2019 - Murray Goodman Memorial Prize, American Chemical Society (ACS)
2001 - Fellow of the American Association for the Advancement of Science (AAAS)
1994 - Fellow of Alfred P. Sloan Foundation
His main research concerns DNA, Stereochemistry, RNA, Base pair and Oligonucleotide. His DNA study is focused on Biochemistry in general. His research in Stereochemistry intersects with topics in Thymine, Helix, Nucleobase and Stacking.
Eric T. Kool combines subjects such as Förster resonance energy transfer, Polymerase and Escherichia coli with his study of RNA. The Base pair study combines topics in areas such as Steric effects, DNA polymerase I, Hydrogen bond, DNA polymerase and DNA replication. The study incorporates disciplines such as Ribosomal RNA, Molecular recognition, Biophysics, Molecular biology and Rolling circle replication in addition to Oligonucleotide.
His scientific interests lie mostly in DNA, Biochemistry, Stereochemistry, Base pair and Oligonucleotide. His DNA research incorporates themes from RNA, Combinatorial chemistry, Nucleic acid and Nucleotide. His research integrates issues of Molecule and Organic chemistry in his study of Combinatorial chemistry.
His Stereochemistry research is multidisciplinary, relying on both Thymine, Stacking, xDNA and Thymidine. His Base pair research is multidisciplinary, incorporating perspectives in Steric effects, DNA polymerase I, Hydrogen bond, DNA polymerase and DNA replication. His work in Oligonucleotide addresses subjects such as Molecular biology, which are connected to disciplines such as Rolling circle replication.
His primary areas of study are DNA, Biochemistry, RNA, Enzyme and DNA repair. His DNA study integrates concerns from other disciplines, such as Environmental chemistry and Transcription. Biochemistry and Hydrazone are frequently intertwined in his study.
His RNA study combines topics from a wide range of disciplines, such as Nucleic acid, Surface modification and Acylation. His Nucleic acid research is multidisciplinary, incorporating elements of Azide, Nucleobase, Stereochemistry and Function. His study looks at the relationship between Polymerase and topics such as DNA polymerase, which overlap with DNA clamp.
His primary scientific interests are in RNA, Biochemistry, DNA, Computational biology and Enzyme. His studies deal with areas such as Nucleobase, Nucleic acid and Acylation as well as RNA. Eric T. Kool interconnects DNA clamp and Primer in the investigation of issues within DNA.
His Computational biology research integrates issues from Genetics, Transcription and Molecular biology. His work in Aptamer covers topics such as Azide which are related to areas like Stereochemistry. His work deals with themes such as RNA Stability, Base pair, Stem-loop, RNA splicing and Methyl group, which intersect with Stereochemistry.
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Hydrogen bonding, base stacking, and steric effects in dna replication.
Eric T. Kool.
Annual Review of Biophysics and Biomolecular Structure (2001)
Factors Contributing to Aromatic Stacking in Water: Evaluation in the Context of DNA
Kevin M. Guckian;Barbara A. Schweitzer;Rex X.-F. Ren;Charles J. Sheils.
Journal of the American Chemical Society (2000)
Structural imprints in vivo decode RNA regulatory mechanisms
Robert C. Spitale;Ryan A. Flynn;Qiangfeng Cliff Zhang;Pete Crisalli.
Nature (2015)
Rolling Circle DNA Synthesis: Small Circular Oligonucleotides as Efficient Templates for DNA Polymerases
Dongyu Liu;Sarah L. Daubendiek;Martin A. Zillman;Kevin Ryan.
Journal of the American Chemical Society (1996)
Replacing the nucleobases in DNA with designer molecules.
Eric T. Kool.
Accounts of Chemical Research (2002)
Mimicking the Structure and Function of DNA: Insights into DNA Stability and Replication
Eric T. Kool;Juan C. Morales;Kevin M. Guckian.
Angewandte Chemie (2000)
Active site tightness and substrate fit in DNA replication.
Eric T. Kool.
Annual Review of Biochemistry (2002)
Escherichia coli RNA Polymerase Activity Observed Using Atomic Force Microscopy
Sandor Kasas;Neil H. Thomson;Bettye L. Smith;Helen G. Hansma.
Biochemistry (1997)
A thymidine triphosphate shape analog lacking Watson–Crick pairing ability is replicated with high sequence selectivity
Sean Moran;Rex X.-F. Ren;Eric T. Kool.
Proceedings of the National Academy of Sciences of the United States of America (1997)
Oximes and Hydrazones in Bioconjugation: Mechanism and Catalysis
Dominik K. Kölmel;Eric T. Kool.
Chemical Reviews (2017)
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