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Frank E. McDonald

Frank E. McDonald

D-Index & Metrics

Chemistry

D-Index
50
Citations
6353
World Ranking
14613
National Ranking
3732

Research.com Recognitions

  • 1995 - Fellow of Alfred P. Sloan Foundation

Overview

Frank E. McDonald is affiliated with Emory University in the United States. Their research spans multiple areas primarily within chemistry and medicine, focusing notably on organic chemistry and ophthalmology subfields. The scientist's work emphasizes chemical synthesis and reactions, oxidative organic chemistry reactions, catalytic C-H functionalization methods, and catalytic cross-coupling reactions among other topics.

Recent publications by McDonald reflect work published from 2021 to 2024 in a variety of scientific journals. These include:

  • Fluorinated alcohols: powerful promoters for ring-opening reactions of epoxides with carbon nucleophiles, 2021, ARKIVOC
  • Stereospecific Cu(I)-Catalyzed C-O Cross-Coupling Synthesis of Acyclic 1,2-Di- and Trisubstituted Vinylic Ethers from Alcohols and Vinylic Halides, 2023, Organic Letters
  • A Tropomycin-Related Kinase B Receptor Activator for the Management of Ocular Blast-Induced Vision Loss, 2021, Journal of Neurotrauma
  • Ligand and Substrate Effects on Regio- and Stereoselective Ru(II)-Catalyzed Hydroacyloxylations to Vinylic Esters, 2024, Advanced Synthesis & Catalysis
  • Nontraditional Synthesis of Disaccharides via Acyclic Vinylic Ether Intermediates: Catalytic C-O Cross-Coupling as the Enabling Link, 2024, The Journal of Organic Chemistry

The scientist frequently collaborates with peers, including Micah A. Chrenek, San L. Pham, Tae-Hee Kim, P. Michael Iuvone, and Shweta Modgil. These partnerships contribute to a steady output in respected academic journals.

Publication venues where McDonald has appeared multiple times highlight a concentration in the following journals:

  • Organic Letters
  • ARKIVOC
  • Journal of Neurotrauma
  • Advanced Synthesis & Catalysis
  • The Journal of Organic Chemistry

McDonald's research integrates interdisciplinary approaches combining organic chemistry techniques with pharmaceutical science and molecular biology principles. This interdisciplinary approach supports advancements in areas such as chemical catalysis and biomedical applications.

Award recognition includes being named a Fellow of the Alfred P. Sloan Foundation in 1995, which indicates a measure of distinction in their scientific career.

Best Publications

  • Organolanthanide-Catalyzed Hydroamination/Cyclization. Efficient Allene-Based Transformations for the Syntheses of Naturally Occurring Alkaloids

    Victor M. Arredondo;Shun Tian;Frank E. McDonald;Tobin Jay Marks

  • Stereoselective Glycosylations of a Family of 6-Deoxy-1,2-glycals Generated by Catalytic Alkynol Cycloisomerization

    Frank E. McDonald;and K. Subba Reddy;Yolanda Díaz

  • Studies on tumor promoters. 9. A second-generation synthesis of phorbol

    Paul A. Wender;Frank E. McDonald

  • Organolanthanide-catalyzed intramolecular hydroamination/cyclization/bicyclization of sterically encumbered substrates. Scope, selectivity, and catalyst thermal stability for amine-tethered unactivated 1,2-disubstituted alkenes.

