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Sergio Valente

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
9255
World Ranking
15206
National Ranking
476

Sergio Valente publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Sergio Valente sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 229 publications — 61st percentile

61% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Sergio Valente D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Sergio Valente sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 55 D-Index — 25th percentile

25% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Sergio Valente is affiliated with Sapienza University of Rome in Italy. Their research spans multiple fields within the life sciences, with a focus on biochemistry, genetics, molecular biology, and medicine.

Their work covers a broad range of topics including:

  • Histone Deacetylase Inhibitors Research
  • Epigenetics and DNA Methylation
  • Sirtuins and Resveratrol in Medicine
  • Protein Degradation and Inhibitors
  • Autophagy in Disease and Therapy
  • Peptidase Inhibition and Analysis
  • Cancer-related gene regulation

Valente's publications have appeared in various scientific journals. Frequent publication venues include:

  • Journal of Medicinal Chemistry
  • ChemMedChem
  • Frontiers in Pharmacology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • ACS Infectious Diseases

Their recent papers cover topics related to drug design, cancer therapies, and biochemical mechanisms, for example:

  • GreenMedChem: the challenge in the next decade toward eco-friendly compounds and processes in drug design, 2023, Green Chemistry
  • The Innovative Potential of Statins in Cancer: New Targets for New Therapies, 2020, Frontiers in Chemistry
  • Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression, 2021, Gastroenterology
  • A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action, 2020, Redox Biology
  • Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation, 2020, Science Advances

Frequent collaborators in Valente's research include:

  • Antonello Mai
  • Clemens Zwergel
  • Rossella Fioravanti
  • Dante Rotili
  • Elisabetta Di Bello

The scholar's main fields of study include Biochemistry, Genetics and Molecular Biology with 95 publications, followed by Medicine with 60 publications. Within these broader fields, subfields such as Molecular Biology, Epidemiology, Geriatrics and Gerontology, Immunology, and Oncology are represented in their work.

Best Publications

  • Histone deacetylation in epigenetics: An attractive target for anticancer therapy

    Antonello Mai;Silvio Massa;Dante Rotili;Ilaria Cerbara

  • TNF/p38α/Polycomb Signaling to Pax7 Locus in Satellite Cells Links Inflammation to the Epigenetic Control of Muscle Regeneration

    Daniela Palacios;Chiara Mozzetta;Silvia Consalvi;Giuseppina Caretti;Giuseppina Caretti

  • Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases LSD1 and LSD2

    Claudia Binda;Sergio Valente;Mauro Romanenghi;Simona Pilotto

  • Oxidative Stress and Epigenetic Regulation in Ageing and Age-Related Diseases

    Chiara Cencioni;Francesco Spallotta;Fabio Martelli;Sergio Valente

  • Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

    Andrea Galmozzi;Nico Mitro;Alessandra Ferrari;Elise Gers

  • Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

    Jay H. Kalin;Jay H. Kalin;Muzhou Wu;Andrea V. Gomez;Yun Song

  • Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC–MEF2 complexes

    Angela Nebbioso;Fabio Manzo;Marco Miceli;Mariarosaria Conte

  • Study of 1,4-Dihydropyridine Structural Scaffold: Discovery of Novel Sirtuin Activators and Inhibitors

    Antonello Mai;Sergio Valente;Sarah Meade;Vincenzo Carafa

  • epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors.

    Antonello Mai;Donghang Cheng;Mark T. Bedford;Sergio Valente

  • "Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence.

    Andrea Savarino;Antonello Mai;Sandro Norelli;Sary El Daker

  • Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities

    Dante Rotili;Stefano Tomassi;Mariarosaria Conte;Rosaria Benedetti

  • Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells.

    Sergio Valente;Yiwei Liu;Michael Schnekenburger;Clemens Zwergel

  • Nitric Oxide Modulates Chromatin Folding in Human Endothelial Cells via Protein Phosphatase 2A Activation and Class II Histone Deacetylases Nuclear Shuttling

    Barbara Illi;Claudio Dello Russo;Claudia Colussi;Jessica Rosati

  • Specific activity of class II histone deacetylases in human breast cancer cells.

    Vanessa Duong;Caroline Bret;Lucia Altucci;Antonello Mai

  • Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy.

    Roberta Mazzone;Roberta Mazzone;Clemens Zwergel;Antonello Mai;Sergio Valente

  • 1,3,4-Oxadiazole-containing histone deacetylase inhibitors: anticancer activities in cancer cells.

    Sergio Valente;Daniela Trisciuoglio;Teresa De Luca;Angela Nebbioso

  • Aurones: interesting natural and synthetic compounds with emerging biological potential.

    Clemens Zwergel;François Gaascht;Sergio Valente;Marc Diederich

  • A Nitric Oxide-dependent Cross-talk between Class I and III Histone Deacetylases Accelerates Skin Repair

    Francesco Spallotta;Chiara Cencioni;Stefania Straino;Simona Nanni

  • Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: Enzyme selectivity and cellular activity

    Donghang Cheng;Sergio Valente;Sabrina Castellano;Gianluca Sbardella

  • in human breast cancer cells

    Vanessa Duong;Caroline Bret;Lucia Altucci;Antonello Mai

Frequent Co-Authors

Antonello Mai
Antonello Mai Sapienza University of Rome
Lucia Altucci
Lucia Altucci University of Campania "Luigi Vanvitelli"
Dante Rotili
Dante Rotili Sapienza University of Rome
Saverio Minucci
Saverio Minucci European Institute of Oncology
Andrea Mattevi
Andrea Mattevi University of Pavia
Gilbert Kirsch
Gilbert Kirsch University of Lorraine
Gerald Brosch
Gerald Brosch Innsbruck Medical University
Carlo Gaetano
Carlo Gaetano Goethe University Frankfurt
Marc Diederich
Marc Diederich Seoul National University
Ettore Novellino
Ettore Novellino University of Naples Federico II

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Related Online Degrees & Career Pathways

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Best Scientists Citing Sergio Valente

Antonello Mai

Antonello Mai

Sapienza University of Rome

Publications: 84

Lucia Altucci

Lucia Altucci

University of Campania "Luigi Vanvitelli"

Publications: 57

Dante Rotili

Dante Rotili

Sapienza University of Rome

Publications: 41

Manfred Jung

Manfred Jung

University of Freiburg

Publications: 35

Saverio Minucci

Saverio Minucci

European Institute of Oncology

Publications: 34

Wolfgang Sippl

Wolfgang Sippl

Martin Luther University Halle-Wittenberg

Publications: 31

Takayoshi Suzuki

Takayoshi Suzuki

Osaka University

Publications: 30

Carlo Gaetano

Carlo Gaetano

Goethe University Frankfurt

Publications: 27

Philip A. Cole

Philip A. Cole

Brigham and Women's Hospital

Publications: 24

Andrea Mattevi

Andrea Mattevi

University of Pavia

Publications: 21

Hong-Min Liu

Hong-Min Liu

Zhengzhou University

Publications: 17

Maurizio C. Capogrossi

Maurizio C. Capogrossi

Johns Hopkins University

Publications: 17

José L. Medina-Franco

José L. Medina-Franco

National Autonomous University of Mexico

Publications: 15

Pier Lorenzo Puri

Pier Lorenzo Puri

Discovery Institute

Publications: 14

Michael A. Rudnicki

Michael A. Rudnicki

Ottawa Hospital Research Institute

Publications: 14

Marc Diederich

Marc Diederich

Seoul National University

Publications: 13

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