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Medicine

D-Index
142
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81780
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1554
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Research.com Recognitions

  • 2006 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Gynaecology and Paediatrics

Overview

Franco Locatelli is affiliated with the Catholic University of the Sacred Heart in Italy. Their research spans across medicine and the intersecting fields of biochemistry, genetics, and molecular biology. Within these disciplines, their work notably addresses subfields including hematology, immunology, genetics, molecular biology, and public health.

Their research concentrates on several main topics, such as:

  • Acute Lymphoblastic Leukemia research
  • Hematopoietic Stem Cell Transplantation
  • CAR-T cell therapy research
  • Acute Myeloid Leukemia Research
  • Immune Cell Function and Interaction
  • Hemoglobinopathies and Related Disorders
  • Chronic Myeloid Leukemia Treatments

Franco Locatelli has contributed to numerous scientific publications, with frequent venues including:

  • Blood
  • Bone Marrow Transplantation
  • Blood Advances
  • Transplantation and Cellular Therapy
  • Frontiers in Immunology

Among their recent papers are:

  • "Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis," 2020, New England Journal of Medicine
  • "CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia," 2020, New England Journal of Medicine
  • "Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study," 2020, The Lancet Respiratory Medicine
  • "Ruxolitinib for Glucocorticoid-Refractory Chronic Graft-versus-Host Disease," 2021, New England Journal of Medicine
  • "GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma," 2023, New England Journal of Medicine

Frequent co-authors collaborating with Locatelli include:

  • Pietro Merli
  • Angela Mastronuzzi
  • Concetta Quintarelli
  • Francesca Del Bufalo
  • Mattia Algeri

In 2006, Locatelli received recognition from the German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina - Nationale Akademie der Wissenschaften in the field of Gynaecology and Paediatrics.

Best Publications

  • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study.

    Katarina Le Blanc;Francesco Frassoni;Lynne Ball;Franco Locatelli

  • OUTCOME OF CORD-BLOOD TRANSPLANTATION FROM RELATED AND UNRELATED DONORS

    Eliane Gluckman;Vanderson Rocha;Agnes Boyer-Chammard;Franco Locatelli

  • CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia

    Haydar Frangoul;David Altshuler;M. Domenica Cappellini;Yi-Shan Chen

  • Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemia.

    Vanderson Rocha;Jacqueline Cornish;Eric L. Sievers;Alexandra Filipovich

  • Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study

    Valentino Conter;Claus R. Bartram;Maria Grazia Valsecchi;Andre Schrauder

  • Human bone marrow derived mesenchymal stem cells do not undergo transformation after long-term in vitro culture and do not exhibit telomere maintenance mechanisms.

    Maria Ester Bernardo;Nadia Zaffaroni;Francesca Novara;Angela Maria Cometa

  • Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotype

    Rita Maccario;Marina Podestà;Antonia Moretta;Angela Cometa

  • Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation.

    Lynne M. Ball;Maria Ester Bernardo;Helene Roelofs;Arjan Lankester

  • Survival advantage with KIR ligand incompatibility in hematopoietic stem cell transplantation from unrelated donors

    Sebastian Giebel;Franco W Locatelli;Teresa Lamparelli;Andrea Velardi

  • International, Multicenter Standardization of Acute Graft-versus-Host Disease Clinical Data Collection: A Report from the Mount Sinai Acute GVHD International Consortium.

    Andrew C. Harris;Andrew C. Harris;Rachel Young;Rachel Young;Steven Devine;William J. Hogan

  • Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease

    Rachele Ciccocioppo;Maria Ester Bernardo;Adele Sgarella;Rita Maccario

  • Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study.

    Giacomo Grasselli;Giacomo Grasselli;Tommaso Tonetti;Alessandro Protti;Thomas Langer

  • Phase I/Phase II Study of Blinatumomab in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia

    Arend von Stackelberg;Franco Locatelli;Gerhard Zugmaier;Rupert Handgretinger

  • Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study

    Martin Schrappe;Maria Grazia Valsecchi;Claus R. Bartram;André Schrauder

  • Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity

    Daniela Pende;Stefania Marcenaro;Michela Falco;Stefania Martini

  • Chronic myelomonocytic leukemia in childhood. A retrospective analysis of 110 cases.

    C.M. Niemeyer;M. Aricó;G. Basso;A. Biondi

  • Factors associated with outcomes of unrelated cord blood transplant: Guidelines for donor choice

    Eliane Gluckman;Vanderson Rocha;William Arcese;Gérard Michel

  • Related umbilical cord blood transplantation in patients with thalassemia and sickle cell disease

    Franco Locatelli;Vanderson Rocha;William Reed;Françoise Bernaudin

  • HLA-haploidentical stem cell transplantation after removal of αβ+ T and B cells in children with nonmalignant disorders

    Alice Bertaina;Pietro Merli;Sergio Rutella;Sergio Rutella;Daria Pagliara

  • Sickle cell disease: an international survey of results of HLA-identical sibling hematopoietic stem cell transplantation

    Eliane Gluckman;Barbara Cappelli;Francoise Bernaudin;Myriam Labopin

Frequent Co-Authors

Francesco Cecconi
Francesco Cecconi Catholic University of the Sacred Heart
Peter Bader
Peter Bader Goethe University Frankfurt
Andrea Biondi
Andrea Biondi University of Milano-Bicocca
Henrik Hasle
Henrik Hasle Aarhus University Hospital
Marco Zecca
Marco Zecca University of Pavia
Charlotte M. Niemeyer
Charlotte M. Niemeyer University of Freiburg
Maria Grazia Valsecchi
Maria Grazia Valsecchi University of Milano-Bicocca
Michael Dworzak
Michael Dworzak Medical University of Vienna
Franca Fagioli
Franca Fagioli University of Turin
Alice Bertaina
Alice Bertaina Stanford University

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