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Genetics

D-Index
64
Citations
15823
World Ranking
2784
National Ranking
1221

Overview

Sen Pathak is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research focus lies primarily within Biochemistry, Genetics, and Molecular Biology, with a strong emphasis on Genetics and Molecular Biology subfields. Additional areas of study include Plant Science, Immunology, and Oncology.

Their recent publications cover a range of topics tied closely to genomic structures, genetic diversity, and molecular mechanisms. Key published works include:

  • 3D genomics across the tree of life reveals condensin II as a determinant of architecture type (2021, Science)
  • Mutant p53 gains oncogenic functions through a chromosomal instability-induced cytosolic DNA response (2024, Nature Communications)
  • Chromosome size affects sequence divergence between species through the interplay of recombination and selection (2022, Evolution)
  • Chromosome size affects sequence divergence between species through the interplay of recombination and selection (2021, bioRxiv [Cold Spring Harbor Laboratory])
  • The Role of Molecular Docking in Modern Drug Discovery and Development: A Comprehensive Review (2024, Journal of Drug Discovery and Health Sciences)

Their research topics span several areas, including:

  • Genomics and Phylogenetic Studies
  • Genetic diversity and population structure
  • Genetic Mapping and Diversity in Plants and Animals
  • Chromosomal and Genetic Variations
  • RNA and protein synthesis mechanisms
  • Interferon and immune responses
  • Ubiquitin and proteasome pathways

Pathak has collaborated frequently with several researchers in their field. The most common co-authors include Asha S. Multani, Olga Dudchenko, David Weisz, Arina D. Omer, and Ruqayya Khan.

Their scholarly output has been published repeatedly in venues such as Archives of Clinical Neuropsychology, Science, Nature Communications, Evolution, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • Androgen-independent cancer progression and bone metastasis in the LNCaP model of human prostate cancer.

    George N. Thalmann;Ploutarchos E. Anezinis;Shi Ming Chang;Haiyen E. Zhau

  • Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: Role of bone stromal cells

    Hsi‐Chin ‐C Wu;Jer‐Tsong ‐T Hsieh;Martin E. Gleave;Nicholas M. Brown

  • Essential role of limiting telomeres in the pathogenesis of Werner syndrome.

    Sandy Chang;Asha S Multani;Noelia G Cabrera;Maria L Naylor

  • Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres.

    Ling Wu;Asha S. Multani;Hua He;Wilfredo Cosme-Blanco

  • Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice.

    Curtis A. Pettaway;Sen Pathak;Graham Greene;Edilberto Ramirez

  • LNCaP progression model of human prostate cancer: androgen-independence and osseous metastasis.

    George N. Thalmann;Robert A. Sikes;Tony T. Wu;Armelle Degeorges

  • Familial renal cell carcinoma with a 3 ; 11 chromosome translocation limited to tumor cells

    S. Pathak;Louise C Strong;R. E. Ferrell;A. Trindade

  • Spontaneous Abnormalities in Normal Fibroblasts from Patients with Li-Fraumeni Cancer Syndrome: Aneuploidy and Immortalization

    Farideh Z. Bischoff;Sun O. Yim;Sen Pathak;Grace Grant

  • ANDROGEN-REPRESSED PHENOTYPE IN HUMAN PROSTATE CANCER

    Hai Yen E. Zhau;Shi-Ming Chang;Bao-Qi Chen;Yunling Wang

  • Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53‐dependent cellular senescence

    Wilfredo Cosme-Blanco;Mei Feng Shen;Alexander J.F. Lazar;Sen Pathak

  • Nonrandom loss of maternal chromosome 11 alleles in Wilms' tumors

    W. T. Schroeder;L. Y. Chao;D. D. Dao;Louise C Strong

  • Plasma Cell Karyotype in Multiple Myeloma

    James Gould;Raymond Alexanian;Angela Goodacre;Sen Pathak

  • Establishment and Characterization of Two New Squamous Cell Carcinoma Cell Lines Derived from Tumors of the Head and Neck

    Peter G. Sacks;Steven M. Parnes;Gary E. Gallick;Zahra Mansouri

  • Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway

    Purnima R. Laud;Asha S. Multani;Susan M. Bailey;Ling Wu

  • Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells.

    Tej K. Pandita;S. Pathak;C. R. Geard

  • Tumor-specific low molecular weight forms of cyclin E induce genomic instability and resistance to p21, p27, and antiestrogens in breast cancer.

    Said Akli;Ping Ju Zheng;Asha S. Multani;Hannah F. Wingate;Hannah F. Wingate

  • Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA.

    Jiang Shou;Francis Ali-Osman;Asha S Multani;Sen Pathak

  • Effects of ethidium bromide on mitosis and chromosomes: a possible material basis for chromosome stickiness.

    Manley McGill;Manley McGill;Sen Pathak;Sen Pathak;T. C. Hsu;T. C. Hsu

  • Isolation and Characterization of Metastatic Variants from Human Transitional Cell Carcinoma Passaged by Orthotopic Implantation in Athymic Nude Mice

    Colin P. N. Dinney;Randi Fishbeck;Rakesh K. Singh;Beryl Eve

  • Involvement of Chromosome 7 in Primary Lung Tumor and Nonmalignant Normal Lung Tissue

    Jin S. Lee;Sen Pathak;Vicki Hopwood;Barbara Tomasovic

Frequent Co-Authors

Asha S. Multani
Asha S. Multani The University of Texas MD Anderson Cancer Center
Leland W.K. Chung
Leland W.K. Chung Cedars-Sinai Medical Center
Isaiah J. Fidler
Isaiah J. Fidler The University of Texas MD Anderson Cancer Center
Sandy Chang
Sandy Chang Yale University
Haiyen E. Zhau
Haiyen E. Zhau Cedars-Sinai Medical Center
Dennis A. Johnston
Dennis A. Johnston Baylor University
Kapil Mehta
Kapil Mehta MolQ Laboratory
Margaret R. Spitz
Margaret R. Spitz Baylor College of Medicine
Fredrick B. Hagemeister
Fredrick B. Hagemeister The University of Texas MD Anderson Cancer Center
Robert A. Newman
Robert A. Newman The University of Texas MD Anderson Cancer Center

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