Christopher C. J. Miller

Overview

Best Publications

• TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

  Jemeen Sreedharan;Ian P. Blair;Vineeta B. Tripathi;Xun Hu

  2948
  Citations

• Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

  Caroline Vance;Boris Rogelj;Tibor Hortobágyi;Kurt J. De Vos

  2898
  Citations

• Role of Axonal Transport in Neurodegenerative Diseases

  Kurt J. De Vos;Andrew J. Grierson;Steven Ackerley;Christopher C. J. Miller

  867
  Citations

• Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study

  M R Turner;A Cagnin;F E Turkheimer;F E Turkheimer;Christopher Miller

  856
  Citations

• ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

  Radu Stoica;Kurt J. De Vos;Kurt J. De Vos;Sébastien Paillusson;Sarah Mueller

  652
  Citations

• Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells

  S Lovestone;C H Reynolds;D Latimer;Davis

  644
  Citations

• VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

  Kurt J. De Vos;Gábor M. Mórotz;Radu Stoica;Elizabeth L. Tudor

  511
  Citations

• The importance of tau phosphorylation for neurodegenerative diseases.

  Wendy Noble;Diane P. Hanger;Christopher C. J. Miller;Simon Lovestone

  505
  Citations

• Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content

  Kurt J. De Vos;Kurt J. De Vos;Anna L. Chapman;Maria E. Tennant;Catherine Manser

  473
  Citations

• There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases

  Sebastien Paillusson;Radu Stoica;Patricia Gomez-Suaga;Dawn H.W. Lau

  426
  Citations

• α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca 2+ homeostasis and mitochondrial ATP production

  Sébastien Paillusson;Patricia Gomez-Suaga;Radu Stoica;Daniel Little

  368
  Citations

• Cellular phosphorylation of tau by GSK-3 beta influences tau binding to microtubules and microtubule organisation

  Uta Wagner;Michelle Utton;Jean-Marc Gallo;Christopher C. J. Miller

  351
  Citations

• The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy

  Patricia Gomez-Suaga;Sebastien Paillusson;Radu Stoica;Wendy Noble

  345
  Citations

• Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion

  Jacqueline C. Mitchell;Philip McGoldrick;Caroline Vance;Tibor Hortobagyi

  298
  Citations

• ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules

  Caroline Vance;Emma L. Scotter;Agnes L. Nishimura;Claire Troakes

  280
  Citations

• Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations

  Vinay K. Godena;Nicholas Brookes-Hocking;Annekathrin Moller;Gary Shaw

  272
  Citations

• Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport

  Janet Brownlees;Steven Ackerley;Andrew J. Grierson;Nick J.O. Jacobsen

  258
  Citations

• ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB–PTPIP51 interaction and ER–mitochondria associations

  Radu Stoica;Sébastien Paillusson;Patricia Gomez‐Suaga;Jacqueline C Mitchell

  251
  Citations

• Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments

  Steven Ackerley;Paul Thornhill;Andrew J. Grierson;Janet Brownlees

  250
  Citations

• Supporting Online Material for Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

  Caroline Vance;Boris Rogelj;Tibor Hortobágyi;Kurt J. De Vos

  3
  Citations