Brian H. Anderton

Research.com Recognitions

• Fellow of The Academy of Medical Sciences, United Kingdom
• Fellow of The Academy of Medical Sciences, United Kingdom
• Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Best Publications

• Tau phosphorylation: the therapeutic challenge for neurodegenerative disease.

  Diane P. Hanger;Brian H. Anderton;Wendy Noble

  1148
  Citations

• Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase.

  Diane P. Hanger;Kenneth Hughes;James R. Woodgett;Jean-Pierre Brion

  928
  Citations

• All classes of intermediate filaments share a common antigenic determinant defined by a monoclonal antibody

  Rebecca M. Pruss;Rhona Mirsky;Martin C. Raff;Robin Thorpe

  831
  Citations

• Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants

  BH Anderton;D Breinburg;MJ Downes;PJ Green

  674
  Citations

• Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells

  S Lovestone;C H Reynolds;D Latimer;Davis

  644
  Citations

• Novel Phosphorylation Sites in Tau from Alzheimer Brain Support a Role for Casein Kinase 1 in Disease Pathogenesis

  Diane P. Hanger;Helen L. Byers;Selina Wray;Kit-Yi Leung

  527
  Citations

• Phosphorylation Sites on Tau Identified by Nanoelectrospray Mass Spectrometry

  C H Reynolds;J C Betts;W P Blackstock;A R Nebreda

  518
  Citations

• New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry.

  Diane P. Hanger;Joanna C. Betts;Thérèse L. F. Loviny;Walter P. Blackstock

  476
  Citations

• Glycogen synthase kinase-3 inhibition is integral to long-term potentiation.

  Claudie Hooper;V Markevich;Florian Plattner;Richard Killick

  420
  Citations

• Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity.

  P. N. Leigh;H. Whitwell;O. Garofalo;J. Buller

  409
  Citations

• Monoclonal antibodies to mammalian neurofilaments

  John N. Wood;Brian H. Anderton

  382
  Citations

• Ubiquitin deposits in anterior horn cells in motor neurone disease

  P.N. Leigh;B.H. Anderton;A. Dodson;J.-M. Gallo

  358
  Citations

• Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion.

  K. C. Breen;M. Bruce;B. H. Anderton

  347
  Citations

• Stress‐Activated Protein Kinase/c‐Jun N‐Terminal Kinase Phosphorylates τ Protein

  C H Reynolds;M A Utton;G M Gibb;A Yates

  314
  Citations

• Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: involvement of Src family protein kinases.

  Ritchie Williamson;Timothy Scales;Bruce R. Clark;Graham Gibb

  291
  Citations

• Phosphorylation of tau by glycogen synthase kinase-3 beta in intact mammalian cells: the effects on the organization and stability of microtubules.

  S. Lovestone;C.L. Hartley;J. Pearce;B.H. Anderton

  285
  Citations

• Phosphorylation Regulates Tau Interactions with Src Homology 3 Domains of Phosphatidylinositol 3-Kinase, Phospholipase Cγ1, Grb2, and Src Family Kinases

  C. Hugh Reynolds;Claire J. Garwood;Selina Wray;Caroline Price

  283
  Citations

• Hippocampal and neocortical ubiquitin-immunoreactive inclusions in amyotrophic lateral sclerosis with dementia.

  G. Wightman;V.E.R. Anderson;J. Martin;M. Swash

  277
  Citations

• In Vitro Phosphorylation of the Cytoplasmic Domain of the Amyloid Precursor Protein by Glycogen Synthase Kinase‐3β

  Aplin Ae;Gibb Gm;Jacobsen Js;Gallo Jm

  266
  Citations

• Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport

  Janet Brownlees;Steven Ackerley;Andrew J. Grierson;Nick J.O. Jacobsen

  258
  Citations