World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
38280
World Ranking
4202
National Ranking
2056

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Charles J. Lowenstein is affiliated with Johns Hopkins University School of Medicine in the United States. Their research primarily focuses on Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to several subfields including Hematology, Molecular Biology, Infectious Diseases, Cancer Research, and Genetics.

Their work addresses topics such as COVID-19 Clinical Research Studies, Blood Coagulation and Thrombosis Mechanisms, Long-Term Effects of COVID-19, Hemophilia Treatment and Research, Platelet Disorders and Treatments, Myeloproliferative Neoplasms: Diagnosis and Treatment, and Acute Myeloid Leukemia Research.

Notable recent papers include:

  • "Severe COVID-19 Is a Microvascular Disease," 2020, Circulation
  • "Inflammation and cardiovascular disease: From mechanisms to therapeutics," 2020, American Journal of Preventive Cardiology
  • "Myocardial Injury in Severe COVID-19 Compared With Non-COVID-19 Acute Respiratory Distress Syndrome," 2020, Circulation
  • "Dyslipidemia," 2023, Annals of Internal Medicine
  • "The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function," 2020, Nature Communications

Frequent co-authors in their collaborations include:

  • Marios Arvanitis
  • Paula Reventún
  • William O. Osburn
  • Maria Viskadourou
  • Nunzio Alcharani

Their publications are often found in venues such as:

  • Circulation
  • UNC Libraries
  • Nature Communications
  • Blood
  • PLoS ONE

Charles J. Lowenstein holds the distinction of being a member of the Association of American Physicians. Their research contributions encompass a comprehensive approach to understanding and addressing complex medical conditions, particularly those related to cardiovascular disease and hematologic disorders.

Best Publications

  • Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase.

    David S. Bredt;Paul M. Hwang;Charles E. Glatt;Charles Lowenstein

  • Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

    Tsung Cheng Chang;Erik A. Wentzel;Oliver A. Kent;Kalyani Ramachandran

  • Tumor necrosis factor-α is required in the protective immune response against mycobacterium tuberculosis in mice

    Jo Anne L. Flynn;Marsha M. Goldstein;John Chan;Karla J. Triebold

  • The Central Role of CD4+ T Cells in the Antitumor Immune Response

    Kenneth Hung;Robert Hayashi;Anne Lafond-Walker;Charles Lowenstein

  • miR-34a repression of SIRT1 regulates apoptosis

    Munekazu Yamakuchi;Marcella Ferlito;Charles J. Lowenstein

  • Nitric oxide: a physiologic mediator of penile erection

    Arthur L. Burnett;Charles J. Lowenstein;David S. Bredt;Thomas S. K. Chang

  • Nitric oxide: A physiologic messenger

    Charles J. Lowenstein;Jay L. Dinerman;Solomon H. Snyder

  • Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide

    Charles J. Lowenstein;Evan W. Alley;Prafulla Raval;Adele M. Snowman

  • MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1

    Tamia A. Harris;Munekazu Yamakuchi;Marcella Ferlito;Joshua T. Mendell

  • Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes.

    D A Geller;C J Lowenstein;R A Shapiro;A K Nussler

  • Nitric oxide, a novel biologic messenger

    Charles J. Lowenstein;Solomon H. Snyder

  • Nitric oxide synthase in human and rat lung: immunocytochemical and histochemical localization.

    L. Kobzik;D. S. Bredt;C. J. Lowenstein;J. Drazen

  • Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide.

    R B Lorsbach;W J Murphy;C J Lowenstein;S H Snyder

  • Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes.

    D A Geller;A K Nussler;M Di Silvio;C J Lowenstein

  • Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.

    Charles J. Lowenstein;Charles S. Glatt;David S. Bredt;Solomon H. Snyder

  • MiR-34, SIRT1 and p53 : The feedback loop

    Munekazu Yamakuchi;Charles J. Lowenstein

  • Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro.

    Jean-Luc Balligand;D Ungureanu-Longrois;W W Simmons;D Pimental

  • P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

    Munekazu Yamakuchi;Craig D. Lotterman;Clare Bao;Ralph H. Hruban

  • Nitric Oxide Regulates Exocytosis by S-Nitrosylation of N-ethylmaleimide-Sensitive Factor

    Kenji Matsushita;Craig N Morrell;Beatrice Cambien;Shui Xiang Yang

  • Molecular mechanisms of nitric oxide regulation. Potential relevance to cardiovascular disease.

    J L Dinerman;C J Lowenstein;S H Snyder

Frequent Co-Authors

Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine
Thomas Michel
Thomas Michel Brigham and Women's Hospital
William M. Baldwin
William M. Baldwin Cleveland Clinic Lerner College of Medicine
Toren Finkel
Toren Finkel University of Pittsburgh
Eduardo Marbán
Eduardo Marbán Cedars-Sinai Medical Center
Roberto Bolli
Roberto Bolli University of Louisville
Nicholas L. Smith
Nicholas L. Smith University of Washington
Rudi Busse
Rudi Busse Goethe University Frankfurt
David S. Bredt
David S. Bredt Johnson & Johnson (United States)
David A. Kass
David A. Kass Johns Hopkins University School of Medicine

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Charles J. Lowenstein

Trending Scientists

Recently Published Articles