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Raphael Margueron

Raphael Margueron

D-Index & Metrics

Molecular Biology

D-Index
53
Citations
17388
World Ranking
2359
National Ranking
88

Overview

Raphael Margueron is affiliated with Grenoble Alpes University in France. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with significant work in Molecular Biology, Plant Science, Neurology, Genetics, and Oncology.

The main topics covered in their research include:

  • Epigenetics and DNA Methylation
  • Genomics and Chromatin Dynamics
  • RNA modifications and cancer
  • Chromosomal and Genetic Variations
  • Cancer-related gene regulation
  • Ubiquitin and proteasome pathways
  • DNA Repair Mechanisms

Among the frequent publication venues where Raphael Margueron's work appears are Zenodo (CERN European Organization for Nuclear Research), Cancer Research, Nature Communications, The American Journal of Human Genetics, and Methods in Molecular Biology.

Their recent papers include:

  • PBRM1 Deficiency Confers Synthetic Lethality to DNA Repair Inhibitors in Cancer, 2021, Cancer Research
  • A cis-acting mechanism mediates transcriptional memory at Polycomb target genes in mammals, 2021, Nature Genetics
  • Succinylation of H3K122 destabilizes nucleosomes and enhances transcription, 2021, EMBO Reports
  • XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation, 2022, Cell
  • Paramecium Polycomb repressive complex 2 physically interacts with the small RNA-binding PIWI protein to repress transposable elements, 2022, Developmental Cell

Raphael Margueron has collaborated frequently with several researchers, including:

  • Daniel Holoch
  • Michel Wassef
  • Audrey Michaud
  • Setareh Aflaki
  • Laia Richart

Best Publications

  • The Polycomb complex PRC2 and its mark in life

    Raphaël Margueron;Danny Reinberg

  • Role of the polycomb protein EED in the propagation of repressive histone marks

    Raphael Margueron;Neil Justin;Katsuhito Ohno;Miriam L. Sharpe

  • The key to development: interpreting the histone code?

    Raphael Margueron;Patrick Trojer;Danny Reinberg

  • Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms.

    Raphael Margueron;Guohong Li;Kavitha Sarma;Alexandre Blais

  • Chromatin Structure and the Inheritance of Epigenetic Information

    Raphaël Margueron;Danny Reinberg

  • Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27

    Antonis Kirmizis;Stephanie M. Bartley;Andrei Kuzmichev;Raphael Margueron

  • Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation.

    Andrei Kuzmichev;Raphael Margueron;Alejandro Vaquero;Tanja S. Preissner

  • Jarid2 and PRC2, partners in regulating gene expression

    Gang Li;Raphael Margueron;Manching Ku;Pierre Chambon

  • Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA

    Syuzo Kaneko;Gang Li;Jinsook Son;Chong-Feng Xu

  • Suz12 binds to silenced regions of the genome in a cell-type-specific manner

    Sharon L. Squazzo;Henriette O'Geen;Vitalina M. Komashko;Sheryl R. Krig

  • Prdm3 and Prdm16 are H3K9me1 Methyltransferases Required for Mammalian Heterochromatin Integrity

    Inês Pinheiro;Raphaël Margueron;Nicholas Shukeir;Michael Eisold

  • Ezh2 Requires PHF1 To Efficiently Catalyze H3 Lysine 27 Trimethylation In Vivo

    Kavitha Sarma;Raphael Margueron;Alexey Ivanov;Vincenzo Pirrotta

  • The Histone H3 Lysine 9 Methyltransferases G9a and GLP Regulate Polycomb Repressive Complex 2-Mediated Gene Silencing

    Chiara Mozzetta;Julien Pontis;Lauriane Fritsch;Philippe Robin

  • Legionella pneumophila effector RomA uniquely modifies host chromatin to repress gene expression and promote intracellular bacterial replication.

    Monica Rolando;Serena Sanulli;Serena Sanulli;Serena Sanulli;Christophe Rusniok;Christophe Rusniok;Laura Gomez-Valero;Laura Gomez-Valero

  • Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation

    Serena Sanulli;Serena Sanulli;Serena Sanulli;Neil Justin;Aurélie Teissandier;Aurélie Teissandier;Aurélie Teissandier;Katia Ancelin;Katia Ancelin;Katia Ancelin

  • Regulation of Transcription through Acetylation of H3K122 on the Lateral Surface of the Histone Octamer

    Philipp Tropberger;Sebastian Pott;Claudia Keller;Claudia Keller;Kinga Kamieniarz-Gdula

  • Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome

    Simão Teixeira da Rocha;Valentina Boeva;Martin Escamilla-Del-Arenal;Katia Ancelin

  • Mechanisms Regulating PRC2 Recruitment and Enzymatic Activity

    Daniel Holoch;Daniel Holoch;Raphaël Margueron;Raphaël Margueron

  • Circadian Expression of the Steroid 15 α-Hydroxylase (Cyp2a4) and Coumarin 7-Hydroxylase (Cyp2a5) Genes in Mouse Liver Is Regulated by the PAR Leucine Zipper Transcription Factor DBP

    Daniel J. Lavery;Luis Lopez-Molina;Raphael Margueron;Fabienne Fleury-Olela

  • EZH2 and Histone 3 Trimethyl Lysine 27 Associated with Il4 and Il13 Gene Silencing in TH1 Cells

    Madoka Koyanagi;Aurelie Baguet;Joost Martens;Raphael Margueron

Frequent Co-Authors

Danny Reinberg
Danny Reinberg University of Miami
Vincent Cavaillès
Vincent Cavaillès Institute of Cancer Research of Montpellier
Damarys Loew
Damarys Loew PSL University
Edith Heard
Edith Heard Collège de France
Michiel Vermeulen
Michiel Vermeulen Radboud University
Peggy J. Farnham
Peggy J. Farnham University of Southern California
Geneviève Almouzni
Geneviève Almouzni Institute Curie
Carmen Buchrieser
Carmen Buchrieser Institut Pasteur
Thomas Jenuwein
Thomas Jenuwein Max Planck Society
Diego Pasini
Diego Pasini European Institute of Oncology

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