Joan X. Comella

Overview

Best Publications

• Sequential Treatment of SH‐SY5Y Cells with Retinoic Acid and Brain‐Derived Neurotrophic Factor Gives Rise to Fully Differentiated, Neurotrophic Factor‐Dependent, Human Neuron‐Like Cells

  Mario Encinas;Montse Iglesias;Yuhui Liu;Hongyin Wang

  1108
  Citations

• Extracellular-regulated kinases and phosphatidylinositol 3-kinase are involved in brain-derived neurotrophic factor-mediated survival and neuritogenesis of the neuroblastoma cell line SH-SY5Y.

  M. Encinas;M. Iglesias;N. Llecha;J. X. Comella

  361
  Citations

• Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation.

  Alessandra di Penta;Beatriz Moreno;Stephanie Reix;Begoña Fernandez-Diez

  265
  Citations

• Receptors of the glial cell line-derived neurotrophic factor family of neurotrophic factors signal cell survival through the phosphatidylinositol 3-kinase pathway in spinal cord motoneurons.

  Rosa M. Soler;Xavier Dolcet;Mario Encinas;Joaquim Egea

  250
  Citations

• Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease.

  Angela Gomez-Arboledas;Jose C. Davila;Elisabeth Sanchez-Mejias;Victoria Navarro

  231
  Citations

• A TrkB/EphrinA Interaction Controls Retinal Axon Branching and Synaptogenesis

  Katharine J. M. Marler;Elena Becker-Barroso;Albert Martínez;Marta Llovera

  200
  Citations

• Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12

  N Badiola;C Penas;C Penas;A Miñano-Molina;A Miñano-Molina;B Barneda-Zahonero;B Barneda-Zahonero

  198
  Citations

• c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway.

  Mario Encinas;Malú G. Tansey;Brian A. Tsui-Pierchala;Joan X. Comella

  192
  Citations

• Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function.

  Chris McDermott-Roe;Junmei Ye;Rizwan Ahmed;Xi-Ming Sun

  173
  Citations

• Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediate brain-derived neurotrophic factor-induced motoneuron survival.

  Xavier Dolcet;Joaquim Egea;Rosa M. Soler;Dionisio Martin‐Zanca

  167
  Citations

• Reactive Oxygen Species and p38 Mitogen-Activated Protein Kinase Activate Bax to Induce Mitochondrial Cytochrome c Release and Apoptosis in Response to Malonate

  M. Gomez-Lazaro;M. F. Galindo;R. M. Melero-Fernandez de Mera;F. J. Fernandez-Gómez

  165
  Citations

• 6-Hydroxydopamine activates the mitochondrial apoptosis pathway through p38 MAPK-mediated, p53-independent activation of Bax and PUMA.

  Maria Gomez-Lazaro;Maria F. Galindo;Caoimhín G. Concannon;Miguel F. Segura

  165
  Citations

• Terminal sprouting in mouse neuromuscular junctions poisoned with botulinum type a toxin: Morphological and electrophysiological features

  D. Angaut-Petit;J. Molgó;J.X. Comella;L. Faille

  155
  Citations

• Switch from Caspase-dependent to Caspase-independent Death during Heart Development ESSENTIAL ROLE OF ENDONUCLEASE G IN ISCHEMIA-INDUCED DNA PROCESSING OF DIFFERENTIATED CARDIOMYOCYTES

  Núria Bahi;Jisheng Zhang;Marta Llovera;Manel Ballester

  150
  Citations

• Proteasome Inhibitors Induce Death but Activate NF-κB on Endometrial Carcinoma Cell Lines and Primary Culture Explants

  Xavier Dolcet;David Llobet;Mario Encinas;Judit Pallares

  140
  Citations

• Cytokines promote motoneuron survival through the Janus kinase-dependent activation of the phosphatidylinositol 3-kinase pathway.

  Xavier Dolcet;Rosa M. Soler;Thomas W. Gould;Joaquim Egea

  131
  Citations

• Presynaptic actions of botulinal neurotoxins at vertebrate neuromuscular junctions.

  J. Molgo;J. X. Comella;D. Angaut-Petit;M. Pecot-Dechavassine

  129
  Citations

• PC12 cells have caveolae that contain TrkA. Caveolae-disrupting drugs inhibit nerve growth factor-induced, but not epidermal growth factor-induced, MAPK phosphorylation.

  Sandra Peiró;Joan X. Comella;Carlos Enrich;Dionisio Martı́n-Zanca

  129
  Citations

• Bcl-2 Is a Key Factor for Cardiac Fibroblast Resistance to Programmed Cell Death

  Maritza Mayorga;Núria Bahi;Manel Ballester;Joan X. Comella

  125
  Citations

• Nerve terminal sprouting in botulinum type-A treated mouse levator auris longus muscle

  Pascal Juzans;Joan X. Comella;Jordi Molgo;Lucette Faille

  121
  Citations