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Biology and Biochemistry
Italy
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
22942
World Ranking
3359
National Ranking
61

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Italy Leader Award

Overview

Antonello Mai is affiliated with Sapienza University of Rome in Italy. Their research primarily spans the broad fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these, their work focuses particularly on Molecular Biology, Epidemiology, Geriatrics and Gerontology, Oncology, and Physiology.

The main topics of their research include Histone Deacetylase Inhibitors Research, Epigenetics and DNA Methylation, Sirtuins and Resveratrol in Medicine, Protein Degradation and Inhibitors, Autophagy in Disease and Therapy, Cancer-related Gene Regulation, and Peptidase Inhibition and Analysis.

Antonello Mai has contributed extensively to scientific literature, with frequent publications in venues such as Journal of Medicinal Chemistry, ChemMedChem, bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Pharmacology, and Cancers. These venues reflect a focus on medicinal chemistry, pharmacology, and oncology-related fields.

Notable recent papers authored or co-authored by Antonello Mai include:

  • GreenMedChem: the challenge in the next decade toward eco-friendly compounds and processes in drug design, 2023, Green Chemistry
  • The Innovative Potential of Statins in Cancer: New Targets for New Therapies, 2020, Frontiers in Chemistry
  • LSD1 inhibitors for cancer treatment: Focus on multi-target agents and compounds in clinical trials, 2023, Frontiers in Pharmacology
  • Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression, 2021, Gastroenterology
  • A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action, 2020, Redox Biology

Frequent collaboration is a significant aspect of their work. Antonello Mai's most common co-authors include Dante Rotili, Sérgio Valente, Clemens Zwergel, Francesco Fiorentino, and Rossella Fioravanti. These collaborations suggest interdisciplinary and ongoing research partnerships.

Best Publications

  • Histone deacetylation in epigenetics: An attractive target for anticancer therapy

    Antonello Mai;Silvio Massa;Dante Rotili;Ilaria Cerbara

  • Correction: Corrigendum: Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma

    Sonia Coni;Anna Barbara Mancuso;Laura Di Magno;Giulia Sdruscia

  • TNF/p38α/Polycomb Signaling to Pax7 Locus in Satellite Cells Links Inflammation to the Epigenetic Control of Muscle Regeneration

    Daniela Palacios;Chiara Mozzetta;Silvia Consalvi;Giuseppina Caretti;Giuseppina Caretti

  • Sirtuin functions and modulation: from chemistry to the clinic.

    Vincenzo Carafa;Dante Rotili;Mariantonietta Forgione;Mariantonietta Forgione;Francesca Cuomo

  • BLUEPRINT to decode the epigenetic signature written in blood

    David Adams;Lucia Altucci;Stylionos E. Antonarakis;Juan Ballesteros

  • Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases LSD1 and LSD2

    Claudia Binda;Sergio Valente;Mauro Romanenghi;Simona Pilotto

  • SIRT5 regulation of ammonia-induced autophagy and mitophagy

    Lucia Polletta;Enza Vernucci;Ilaria Carnevale;Tania Arcangeli

  • Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect

    E Lara;A Mai;V Calvanese;L Altucci

  • HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment

    Claudia Colussi;Chiara Mozzetta;Aymone Gurtner;Barbara Illi

  • Epi-drugs to fight cancer: From chemistry to cancer treatment, the road ahead

    Antonello Mai;Lucia Altucci

  • Oxidative Stress and Epigenetic Regulation in Ageing and Age-Related Diseases

    Chiara Cencioni;Francesco Spallotta;Fabio Martelli;Sergio Valente

  • Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

    Andrea Galmozzi;Nico Mitro;Alessandra Ferrari;Elise Gers

  • The emerging role of epigenetics in human autoimmune disorders

    Roberta Mazzone;Roberta Mazzone;Clemens Zwergel;Marco Artico;Samanta Taurone

  • Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides.

    Antonello Mai;Silvio Massa;Riccardo Pezzi;Silvia Simeoni

  • Targeting Histone Demethylases A New Avenue for the Fight against Cancer

    Dante Rotili;Antonello Mai

  • Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (Sirtuin) inhibitors.

    Antonello Mai;Silvio Massa;Siva Lavu;Riccardo Pezzi

  • Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

    Jay H. Kalin;Jay H. Kalin;Muzhou Wu;Andrea V. Gomez;Yun Song

  • HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer

    Euan A Stronach;Albandri M Alfraidi;Nona R Rama;Christoph Datler

  • Inhibition of Histone Deacetylase Class I but not Class II Is Critical for the Sensitization of Leukemic Cells to Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Induced Apoptosis

    Satoshi Inoue;Antonello Mai;Martin J.S. Dyer;Gerald M. Cohen

  • Specific Control of Pancreatic Endocrine β- and δ-Cell Mass by Class IIa Histone Deacetylases HDAC4, HDAC5, and HDAC9

    Olivia Lenoir;Kathleen Flosseau;Feng Xia Ma;Bertrand Blondeau

Frequent Co-Authors

Dante Rotili
Dante Rotili Sapienza University of Rome
Sergio Valente
Sergio Valente Sapienza University of Rome
Lucia Altucci
Lucia Altucci University of Campania "Luigi Vanvitelli"
Marino Artico
Marino Artico Sapienza University of Rome
Saverio Minucci
Saverio Minucci European Institute of Oncology
Carlo Gaetano
Carlo Gaetano Goethe University Frankfurt
Andrea Mattevi
Andrea Mattevi University of Pavia
Ettore Novellino
Ettore Novellino University of Naples Federico II
Gerald Brosch
Gerald Brosch Innsbruck Medical University
Maurizio C. Capogrossi
Maurizio C. Capogrossi Johns Hopkins University

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