World's Best Scientists 2026 revealed!
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Biology and Biochemistry
Japan
2026
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Neuroscience
Japan
2026

D-Index & Metrics

Neuroscience

D-Index
105
Citations
43188
World Ranking
649
National Ranking
8

Biology and Biochemistry

D-Index
105
Citations
43359
World Ranking
1190
National Ranking
68

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2026 - Research.com Neuroscience in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Neuroscience in Japan Leader Award

Overview

Shigeyoshi Itohara is affiliated with the RIKEN Center for Brain Science in Japan and has a significant body of work primarily in the field of neuroscience. Their research spans several subfields including cellular and molecular neuroscience, cognitive neuroscience, molecular biology, neurology, and behavioral neuroscience.

The scientist's recent publications address diverse topics in neuroscience and related disciplines. Notable papers include:

  • CRISPR/dCas9-based Scn1a gene activation in inhibitory neurons ameliorates epileptic and behavioral phenotypes of Dravet syndrome model mice, 2020, Neurobiology of Disease
  • Calcitonin receptor signaling in the medial preoptic area enables risk-taking maternal care, 2021, Cell Reports
  • Transient Astrocytic Gq Signaling Underlies Remote Memory Enhancement, 2021, Frontiers in Neural Circuits
  • Amylin-Calcitonin receptor signaling in the medial preoptic area mediates affiliative social behaviors in female mice, 2022, Nature Communications
  • Netrin-G1 Regulates Microglial Accumulation along Axons and Supports the Survival of Layer V Neurons in the Postnatal Mouse Brain, 2020, Cell Reports

Shigeyoshi Itohara frequently collaborates with several researchers, including Mika Tanaka, Masahiko Watanabe, Kenji Sakimura, Tetsushi Yamagata, and Tetsuya Tatsukawa.

The scientist's work has been published repeatedly in a few key venues, indicating focus areas within the research community. The primary publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Molecular Brain
  • eLife
  • iScience

The main fields of study Shigeyoshi Itohara has contributed to are:

  • Neuroscience

More specialized subfields within this area reflect the specific aspects addressed in their research:

  • Cellular and Molecular Neuroscience
  • Cognitive Neuroscience
  • Molecular Biology
  • Neurology
  • Behavioral Neuroscience

The major themes of Shigeyoshi Itohara's research topics include:

  • Neuroscience and Neuropharmacology Research
  • Stress Responses and Cortisol
  • Neural dynamics and brain function
  • Axon Guidance and Neuronal Signaling
  • Neuroendocrine regulation and behavior
  • Memory and Neural Mechanisms
  • Nerve injury and regeneration

Best Publications

  • Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

    Gabriele Bergers;Rolf Brekken;Gerald McMahon;Thiennu H. Vu

  • Causal Relationship between the Loss of RUNX3 Expression and Gastric Cancer

    Qing Lin Li;Kosei Ito;Chohei Sakakura;Hiroshi Fukamachi

  • Single App knock-in mouse models of Alzheimer's disease

    Takashi Saito;Yukio Matsuba;Naomi Mihira;Jiro Takano

  • Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

    Peter Mombaerts;Alan R. Clarke;Michael A. Rudnicki;John Iacomini

  • Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain

    Itaru Imayoshi;Masayuki Sakamoto;Toshiyuki Ohtsuka;Keizo Takao;Keizo Takao

  • Reduced angiogenesis and tumor progression in gelatinase A-deficient mice.

    Takeshi Itoh;Masatoshi Tanioka;Hiroshi Yoshida;Takayuki Yoshioka

  • Nav1.1 Localizes to Axons of Parvalbumin-Positive Inhibitory Interneurons: A Circuit Basis for Epileptic Seizures in Mice Carrying an Scn1a Gene Mutation

    Ikuo Ogiwara;Hiroyuki Miyamoto;Noriyuki Morita;Nafiseh Atapour

  • The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis.

    Junseo Oh;Rei Takahashi;Shunya Kondo;Akira Mizoguchi

  • Innate versus learned odour processing in the mouse olfactory bulb

    Ko Kobayakawa;Reiko Kobayakawa;Hideyuki Matsumoto;Yuichiro Oka

  • Ventral CA1 neurons store social memory

    Teruhiro Okuyama;Takashi Kitamura;Dheeraj S. Roy;Shigeyoshi Itohara

  • Homing of a γδ thymocyte subset with homogeneous T-cell receptors to mucosal epithelia

    Shigeyoshi Itohara;Shigeyoshi Itohara;Shigeyoshi Itohara;Andrew G. Farr;Andrew G. Farr;Andrew G. Farr;Juan J. Lafaille;Juan J. Lafaille;Juan J. Lafaille;Marc Bonneville;Marc Bonneville;Marc Bonneville

  • T cell receptor δ gene mutant mice : independent generation of αβ T cells and programmed rearrangements of γδ TCR genes

    Shigeyoshi Itohara;Peter Mombaerts;Juan Lafaille;John Iacomini

  • Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex

    Takuji Iwasato;Akash Datwani;Alexander M. Wolf;Hiroshi Nishiyama

  • Prions prevent neuronal cell-line death.

    Chieko Kuwahara;Alice M. Takeuchi;Takuya Nishimura;Keiko Haraguchi

  • Cortical 5-HT2A Receptor Signaling Modulates Anxiety-Like Behaviors in Mice

    Noelia V. Weisstaub;Mingming Zhou;Alena Lira;Evelyn Lambe;Evelyn Lambe

  • Deficient Cerebellar Long-Term Depression, Impaired Eyeblink Conditioning, and Normal Motor Coordination in GFAP Mutant Mice

    Katsuei Shibuki;Hiroshi Gomi;Lu Chen;Shaowen Bao

  • Antagonistic negative and positive neurons of the basolateral amygdala

    Joshua Kim;Michele Pignatelli;Sangyu Xu;Shigeyoshi Itohara

  • Mutant mice and neuroscience: Recommendations concerning genetic background

    Alcino J. Silva;Elizabeth M. Simpson;Joseph S. Takahashi;Hans Peter Lipp

  • Homeostatic regulation of intestinal epithelia by intraepithelial gamma delta T cells

    H Komano;Y Fujiura;M Kawaguchi;S Matsumoto

  • The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface

    Silvia Cappello;Alessio Attardo;Xunwei Wu;Takuji Iwasato

  • Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice.

    Takeshi Itoh;Toshio Ikeda;Hiroshi Gomi;Shinobu Nakao

Frequent Co-Authors

Takashi Onodera
Takashi Onodera University of Tokyo
Kazuhiro Yamakawa
Kazuhiro Yamakawa Nagoya City University
Katsuhiko Mikoshiba
Katsuhiko Mikoshiba ShanghaiTech University
Toshiharu Suzuki
Toshiharu Suzuki Hokkaido University
Ryosuke Takahashi
Ryosuke Takahashi Kyoto University
Hajime Hirase
Hajime Hirase University of Copenhagen
Kenji Sakimura
Kenji Sakimura Niigata University
Takao K. Hensch
Takao K. Hensch Harvard University
Thomas J. McHugh
Thomas J. McHugh RIKEN Center for Brain Science

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