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David S. Bredt

D-Index & Metrics

Biology and Biochemistry

D-Index
124
Citations
87610
World Ranking
519
National Ranking
324

David S. Bredt publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where David S. Bredt sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 266 publications — 71st percentile

71% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

David S. Bredt D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where David S. Bredt sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 124 D-Index — 97th percentile

97% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 1995 - Fellow of Alfred P. Sloan Foundation

Overview

David S. Bredt is affiliated with Johnson & Johnson in the United States. Their research primarily falls within the domain of Biochemistry, Genetics, and Molecular Biology, with a total of 19 publications in this broad field. Within this area, Bredt's subfield expertise includes Molecular Biology, Computational Theory and Mathematics, Pharmacology, Radiology, Nuclear Medicine and Imaging, and Insect Science.

Their scientific work centers on several main topics, including:

  • Nicotinic Acetylcholine Receptors Study
  • Ion channel regulation and function
  • Receptor Mechanisms and Signaling
  • Computational Drug Discovery Methods
  • Microbial Natural Products and Biosynthesis
  • Phytochemical compounds biological activities
  • Monoclonal and Polyclonal Antibodies Research

Bredt's frequent publication venues include:

  • Nature Reviews Drug Discovery
  • Science
  • Phytomedicine
  • Nature Communications
  • Proceedings of the National Academy of Sciences

Recent papers authored or coauthored by David S. Bredt showcase a focus on drug discovery and receptor biology, including:

  • "Natural products in drug discovery: advances and opportunities" (2021, Nature Reviews Drug Discovery)
  • "Targeting receptor complexes: a new dimension in drug discovery" (2020, Nature Reviews Drug Discovery)
  • "Nicotinic acetylcholine receptor redux: Discovery of accessories opens therapeutic vistas" (2021, Science)
  • "The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis" (2022, Phytomedicine)
  • "Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology" (2020, Nature Communications)

Their frequent coauthors include José A. Matta, Shenyan Gu, Madhurima Dhara, Daniel Knowland, and İlkay Erdoğan Orhan.

David S. Bredt was awarded the title of Fellow of the Alfred P. Sloan Foundation in 1995.

Best Publications

  • Natural products in drug discovery: advances and opportunities.

    Atanas G Atanasov;Sergey B Zotchev;Verena M Dirsch

  • Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

    David S. Bredt;Solomon H. Snyder

  • Localization of nitric oxide synthase indicating a neural role for nitric oxide

    David S. Bredt;Paul M. Hwang;Solomon H. Snyder

  • Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase.

    David S. Bredt;Paul M. Hwang;Charles E. Glatt;Charles Lowenstein

  • Nitric oxide: a physiologic messenger molecule.

    D. S. Bredt;Solomon H Snyder

  • Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.

    Valina L. Dawson;Ted M. Dawson;Edythe D. London;David S. Bredt

  • Nitric oxide, a novel neuronal messenger.

    David S. Bredt;Solomon H. Snyder

  • Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues.

    Ted M. Dawson;David S. Bredt;Majid Fotuhi;Paul M. Hwang

  • Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum

    David S. Bredt;Solomon H. Snyder

  • Interaction of Nitric Oxide Synthase with the Postsynaptic Density Protein PSD-95 and α1-Syntrophin Mediated by PDZ Domains

    Jay E Brenman;Daniel S Chao;Stephen H Gee;Aaron W McGee

  • Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase

    David S. Bredt;Charles E. Glatt;Paul M. Hwang;Majid Fotuhi

  • Targeted disruption of the neuronal nitric oxide synthase gene

    Paul L. Huang;Ted M. Dawson;David S. Bredt;Solomon H. Snyder

  • Nitric oxide: a physiologic mediator of penile erection

    Arthur L. Burnett;Charles J. Lowenstein;David S. Bredt;Thomas S. K. Chang

  • AMPA Receptor Trafficking at Excitatory Synapses

    David S Bredt;Roger A Nicoll

  • Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms

    Lu Chen;Dane M. Chetkovich;Ronald S. Petralia;Neal T. Sweeney

  • Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy.

    Jay E. Brenman;Daniel S. Chao;Houhui Xia;Kenneth D Aldape

  • Nitric oxide in skeletal muscle

    Lester Kobzik;Michael B. Reid;David S. Bredt;Jonathan S. Stamler

  • Biological Roles of Nitric Oxide

    Solomon H. Snyder;David S. Bredt

  • Endogenous nitric oxide synthesis: Biological functions and pathophysiology

    David S. Bredt

  • Generation of superoxide by purified brain nitric oxide synthase.

    S Pou;W S Pou;D S Bredt;S H Snyder

Frequent Co-Authors

Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine
Roger A. Nicoll
Roger A. Nicoll University of California, San Francisco
Ted M. Dawson
Ted M. Dawson Johns Hopkins University School of Medicine
Paul M. Hwang
Paul M. Hwang National Institutes of Health
Masaki Fukata
Masaki Fukata The Graduate University for Advanced Studies, SOKENDAI
Yuko Fukata
Yuko Fukata National Institutes of Natural Sciences
Yuan Xiang Tao
Yuan Xiang Tao Rutgers, The State University of New Jersey
Chiye Aoki
Chiye Aoki New York University
Ronald S. Petralia
Ronald S. Petralia National Institutes of Health
Charles J. Lowenstein
Charles J. Lowenstein Johns Hopkins University School of Medicine

External Links

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Best Scientists Citing David S. Bredt

Solomon H. Snyder

Solomon H. Snyder

Johns Hopkins University School of Medicine

Publications: 148

Morgan Sheng

Morgan Sheng

Broad Institute

Publications: 129

Stuart A. Lipton

Stuart A. Lipton

Scripps Research Institute

Publications: 123

Bernd Mayer

Bernd Mayer

University of Graz

Publications: 121

Ted M. Dawson

Ted M. Dawson

Johns Hopkins University School of Medicine

Publications: 98

Paul L. Huang

Paul L. Huang

Harvard University

Publications: 93

Richard L. Huganir

Richard L. Huganir

Johns Hopkins University School of Medicine

Publications: 93

Valina L. Dawson

Valina L. Dawson

Johns Hopkins University School of Medicine

Publications: 87

Daniel Choquet

Daniel Choquet

University of Bordeaux

Publications: 83

Dennis J. Stuehr

Dennis J. Stuehr

Cleveland Clinic Lerner College of Medicine

Publications: 78

Arthur L. Burnett

Arthur L. Burnett

Johns Hopkins University School of Medicine

Publications: 76

Roger A. Nicoll

Roger A. Nicoll

University of California, San Francisco

Publications: 75

Masaki Fukata

Masaki Fukata

The Graduate University for Advanced Studies, SOKENDAI

Publications: 69

Eunjoon Kim

Eunjoon Kim

Korea Advanced Institute of Science and Technology

Publications: 69

Geoffrey Burnstock

Geoffrey Burnstock

University College London

Publications: 66

Seth G. N. Grant

Seth G. N. Grant

University of Edinburgh

Publications: 65

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