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47
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18773
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1464

Overview

Russell Wallis is affiliated with the University of Leicester in the United Kingdom. Their research primarily focuses on medical and immunological topics, with particular attention to infectious diseases and the complement system in diseases. They have contributed to fields including Medicine, Immunology and Microbiology, Infectious Diseases, Neurology, and Epidemiology.

The main topics addressed in Wallis's research include the complement system in diseases, SARS-CoV-2 and COVID-19 research, traumatic brain injury and neurovascular disturbances, antifungal resistance and susceptibility, bacterial infections and vaccines, COVID-19 clinical research studies, and mechanisms related to neuroinflammation and neurodegeneration.

Wallis has published several recent papers covering a range of topics:

  • Rationale for targeting complement in COVID-19, 2020, EMBO Molecular Medicine
  • Targeted deletions of complement lectin pathway genes improve outcome in traumatic brain injury, with MASP-2 playing a major role, 2020, Acta Neuropathologica Communications
  • Inactivation of the Complement Lectin Pathway by Candida tropicalis Secreted Aspartyl Protease-1, 2022, Immunobiology
  • Crystal structure of an inulosucrase from Halalkalicoccus jeotgali B3T, a halophilic archaeal strain, 2021, FEBS Journal
  • Formation of pre-pore complexes of pneumolysin is accompanied by a decrease in short-range order of lipid molecules throughout vesicle bilayers, 2020, Scientific Reports

Their research is frequently published in several venues, demonstrating a range in focus and interdisciplinary collaboration. These publication venues include:

  • Immunobiology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • EMBO Molecular Medicine
  • Acta Neuropathologica Communications
  • FEBS Journal

Wallis frequently collaborates with several researchers who have contributed multiple times alongside them. Frequent co-authors include:

  • Anastasia Polycarpou
  • Roseanna Greenlaw
  • Linda S. Klavinskis
  • Steven H. Sacks
  • Hasan Yeşilkaya

Best Publications

  • Site-Directed Conjugation of “Clicked” Glycopolymers To Form Glycoprotein Mimics: Binding to Mammalian Lectin and Induction of Immunological Function

    Jin Geng;Giuseppe Mantovani;Lei Tao;Julien Nicolas

  • Simultaneous Activation of Complement and Coagulation by MBL-Associated Serine Protease 2

    Anders Krarup;Russell Wallis;Russell Wallis;Julia S. Presanis;Péter Gál

  • Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury

    Wilhelm J. Schwaeble;Nicholas J. Lynch;James E. Clark;Michael Marber

  • Sequence‐Controlled Multi‐Block Glycopolymers to Inhibit DC‐SIGN‐gp120 Binding

    Qiang Zhang;Jennifer Collins;Athina Anastasaki;Russell Wallis

  • Paths reunited: Initiation of the classical and lectin pathways of complement activation.

    Russell Wallis;Daniel Anthony Mitchell;Ralf Schmid;Wilhelm J. Schwaeble

  • High-Affinity Glycopolymer Binding to Human DC-SIGN and Disruption of DC-SIGN Interactions with HIV Envelope Glycoprotein

    C. Remzi Becer;Matthew I. Gibson;Jin Geng;Rebecca Ilyas

  • The Hemopexin and O-Glycosylated Domains Tune Gelatinase B/MMP-9 Bioavailability via Inhibition and Binding to Cargo Receptors

    Philippe E. Van den Steen;Ilse Van Aelst;Vibeke Hvidberg;Helene Piccard

  • The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection

    Youssif M. Ali;Nicholas J. Lynch;Kashif S. Haleem;Teizo Fujita

  • Protein-Protein Interactions in Colicin E9 DNase-Immunity Protein Complexes. 1. Diffusion-Controlled Association and Femtomolar Binding for the Cognate Complex

    Russell Wallis;Geoffrey R. Moore;Richard James;Colin Kleanthous

  • Two Mechanisms for Mannose-binding Protein Modulation of the Activity of Its Associated Serine Proteases

    Ce-Belle Chen;Russell Wallis

  • Interactions between mannose-binding lectin and MASPs during complement activation by the lectin pathway.

    Russell Wallis

  • Dendritic Cell Lectin-Targeting Sentinel-like Unimolecular Glycoconjugates To Release an Anti-HIV Drug

    Qiang Zhang;Lu Su;Jennifer Collins;Guosong Chen

  • Stoichiometry of complexes between mannose-binding protein and its associated serine proteases. Defining functional units for complement activation.

    Ce-Belle Chen;Russell Wallis

  • Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2

    Hadar Feinberg;Joost C.M. Uitdehaag;Jason M. Davies;Russell Wallis

  • Molecular Determinants of Oligomer Formation and Complement Fixation in Mannose-binding Proteins *

    Russell Wallis;Kurt Drickamer

  • Interaction of mannose-binding protein with associated serine proteases: effects of naturally occurring mutations.

    Russell Wallis;Roger B. Dodd

  • Rationale for targeting Complement in COVID-19.

    Anastasia Polycarpou;Mark Howard;Conrad A Farrar;Roseanna Greenlaw

  • Characterization and membrane assembly of the TatA component of the Escherichia coli twin-arginine protein transport system.

    Ida Porcelli;Erik de Leeuw;Russell Wallis;Els van den Brink-van der Laan

  • Conformational changes in the AAA ATPase p97-p47 adaptor complex

    Fabienne Beuron;Ingrid Dreveny;Xuemei Yuan;Valerie E. Pye

  • Protein-protein interactions in colicin E9 DNase-immunity protein complexes. 2. Cognate and noncognate interactions that span the millimolar to femtomolar affinity range

    Russell Wallis;Kit-Yi Leung;Ansgar J. Pommer;Hortense Videler

Frequent Co-Authors

Wilhelm J. Schwaeble
Wilhelm J. Schwaeble University of Leicester
Colin Kleanthous
Colin Kleanthous University of Oxford
Geoffrey R. Moore
Geoffrey R. Moore University of East Anglia
C. Remzi Becer
C. Remzi Becer University of Warwick
Robert B. Sim
Robert B. Sim University of Oxford
David M. Haddleton
David M. Haddleton University of Warwick
Kenneth B. M. Reid
Kenneth B. M. Reid University of Oxford
Qiang Zhang
Qiang Zhang Dalian University of Technology
Peter W. Andrew
Peter W. Andrew University of Leicester
Kurt Drickamer
Kurt Drickamer Imperial College London

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