H-Index & Metrics Top Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Neuroscience H-index 51 Citations 11,038 79 World Ranking 2243 National Ranking 51


What is he best known for?

The fields of study he is best known for:

  • Gene
  • Neurotransmitter
  • Neuron

Neuroscience, Long-term potentiation, Synaptic plasticity, Hippocampal formation and Postsynaptic potential are his primary areas of study. His studies deal with areas such as Receptor, Neurotransmission and Muscarinic acetylcholine receptor M3 as well as Neuroscience. As part of his studies on Long-term potentiation, Toshiya Manabe frequently links adjacent subjects like Hippocampus.

His biological study spans a wide range of topics, including NMDA receptor, Tyrosine kinase, FYN and Protein tyrosine phosphatase. His Hippocampal formation study combines topics in areas such as Glutamate receptor, Protein subunit and LTP induction. His research in AMPA receptor focuses on subjects like Cell biology, which are connected to Kainate receptor and Long-term depression.

His most cited work include:

  • Epilepsy and Exacerbation of Brain Injury in Mice Lacking the Glutamate Transporter GLT-1 (1468 citations)
  • Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor ε1 subunit (738 citations)
  • Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus (617 citations)

What are the main themes of his work throughout his whole career to date?

Toshiya Manabe focuses on Neuroscience, Long-term potentiation, Synaptic plasticity, Cell biology and Hippocampal formation. The study incorporates disciplines such as NMDA receptor, Postsynaptic potential and Neurotransmission in addition to Neuroscience. Toshiya Manabe has researched NMDA receptor in several fields, including Glutamate receptor and Phosphorylation.

His Long-term potentiation study incorporates themes from Ca2+/calmodulin-dependent protein kinase, Ionotropic effect and Excitatory postsynaptic potential. Synaptic plasticity is closely attributed to Long-term depression in his research. His study in Hippocampal formation is interdisciplinary in nature, drawing from both Synapse and Tetanic stimulation.

He most often published in these fields:

  • Neuroscience (69.57%)
  • Long-term potentiation (49.28%)
  • Synaptic plasticity (43.48%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cell biology (31.88%)
  • Neuroscience (69.57%)
  • Receptor (17.39%)

In recent papers he was focusing on the following fields of study:

Toshiya Manabe mainly investigates Cell biology, Neuroscience, Receptor, Knockout mouse and AMPA receptor. Toshiya Manabe has included themes like Neurotransmission and Neural facilitation in his Cell biology study. His Neuroscience research is multidisciplinary, relying on both Tropomyosin receptor kinase B, Postsynaptic potential and Hereditary spastic paraplegia.

His research integrates issues of STIM1, Endocrinology and Intracellular in his study of Receptor. His AMPA receptor research incorporates elements of Synaptic plasticity, Postsynaptic density and Long-term potentiation. The Synaptic plasticity study combines topics in areas such as Glutamatergic, Stimulation and Cognition.

Between 2013 and 2021, his most popular works were:

  • CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus and regulates seizure susceptibility (50 citations)
  • AMPA Receptor Activation-Independent Antidepressant Actions of Ketamine Metabolite (S)-Norketamine. (42 citations)
  • PX-RICS-deficient mice mimic autism spectrum disorder in Jacobsen syndrome through impaired GABAA receptor trafficking. (28 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Neurotransmitter
  • Neuron

His main research concerns Neurotransmission, Neuroscience, Neural facilitation, Cell biology and Tropomyosin receptor kinase B. Toshiya Manabe has researched Neurotransmission in several fields, including GABARAP and GABAA receptor. When carried out as part of a general Neuroscience research project, his work on Synapse is frequently linked to work in Jacobsen syndrome, therefore connecting diverse disciplines of study.

His Neural facilitation study results in a more complete grasp of Synaptic plasticity. Many of his research projects under Cell biology are closely connected to Synaptic vesicle recycling and Synapsin with Synaptic vesicle recycling and Synapsin, tying the diverse disciplines of science together. Toshiya Manabe has included themes like Neurotrophin and Intracellular in his Tropomyosin receptor kinase B study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Top Publications

Epilepsy and Exacerbation of Brain Injury in Mice Lacking the Glutamate Transporter GLT-1

Kohichi Tanaka;Kei Watase;Toshiya Manabe;Keiko Yamada.
Science (1997)

1813 Citations

Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor ε1 subunit

Kenji Sakimura;Tatsuya Kutsuwada;Isao Ito;Toshiya Manabe.
Nature (1995)

1160 Citations

Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampus

T. Manabe;D. J. A. Wyllie;D. J. Perkel;R. A. Nicoll.
Journal of Neurophysiology (1993)

692 Citations

Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor ε2 subunit mutant mice

Tatsuya Kutsuwada;Kenji Sakimura;Toshiya Manabe;Chitoshi Takayama.
Neuron (1996)

578 Citations

Characterization of Fyn-mediated tyrosine phosphorylation sites on GluRε2 (NR2B) subunit of the N-methyl-D-aspartate receptor

Takanobu Nakazawa;Shoji Komai;Tohru Tezuka;Chihiro Hisatsune.
Journal of Biological Chemistry (2001)

478 Citations

Postsynaptic contribution to long-term potentiation revealed by the analysis of miniature synaptic currents.

Toshiya Manabe;Pius Renner;Roger A. Nicoll.
Nature (1992)

473 Citations

Facilitation of long-term potentiation and memory in mice lacking nociceptin receptors

Toshiya Manabe;Yukihiro Noda;Takayoshi Mamiya;Hiroyuki Katagiri.
Nature (1998)

396 Citations

Selective scarcity of NMDA receptor channel subunits in the stratum lucidum (mossy fibre‐recipient layer) of the mouse hippocampal CA3 subfield

Masahiko Watanabe;Masahiro Fukaya;Kenji Sakimura;Toshiya Manabe.
European Journal of Neuroscience (1998)

392 Citations

Impairment of hippocampal mossy fiber LTD in mice lacking mGluR2.

Mineto Yokoi;Katsunori Kobayashi;Toshiya Manabe;Tomoyuki Takahashi.
Science (1996)

357 Citations

Two distinct classes of muscarinic action on hippocampal inhibitory synapses: M2-mediated direct suppression and M1/M3-mediated indirect suppression through endocannabinoid signalling.

Yuko Fukudome;Takako Ohno-Shosaku;Minoru Matsui;Yuko Omori.
European Journal of Neuroscience (2004)

336 Citations

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking h-index is inferred from publications deemed to belong to the considered discipline.

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