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Biology and Biochemistry

D-Index
47
Citations
14877
World Ranking
18557
National Ranking
7582

Overview

Richard L. Klemke is affiliated with the University of California, San Diego in the United States. Their research spans several fields related to physics and earth sciences, with a notable focus on both fundamental and applied aspects of these disciplines.

Their primary fields of study include:

  • Physics and Astronomy
  • Earth and Planetary Sciences

Within these broader fields, Klemke's work covers several subfields such as:

  • Astronomy and Astrophysics
  • Oceanography
  • Environmental Chemistry
  • Nuclear and High Energy Physics
  • Geophysics

The scientist's main topics of research focus on:

  • Ionosphere and magnetosphere dynamics
  • Geophysics and Gravity Measurements
  • Methane Hydrates and Related Phenomena
  • Solar and Space Plasma Dynamics
  • Astrophysics and Cosmic Phenomena
  • Seismic Waves and Analysis
  • Earthquake Detection and Analysis

Klemke has contributed frequently to the following publication venues, indicating a broad research output spanning multiple aspects of physics and related sciences:

  • OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)
  • Cancer Research
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Data in Brief
  • Nature Biomedical Engineering

Among recent publications, several notable papers include:

  • Genetically engineered and enucleated human mesenchymal stromal cells for the targeted delivery of therapeutics to diseased tissue, 2021, Nature Biomedical Engineering
  • Bladder Cancer Invasion Is Mediated by Mammalian Target of Rapamycin Complex 2-Driven Regulation of Nitric Oxide and Invadopodia Formation, 2021, American Journal Of Pathology
  • Breast cancer stem cells tolerate chromosomal instability during tumor progression via c-Jun/AXL stress signaling, 2023, Heliyon
  • The Heparan Sulfate Binding Peptide in Tumor Progression of Triple-Negative Breast Cancer, 2021, Frontiers in Oncology
  • S100A8/A9 innate immune signaling as a distinct mechanism driving progression of smoking-related breast cancers, 2025, Oncogene

The frequent co-authors working with Richard L. Klemke include:

  • Jon Jacobs
  • Ashley Robinson
  • Keqi Tang
  • Ljiljana Paša-Tolić
  • Desmond Smith

Best Publications

  • Regulation of Cell Motility by Mitogen-activated Protein Kinase

    Richard L. Klemke;Shuang Cai;Ana L. Giannini;Patricia J. Gallagher

  • Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin.

    Peter C. Brooks;Staffan Strömblad;Richard Klemke;Daniel Visscher

  • Spatiotemporal dynamics of RhoA activity in migrating cells

    Olivier Pertz;Olivier Pertz;Olivier Pertz;Louis Hodgson;Louis Hodgson;Louis Hodgson;Richard L. Klemke;Richard L. Klemke;Klaus M. Hahn;Klaus M. Hahn;Klaus M. Hahn

  • CAS/Crk Coupling Serves as a “Molecular Switch” for Induction of Cell Migration

    Richard L. Klemke;Jie Leng;Rachel Molander;Peter C. Brooks

  • Reversed‐phase chromatography with multiple fraction concatenation strategy for proteome profiling of human MCF10A cells

    Yuexi Wang;Feng Yang;Marina A. Gritsenko;Yingchun Wang

  • Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells.

    Alice Y. Ting;Kristin H. Kain;Richard L. Klemke;Roger Y. Tsien

  • Integrin αvβ3 Requirement for Sustained Mitogen-activated Protein Kinase Activity during Angiogenesis.

    B P Eliceiri;R Klemke;S Strömblad;D A Cheresh

  • High-resolution imaging of the dynamic tumor cell vascular interface in transparent zebrafish.

    Konstantin Stoletov;Valerie Montel;Robin D. Lester;Steven L. Gonias

  • Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin.

    Richard L. Klemke;Mayra Yebra;Evelyn M. Bayna;David A. Cheresh

  • Visualizing extravasation dynamics of metastatic tumor cells.

    Konstantin Stoletov;Hisashi Kato;Erin Zardouzian;Jonathan Kelber

  • Four Human Ras Homologs Differ in Their Abilities to Activate Raf-1, Induce Transformation, and Stimulate Cell Motility

    Julia K. Voice;Richard L. Klemke;Ann Le;Janis H. Jackson

  • Extracellular-Regulated Kinase Activation and Cas/Crk Coupling Regulate Cell Migration and Suppress Apoptosis during Invasion of the Extracellular Matrix

    Samuel Y. Cho;Richard L. Klemke

  • Regulation of Cell Contraction and Membrane Ruffling by Distinct Signals in Migratory Cells

    David A. Cheresh;Jie Leng;Richard L. Klemke

  • Adenovirus endocytosis via alpha(v) integrins requires phosphoinositide-3-OH kinase.

    Erguang Li;Dwayne Stupack;Richard Klemke;David A. Cheresh

  • Vascular Lipid Accumulation, Lipoprotein Oxidation, and Macrophage Lipid Uptake in Hypercholesterolemic Zebrafish

    Konstantin Stoletov;Longhou Fang;Soo Ho Choi;Karsten Hartvigsen

  • Catch of the day : zebrafish as a human cancer model

    K Stoletov;R Klemke

  • ErbB2 Is Necessary for Induction of Carcinoma Cell Invasion by Erbb Family Receptor Tyrosine Kinases

    Kathryn S.R. Spencer;Diana Graus-Porta;Jie Leng;Nancy E. Hynes

  • Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold

    Samuel Y. Cho;Richard L. Klemke

  • Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold.

    David Chodniewicz;Richard L Klemke

  • Insulin-like growth factor receptor cooperates with integrin alpha v beta 5 to promote tumor cell dissemination in vivo.

    P C Brooks;R L Klemke;S Schon;J M Lewis

Frequent Co-Authors

David A. Cheresh
David A. Cheresh University of California, San Diego
Michael Bouvet
Michael Bouvet University of California, San Diego
Robert M. Hoffman
Robert M. Hoffman AntiCancer (United States)
Wei Wang
Wei Wang University of California, San Diego
Richard D. Smith
Richard D. Smith Pacific Northwest National Laboratory
David G. Camp
David G. Camp Pacific Northwest National Laboratory
Steven L. Gonias
Steven L. Gonias University of California, San Diego
John R. Yates
John R. Yates Scripps Research Institute
Yury I. Miller
Yury I. Miller University of California, San Diego
Dwayne G. Stupack
Dwayne G. Stupack University of California, San Diego

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