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Biology and Biochemistry

D-Index
64
Citations
11556
World Ranking
9886
National Ranking
752

Overview

Wilhelm J. Schwaeble is affiliated with the University of Leicester in the United Kingdom. Their research primarily focuses on the field of Medicine, with specific contributions in Infectious Diseases, Neurology, Immunology, Nephrology, and Obstetrics and Gynecology.

The scientist's work covers several main topics, including:

  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Complement system in diseases
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Renal Diseases and Glomerulopathies
  • SARS-CoV-2 detection and testing
  • Long-Term Effects of COVID-19

Among the recent papers featuring Wilhelm J. Schwaeble's research contributions are:

  • Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins, 2021, Frontiers in Immunology
  • The Contribution of Complement to the Pathogenesis of IgA Nephropathy: Are Complement-Targeted Therapies Moving from Rare Disorders to More Common Diseases?, 2021, Journal of Clinical Medicine
  • Analysis of Serological Biomarkers of SARS-CoV-2 Infection in Convalescent Samples From Severe, Moderate and Mild COVID-19 Cases, 2021, Frontiers in Immunology
  • Role of the lectin pathway of complement in hematopoietic stem cell transplantation-associated endothelial injury and thrombotic microangiopathy, 2021, Experimental Hematology and Oncology
  • Targeted deletions of complement lectin pathway genes improve outcome in traumatic brain injury, with MASP-2 playing a major role, 2020, Acta Neuropathologica Communications

Frequent co-authors collaborating with Wilhelm J. Schwaeble include:

  • Nicholas J. Lynch
  • Jonathan L. Heeney
  • Gregory Demopulos
  • Youssif M. Ali
  • Thomas Dudler

The scientist has published predominantly in the following venues:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Medicine
  • Experimental Hematology and Oncology
  • Acta Neuropathologica Communications

Best Publications

  • Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.

    Rachael A Evans;Hamish McAuley;Ewen M Harrison;Aarti Shikotra

  • Biochemical and functional characterization of the interaction between pentraxin 3 and C1q.

    Alma J. Nauta;Barbara Bottazzi;Alberto Mantovani;Alberto Mantovani;Giovanni Salvatori

  • Direct binding of C1q to apoptotic cells and cell blebs induces complement activation.

    Alma J. Nauta;Leendert A. Trouw;Mohamed R. Daha;Odette Tijsma

  • L-Ficolin Specifically Binds to Lipoteichoic Acid, a Cell Wall Constituent of Gram-Positive Bacteria, and Activates the Lectin Pathway of Complement

    Nicholas J. Lynch;Silke Roscher;Thomas Hartung;Siegfried Morath

  • Natural Substrates and Inhibitors of Mannan-Binding Lectin-Associated Serine Protease-1 and -2: A Study on Recombinant Catalytic Fragments

    Géza Ambrus;Péter Gál;Mayumi Kojima;Katalin Szilágyi

  • Distinct pathways of mannan-binding lectin (MBL)- and C1-complex autoactivation revealed by reconstitution of MBL with recombinant MBL-associated serine protease-2.

    Thomas Vorup-Jensen;Steen V. Petersen;Annette G. Hansen;Knud Poulsen

  • Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury

    Wilhelm J. Schwaeble;Nicholas J. Lynch;James E. Clark;Michael Marber

  • Paths reunited: Initiation of the classical and lectin pathways of complement activation.

    Russell Wallis;Daniel Anthony Mitchell;Ralf Schmid;Wilhelm J. Schwaeble

  • The mannan-binding lectin-associated serine proteases (MASPs) and MAp19: four components of the lectin pathway activation complex encoded by two genes.

    Wilhelm Schwaeble;Mads R. Dahl;Steffen Thiel;Cordula Stover

  • The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection

    Youssif M. Ali;Nicholas J. Lynch;Kashif S. Haleem;Teizo Fujita

  • Complement C1q Is Dramatically Up-Regulated in Brain Microglia in Response to Transient Global Cerebral Ischemia

    Martin K.-H. Schäfer;Wilhelm J. Schwaeble;Wilhelm J. Schwaeble;Claes Post;Patricia Salvati

  • Interaction of C1q and Mannan-Binding Lectin (MBL) with C1r, C1s, MBL-Associated Serine Proteases 1 and 2, and the MBL-Associated Protein MAp19

    Steffen Thiel;Steen V. Petersen;Thomas Vorup-Jensen;Misao Matsushita

  • The Classical Activation Pathway of the Human Complement System Is Specifically Inhibited by Calreticulin from Trypanosoma cruzi

    Viviana Ferreira;Carolina Valck;Gittith Sánchez;Alexandre Gingras

  • The complement system in ischemia–reperfusion injuries

    William B. Gorsuch;Elvina Chrysanthou;Wilhelm J. Schwaeble;Gregory L. Stahl

  • Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury

    Conrad A. Farrar;David Tran;Ke Li;Weiju Wu

  • Activation of mannan-binding lectin-associated serine proteases leads to generation of a fibrin clot.

    Krishana C. Gulla;Kshitij Gupta;Anders Krarup;Peter Gal

  • Ficolins: novel pattern recognition molecules of the innate immune response.

    Valeria L. Runza;Wilhelm Schwaeble;Daniela N. Männel

  • Does properdin crosslink the cellular and the humoral immune response

    Wilhelm J Schwaeble;Kenneth B.M Reid

  • Human complement factor H: expression of an additional truncated gene product of 43 kDa in human liver.

    Wilhelm Schwaeble;Jörg Zwirner;Thomas F. Schulz;Reinhold P. Linke

  • Expression of C1q, a subcomponent of the rat complement system, is dramatically enhanced in brains of rats with either Borna disease or experimental allergic encephalomyelitis

    Bernhard Dietzschold;Wilhelm Schwaeble;Martin K.H. Schäfer;Martin K.H. Schäfer;D.Craig Hooper

Frequent Co-Authors

Robert B. Sim
Robert B. Sim University of Oxford
Russell Wallis
Russell Wallis University of Leicester
Teizo Fujita
Teizo Fujita Fukushima Prefectural General Hygiene Institute
Steffen Thiel
Steffen Thiel Aarhus University
Kenneth B. M. Reid
Kenneth B. M. Reid University of Oxford
Manfred P. Dierich
Manfred P. Dierich Innsbruck Medical University
Jens C. Jensenius
Jens C. Jensenius Aarhus University
Misao Matsushita
Misao Matsushita Tokai University
Eberhard Weihe
Eberhard Weihe Philipp University of Marburg
Peter W. Andrew
Peter W. Andrew University of Leicester

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