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Chemistry

D-Index
102
Citations
32499
World Ranking
1189
National Ranking
465

Research.com Recognitions

  • 2019 - Murray Goodman Memorial Prize, American Chemical Society (ACS)
  • 2001 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1994 - Fellow of Alfred P. Sloan Foundation

Overview

Eric T. Kool is affiliated with Stanford University in the United States and specializes in the field of Biochemistry, Genetics, and Molecular Biology, with a strong emphasis on Molecular Biology. Their research spans across subfields including Organic Chemistry, Oncology, Cancer Research, and Clinical Biochemistry.

The main topics of their work encompass RNA and protein synthesis mechanisms, RNA modifications and cancer, DNA and nucleic acid chemistry, DNA repair mechanisms, advanced biosensing and bioanalysis techniques, RNA research and splicing, as well as chemical synthesis and analysis.

Frequent publication venues for their research include bioRxiv (Cold Spring Harbor Laboratory), Angewandte Chemie International Edition, Angewandte Chemie, Cancer Research, and the Journal of the American Chemical Society.

Recent papers authored by or associated with Eric T. Kool cover diverse topics and are published in prominent scientific journals:

  • Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries, 2021, Nature Biotechnology
  • Reversible 2'-OH acylation enhances RNA stability, 2023, Nature Chemistry
  • Site-Selective RNA Functionalization via DNA-Induced Structure, 2020, Journal of the American Chemical Society
  • Pervasive transcriptome interactions of protein-targeted drugs, 2023, Nature Chemistry
  • Small-Molecule Inhibitor of 8-Oxoguanine DNA Glycosylase 1 Regulates Inflammatory Responses during Pseudomonas aeruginosa Infection, 2020, The Journal of Immunology

Frequent co-authors contributing to their body of work include Lu Xiao, Yong Woong Jun, David L. Wilson, Linglan Fang, and Michael G. Mohsen.

Eric T. Kool's scientific contributions have been recognized through various awards such as the Murray Goodman Memorial Prize from the American Chemical Society in 2019, Fellowship of the American Association for the Advancement of Science in 2001, and Fellowship of the Alfred P. Sloan Foundation in 1994.

Best Publications

  • Structural imprints in vivo decode RNA regulatory mechanisms

    Robert C. Spitale;Ryan A. Flynn;Qiangfeng Cliff Zhang;Pete Crisalli

  • Hydrogen bonding, base stacking, and steric effects in dna replication.

    Eric T. Kool

  • Oximes and Hydrazones in Bioconjugation: Mechanism and Catalysis

    Dominik K. Kölmel;Eric T. Kool

  • Factors Contributing to Aromatic Stacking in Water: Evaluation in the Context of DNA

    Kevin M. Guckian;Barbara A. Schweitzer;Rex X.-F. Ren;Charles J. Sheils

  • Rolling Circle DNA Synthesis: Small Circular Oligonucleotides as Efficient Templates for DNA Polymerases

    Dongyu Liu;Sarah L. Daubendiek;Martin A. Zillman;Kevin Ryan

  • Replacing the nucleobases in DNA with designer molecules.

    Eric T. Kool

  • RNA SHAPE analysis in living cells

    Robert C Spitale;Pete Crisalli;Ryan A Flynn;Eduardo A Torre

  • Mimicking the Structure and Function of DNA: Insights into DNA Stability and Replication

    Eric T. Kool;Juan C. Morales;Kevin M. Guckian

  • Active site tightness and substrate fit in DNA replication.

    Eric T. Kool

  • Escherichia coli RNA Polymerase Activity Observed Using Atomic Force Microscopy

    Sandor Kasas;Neil H. Thomson;Bettye L. Smith;Helen G. Hansma

  • A thymidine triphosphate shape analog lacking Watson–Crick pairing ability is replicated with high sequence selectivity

    Sean Moran;Rex X.-F. Ren;Eric T. Kool

  • Structure and thermodynamics of N6-methyladenosine in RNA: a spring-loaded base modification

    Caroline Roost;Stephen R. Lynch;Pedro J. Batista;Kun Qu

  • Preorganization of DNA: Design Principles for Improving Nucleic Acid Recognition by Synthetic Oligonucleotides

    Eric T. Kool

  • Difluorotoluene, a Nonpolar Isostere for Thymine, Codes Specifically and Efficiently for Adenine in DNA Replication.

    Sean Moran;Rex X.-F. Ren;Squire Rumney;Eric T. Kool

  • Efficient replication between non-hydrogen-bonded nucleoside shape analogs

    Juan C. Morales;Eric T. Kool

  • The Discovery of Rolling Circle Amplification and Rolling Circle Transcription.

    Michael G. Mohsen;Eric T. Kool

  • DNA-Multichromophore Systems

    Yin Nah Teo;Eric T. Kool

  • HYDROPHOBIC, NON-HYDROGEN-BONDING BASES AND BASE PAIRS IN DNA

    Barbara A. Schweitzer;Eric T. Kool

  • Experimental Measurement of Aromatic Stacking Affinities in the Context of Duplex DNA

    Kevin M. Guckian;Barbara A. Schweitzer;Rex X.-F. Ren;Charles J. Sheils

  • A specific partner for abasic damage in DNA

    Tracy J. Matray;Eric T. Kool

  • Rolling circle synthesis of oligonucleotides and amplification of select randomized circular oligonucleotides

    Eric T. Kool

Frequent Co-Authors

Howard Y. Chang
Howard Y. Chang Amgen (United States)
Sheila S. David
Sheila S. David University of California, Davis
Hiroshi Abe
Hiroshi Abe Nagoya University
Herman O. Sintim
Herman O. Sintim Purdue University West Lafayette
Dong Wang
Dong Wang Peking University
Thomas A. Kunkel
Thomas A. Kunkel National Institutes of Health
Philipp Holliger
Philipp Holliger MRC Laboratory of Molecular Biology
Mikhail Kashlev
Mikhail Kashlev National Institutes of Health
Paul K. Hansma
Paul K. Hansma University of California, Santa Barbara

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