synapse is frequently linked to work in Jacobsen syndrome, therefore connecting diverse disciplines of study.
His Neural facilitation study results in a more complete grasp of Synaptic plasticity. Many of his research projects under Cell biology are closely connected to Synaptic vesicle recycling and Synapsin with Synaptic vesicle recycling and Synapsin, tying the diverse disciplines of science together. Toshiya Manabe has included themes like Neurotrophin and Intracellular in his Tropomyosin receptor kinase B study.
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Epilepsy and Exacerbation of Brain Injury in Mice Lacking the Glutamate Transporter GLT-1
Kohichi Tanaka;Kei Watase;Toshiya Manabe;Keiko Yamada.
Science (1997)
Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor ε1 subunit
Kenji Sakimura;Tatsuya Kutsuwada;Isao Ito;Toshiya Manabe.
Nature (1995)
Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus
T. Manabe;D. J. A. Wyllie;D. J. Perkel;R. A. Nicoll.
Journal of Neurophysiology (1993)
Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor ε2 subunit mutant mice
Tatsuya Kutsuwada;Kenji Sakimura;Toshiya Manabe;Chitoshi Takayama.
Neuron (1996)
Characterization of Fyn-mediated tyrosine phosphorylation sites on GluRε2 (NR2B) subunit of the N-methyl-D-aspartate receptor
Takanobu Nakazawa;Shoji Komai;Tohru Tezuka;Chihiro Hisatsune.
Journal of Biological Chemistry (2001)
Postsynaptic contribution to long-term potentiation revealed by the analysis of miniature synaptic currents.
Toshiya Manabe;Pius Renner;Roger A. Nicoll.
Nature (1992)
Facilitation of long-term potentiation and memory in mice lacking nociceptin receptors
Toshiya Manabe;Yukihiro Noda;Takayoshi Mamiya;Hiroyuki Katagiri.
Nature (1998)
Impairment of hippocampal mossy fiber LTD in mice lacking mGluR2.
Mineto Yokoi;Katsunori Kobayashi;Toshiya Manabe;Tomoyuki Takahashi.
Science (1996)
Selective scarcity of NMDA receptor channel subunits in the stratum lucidum (mossy fibre‐recipient layer) of the mouse hippocampal CA3 subfield
Masahiko Watanabe;Masahiro Fukaya;Kenji Sakimura;Toshiya Manabe.
European Journal of Neuroscience (1998)
Two distinct classes of muscarinic action on hippocampal inhibitory synapses: M2-mediated direct suppression and M1/M3-mediated indirect suppression through endocannabinoid signalling.
Yuko Fukudome;Takako Ohno-Shosaku;Minoru Matsui;Yuko Omori.
European Journal of Neuroscience (2004)
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