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Biology and Biochemistry

D-Index
54
Citations
38582
World Ranking
15325
National Ranking
6392

Overview

Manuel Garber is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research spans several interdisciplinary fields, primarily focusing on biochemistry, genetics, molecular biology, medicine, immunology, and microbiology. The scientist also specializes in subfields such as molecular biology, immunology, cell biology, infectious diseases, and epidemiology.

Garber's work covers a range of topics including melanin and skin pigmentation, T-cell and B-cell immunology, RNA modifications and cancer, epigenetics and DNA methylation, immune cell function and interaction, atherosclerosis and cardiovascular diseases, and genomics and chromatin dynamics.

Recent papers authored or coauthored by Manuel Garber include:

  • SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues (2020), published in Cell
  • scRNA-seq of human vitiligo reveals complex networks of subclinical immune activation and a role for CCR5 in T reg function (2021), published in Science Translational Medicine
  • An atlas of cell types in the mouse epididymis and vas deferens (2020), published in eLife
  • Simultaneous profiling of multiple chromatin proteins in the same cells (2021), published in Molecular Cell
  • HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells (2020), published in Nature Immunology

The scientist frequently publishes in several venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Investigative Dermatology
  • ENCODE Datasets
  • Molecular Cell
  • Cell

Manuel Garber collaborates regularly with a group of coauthors, notably:

  • Kyle Gellatly
  • John E. Harris
  • Patrick McDonel
  • Elisa Donnard
  • Khashayar Afshari

Best Publications

  • Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

    Mitchell Guttman;Ido Amit;Manuel Garber;Courtney French

  • Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

    Ahmad M. Khalil;Mitchell Guttman;Maite Huarte;Manuel Garber

  • Genome sequence, comparative analysis and haplotype structure of the domestic dog

    Kerstin Lindblad-Toh;Claire M Wade;Claire M Wade;Tarjei S. Mikkelsen;Tarjei S. Mikkelsen;Elinor K. Karlsson;Elinor K. Karlsson

  • SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.

    Carly G.K. Ziegler;Samuel J. Allon;Sarah K. Nyquist;Ian M. Mbano

  • A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

    Maite Huarte;Mitchell Guttman;Mitchell Guttman;David Feldser;Manuel Garber

  • lincRNAs act in the circuitry controlling pluripotency and differentiation

    Mitchell Guttman;Julie Donaghey;Bryce W. Carey;Manuel Garber

  • Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs

    Mitchell Guttman;Manuel Garber;Joshua Z Levin;Julie Donaghey

  • A high-resolution map of human evolutionary constraint using 29 mammals.

    Kerstin Lindblad-Toh;Manuel Garber;Or Zuk;Michael F. Lin;Michael F. Lin

  • Computational methods for transcriptome annotation and quantification using RNA-seq

    Manuel Garber;Manfred G Grabherr;Mitchell Guttman;Cole Trapnell;Cole Trapnell

  • Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals

    Upasna Sharma;Colin C. Conine;Jeremy M. Shea;Ana Boskovic

  • Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

    Sabine Loewer;Moran N Cabili;Moran N Cabili;Mitchell Guttman;Yuin-Han Loh

  • Genome sequence, comparative analysis, and population genetics of the domestic horse.

    C. M. Wade;E. Giulotto;S. Sigurdsson;M. Zoli

  • Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis

    Andrea Pauli;Eivind Valen;Michael F. Lin;Manuel Garber

  • Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

    Tarjei S. Mikkelsen;Tarjei S. Mikkelsen;Matthew J. Wakefield;Bronwen Aken;Chris T. Amemiya

  • Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus

    Sofia A. Quinodoz;Noah Ollikainen;Barbara Tabak;Ali Palla

  • Functional annotation of native enhancers with a Cas9–histone demethylase fusion

    Nicola A. Kearns;Hannah Pham;Barbara Tabak;Ryan M. J. Genga

  • Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells

    Michal Rabani;Joshua Z Levin;Lin Fan;Xian Adiconis

  • A Composite of Multiple Signals Distinguishes Causal Variants in Regions of Positive Selection

    Sharon R. Grossman;Sharon R. Grossman;Ilya Shylakhter;Ilya Shylakhter;Elinor K. Karlsson;Elinor K. Karlsson;Elizabeth H. Byrne;Elizabeth H. Byrne

  • Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses.

    Ido Amit;Manuel Garber;Nicolas Chevrier;Ana Paula Leite;Ana Paula Leite

  • A high throughput Chromatin ImmunoPrecipitation approach reveals principles of dynamic gene regulation in mammals

    Manuel Garber;Nir Yosef;Nir Yosef;Alon Goren;Raktima Raychowdhury

Frequent Co-Authors

Aviv Regev
Aviv Regev Genentech
Eric S. Lander
Eric S. Lander Broad Institute
Mitchell Guttman
Mitchell Guttman California Institute of Technology
John L. Rinn
John L. Rinn University of Colorado Boulder
Ido Amit
Ido Amit Weizmann Institute of Science
Nir Hacohen
Nir Hacohen Harvard University
Bradley E. Bernstein
Bradley E. Bernstein Broad Institute
Michael C. Zody
Michael C. Zody New York Genome Center
Andreas Gnirke
Andreas Gnirke Broad Institute
Oliver J. Rando
Oliver J. Rando University of Massachusetts Chan Medical School

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