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Molecular Biology

D-Index
75
Citations
19140
World Ranking
1197
National Ranking
32

Overview

Hans Morreau is affiliated with the Leiden University Medical Center in the Netherlands. Their research spans several disciplines within medicine and biochemistry, genetics, and molecular biology.

Their main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, Morreau has contributed notably to subfields such as:

  • Oncology
  • Pathology and Forensic Medicine
  • Cancer Research
  • Molecular Biology
  • Endocrinology, Diabetes and Metabolism

Their research covers various topics related primarily to cancer and its genetic factors, with particular focus on colorectal cancer. The main topics of their work include:

  • Genetic factors in colorectal cancer
  • Cancer Genomics and Diagnostics
  • Colorectal Cancer Treatments and Studies
  • Colorectal Cancer Screening and Detection
  • Thyroid Cancer Diagnosis and Treatment
  • Pancreatic and Hepatic Oncology Research
  • Lung Cancer Treatments and Mutations

Morreau has published in multiple scientific venues. Among the frequent publication venues are:

  • Gastroenterology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Modern Pathology
  • Gut
  • Endocrine Related Cancer

Some recent papers attributed to this researcher include:

  • Patients with Rare Cancers in the Drug Rediscovery Protocol (DRUP) Benefit from Genomics-Guided Treatment, 2022, Clinical Cancer Research
  • Transcriptomic and immunophenotypic profiling reveals molecular and immunological hallmarks of colorectal cancer tumourigenesis, 2022, Gut
  • Surveillance for Pancreatic Cancer in High-Risk Individuals Leads to Improved Outcomes: A Propensity Score-Matched Analysis, 2023, Gastroenterology
  • Specific (sialyl-)Lewis core 2 O-glycans differentiate colorectal cancer from healthy colon epithelium, 2022, Theranostics
  • Mismatch repair deficiency is rare in bone and soft tissue tumors, 2021, Histopathology

The researcher frequently collaborates with others in the field, including:

  • Tom van Wezel
  • Maartje Nielsen
  • Monique E. van Leerdam
  • Diantha Terlouw
  • Carli M.J. Tops

Best Publications

  • HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome

    J.D. Carpten;C.M. Robbins;A. Villablanca;L. Forsberg

  • A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

    Ian P.M. Tomlinson;Emily Webb;Luis Carvajal-Carmona;Peter Broderick

  • Gene Expression Signature to Improve Prognosis Prediction of Stage II and III Colorectal Cancer

    Ramon Salazar;Paul Roepman;Gabriel Capella;Victor Moreno

  • Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance.

    Yvonne M C Hendriks;Anja Wagner;Hans Morreau;Fred Menko

  • Familial endometrial cancer in female carriers of MSH6 germline mutations

    J Wijnen;W de Leeuw;H Vasen;H van der Klift

  • Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence

    G. Weeda;I. Donker;J. de Wit;H. Morreau

  • The carcinoma–stromal ratio of colon carcinoma is an independent factor for survival compared to lymph node status and tumor stage

    Wilma E. Mesker;Jan M. C. Junggeburt;Karoly Szuhai;Pieter de Heer

  • Defective Transcription-Coupled Repair in Cockayne Syndrome B Mice Is Associated with Skin Cancer Predisposition

    Gijsbertus T.J van der Horst;Harry van Steeg;Rob J.W Berg;Alain J van Gool

  • Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers

    Hans Vasen;Isaura Ibrahim;Carmen Guillen Ponce;Emily P. Slater

  • Microsatellite Instability, Immunohistochemistry, and Additional PMS2 Staining in Suspected Hereditary Nonpolyposis Colorectal Cancer

    Andrea E. de Jong;Marjo van Puijenbroek;Yvonne Hendriks;Carli Tops

  • Molecular Analysis of Hereditary Nonpolyposis Colorectal Cancer in the United States: High Mutation Detection Rate among Clinically Selected Families and Characterization of an American Founder Genomic Deletion of the MSH2 Gene

    Anja Wagner;Alicia Barrows;Juul Th. Wijnen;Heleen van der Klift

  • Immune system and prognosis in colorectal cancer: a detailed immunohistochemical analysis

    Anand G Menon;Connie M Janssen van Rhijn;Hans Morreau;Hein Putter

  • Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study

    Enric Domingo;Enric Domingo;Luke Freeman-Mills;Emily Rayner;Mark Glaire

  • Detection of colorectal polyps in humans using an intravenously administered fluorescent peptide targeted against c-Met

    Jacobus Burggraaf;Ingrid M C Kamerling;Paul B Gordon;Lenneke Schrier

  • Prediction of a mismatch repair gene defect by microsatellite instability and immunohistochemical analysis in endometrial tumours from HNPCC patients

    Wiljo J. F. de Leeuw;Wiljo J. F. de Leeuw;JanWillem Dierssen;Hans F. A. Vasen;Juul Th. Wijnen

  • Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumors.

    Yvonne Hendriks;Patrick Franken;Jan Willem Dierssen;Wiljo de Leeuw

  • The role of mismatch repair gene defects in the development of adenomas in patients with HNPCC.

    Andrea E. De Jong;Hans Morreau;Marjo Van Puijenbroek;Paul H.C. Eilers

  • A Mouse Model for the Basal Transcription/DNA Repair Syndrome Trichothiodystrophy

    Jan de Boer;Jan de Wit;Harry van Steeg;Rob J.W. Berg

  • Prognostic Value of Tumor-Infiltrating Dendritic Cells in Colorectal Cancer: Role of Maturation Status and Intratumoral Localization

    Maro H. Sandel;Alisher R. Dadabayev;Anand G. Menon;Hans Morreau

  • Atypical HNPCC owing to MSH6 germline mutations: analysis of a large Dutch pedigree

    A Wagner;Y Hendriks;E J Meijers-Heijboer;W J F de Leeuw

Frequent Co-Authors

Tom van Wezel
Tom van Wezel Leiden University Medical Center
Hans F. A. Vasen
Hans F. A. Vasen Leiden University
Frederik J. Hes
Frederik J. Hes Vrije Universiteit Brussel
Juul T. Wijnen
Juul T. Wijnen Leiden University Medical Center
Cornelis J.H. van de Velde
Cornelis J.H. van de Velde Leiden University Medical Center
Rob A. E. M. Tollenaar
Rob A. E. M. Tollenaar Leiden University Medical Center
Riccardo Fodde
Riccardo Fodde Erasmus MC
Cees J. Cornelisse
Cees J. Cornelisse Leiden University Medical Center
Hein Putter
Hein Putter Leiden University Medical Center
Gert Jan Fleuren
Gert Jan Fleuren Leiden University Medical Center

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