    Jae Sang Ryu;Tobin Jay Marks;Frank E. McDonald

  • Alkynol endo-Cycloisomerizations and Conceptually Related Transformations

    Frank E. McDonald

  • Organolanthanide-Catalyzed Intramolecular Hydroamination/Cyclization of Aminoallenes

    Victor M. Arredondo;Frank E. McDonald;Tobin Jay Marks

  • Intramolecular Hydroamination/Cyclization of Aminoallenes Catalyzed by Organolanthanide Complexes. Scope and Mechanistic Aspects

    Victor M. Arredondo;Frank E. McDonald;Tobin Jay Marks

  • Rhodium-Catalyzed Alkyne Cyclotrimerization Strategies for C-Aryl Glycoside Synthesis

    Frank E. McDonald;Hugh Y. H. Zhu;Christopher R. Holmquist

  • Asymmetric Synthesis of Nucleosides via Molybdenum-Catalyzed Alkynol Cycloisomerization Coupled with Stereoselective Glycosylations of Deoxyfuranose Glycals and 3-Amidofuranose Glycals

    Frank E. McDonald;Mark M. Gleason

  • Mechanism of Molybdenum Pentacarbonyl-Catalyzed Cyclizations of Alkynols and Epoxyalkynes

    Frank E. McDonald;Colleen C. Schultz

  • Organolanthanide-Catalyzed Intramolecular Hydroamination/Cyclization of Amines Tethered to 1,2-Disubstituted Alkenes

    Jae Sang Ryu;Tobin J. Marks;Frank E. McDonald

  • A new synthesis of 2,3-dihydrofurans : cycloisomerization of alkynyl alcohols to endocyclic enol ethers

    Frank E. McDonald;Colleen B. Connolly;Mark M. Gleason;Timothy B. Towne

  • Convergent Synthesis of Digitoxin: Stereoselective Synthesis and Glycosylation of the Digoxin Trisaccharide Glycal This research was supported by the U.S. National Institutes of Health (CA-59703). F.E.M. also thanks Novartis Pharmaceuticals for unrestricted additional funding (Grant Program for the Support of Academic Research in Synthetic Organic Chemistry).

    Frank E. McDonald;K. Subba Reddy

  • Total synthesis of the polyene-polyol macrolide RK-397, featuring cross-couplings of alkynylepoxide modules.

    Svetlana A. Burova;Frank E. Mcdonald

  • Group VI metal-promoted endo-azacyclizations via alkyne-derived metal vinylidene carbenes

    Frank E. McDonald;Arnab K. Chatterjee

  • Convergent Synthesis of Digitoxin: Stereoselective Synthesis and Glycosylation of the Digoxin Trisaccharide Glycal

    Frank E. McDonald;K. Subba Reddy

  • Application of Glycals to the Synthesis of Oligosaccharides: Convergent Total Syntheses of the Lewis X Trisaccharide Sialyl Lewis X Antigenic Determinant and Higher Congeners

    Samuel J. Danishefsky;Samuel J. Danishefsky;Jacquelyn Gervay;John M. Peterson;Frank E. McDonald

  • Synthesis of seven-membered ring glycals via endo-selective alkynol cycloisomerization.

    Eva Alcázar;Joseph M. Pletcher;Frank E. McDonald

  • syn-Oxidative Polycyclizations of Hydroxypolyenes: Highly Stereoselective and Potentially Biomimetic Syntheses of all-trans-Polytetrahydrofurans

    Timothy B. Towne;Frank E. McDonald

  • A stereoselective route from glycals to asparagine-linked N-protected glycopeptides

    Frank E. McDonald;Samuel J. Danishefsky

Frequent Co-Authors

Kenneth I. Hardcastle
Kenneth I. Hardcastle Emory University
Tobin J. Marks
Tobin J. Marks Northwestern University
Samuel J. Danishefsky
Samuel J. Danishefsky Columbia University
Paul A. Wender
Paul A. Wender Stanford University
P. Michael Iuvone
P. Michael Iuvone Emory University
Hongbo R. Luo
Hongbo R. Luo Boston Children's Hospital
Shi-Yong Sun
Shi-Yong Sun Emory University
Dennis C. Liotta
Dennis C. Liotta Emory University
Keqiang Ye
Keqiang Ye Shenzhen Institutes of Advanced Technology
Chi-Huey Wong
Chi-Huey Wong Scripps Research Institute

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