Colin Kleanthous

Research.com Recognitions

• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)

Overview

Best Publications

• Im7 folding mechanism: misfolding on a path to the native state.

  Andrew P. Capaldi;Colin Kleanthous;Sheena E. Radford

  314
  Citations

• RsrA, an anti-sigma factor regulated by redox change.

  Ju‐Gyeong Kang;Mark S.B. Paget;Mark S.B. Paget;Yeong‐Jae Seok;Mi‐Young Hahn

  304
  Citations

• Rapid folding with and without populated intermediates in the homologous four-helix proteins Im7 and Im9.

  Neil Ferguson;Andrew P Capaldi;Richard James;Colin Kleanthous

  281
  Citations

• The biology of E colicins: paradigms and paradoxes

  Richard James;Colin Kleanthous;Geoffrey R. Moore

  270
  Citations

• High-resolution mass spectrometry of small molecules bound to membrane proteins.

  Joseph Gault;Joseph A C Donlan;Idlir Liko;Jonathan T S Hopper

  250
  Citations

• Structural and Functional Analysis of SGT1 Reveals That Its Interaction with HSP90 Is Required for the Accumulation of Rx, an R Protein Involved in Plant Immunity

  Marta Botër;Béatrice Amigues;Jack Peart;Christian Breuer

  237
  Citations

• Structural and mechanistic basis of immunity toward endonuclease colicins

  Colin Kleanthous;Ulrike C. Kühlmann;Ansgar J. Pommer;Neil Ferguson

  225
  Citations

• Supramolecular assemblies underpin turnover of outer membrane proteins in bacteria

  Patrice Rassam;Nikki A Copeland;Oliver Birkholz;Csaba Tóth

  211
  Citations

• Protein-Protein Interactions in Colicin E9 DNase-Immunity Protein Complexes. 1. Diffusion-Controlled Association and Femtomolar Binding for the Cognate Complex

  Russell Wallis;Geoffrey R. Moore;Richard James;Colin Kleanthous

  195
  Citations

• Ultrarapid mixing experiments reveal that Im7 folds via an on-pathway intermediate

  Andrew P. Capaldi;M. C. Ramachandra Shastry;Colin Kleanthous;Heinrich Roder

  184
  Citations

• Specificity in protein-protein interactions: the structural basis for dual recognition in endonuclease colicin-immunity protein complexes.

  Ulrike C Kühlmann;Ansgar J Pommer;Geoffrey R Moore;Richard James

  181
  Citations

• Swimming against the tide: progress and challenges in our understanding of colicin translocation.

  Colin Kleanthous

  181
  Citations

• Mutational analysis of RsrA, a zinc-binding anti-sigma factor with a thiol–disulphide redox switch

  Mark S.B. Paget;Jae Bum Bae;Mi Young Hahn;Wei Li

  160
  Citations

• Mechanism and cleavage specificity of the H-N-H endonuclease colicin E9.

  Ansgar J Pommer;Santiago Cal;Anthony H Keeble;Daniel Walker

  153
  Citations

• Structural parsimony in endonuclease active sites: should the number of homing endonuclease families be redefined?

  Ulrike C. Kühlmann;Geoffrey R. Moore;Richard James;Colin Kleanthous

  143
  Citations

• Immunity proteins: enzyme inhibitors that avoid the active site.

  Colin Kleanthous;Daniel Walker

  135
  Citations

• The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction.

  Nicola A. G. Meenan;Amit Sharma;Sarel J. Fleishman;Colin J. MacDonald

  134
  Citations

• The Role of zinc in the disulphide stress-regulated anti-sigma factor RsrA from Streptomyces coelicolor.

  Wei Li;Andrew R. Bottrill;Maureen J. Bibb;Mark J. Buttner

  133
  Citations

• Intrinsically Disordered Protein Threads Through the Bacterial Outer-Membrane Porin OmpF

  Nicholas G. Housden;Jonathan T. S. Hopper;Natalya Lukoyanova;David Rodriguez-Larrea

  132
  Citations

• Cell entry mechanism of enzymatic bacterial colicins: porin recruitment and the thermodynamics of receptor binding.

  Nicholas G. Housden;Steven R. Loftus;Geoffrey R. Moore;Richard James

  124
  Citations