Roland J. Siezen mostly deals with Biochemistry, Genetics, Genome, Peptide sequence and Lactococcus lactis. His Biochemistry research is multidisciplinary, incorporating elements of Lantibiotics, Biophysics and Bacteria. As part of his studies on Genetics, Roland J. Siezen often connects relevant areas like Mycobacterium tuberculosis.
His Genome research integrates issues from Lactobacillus plantarum, In silico and Computational biology. His studies in Peptide sequence integrate themes in fields like Protein structure, Molecular biology, Subtilisin and Mutant. His Lactococcus lactis research is multidisciplinary, incorporating perspectives in Plasmid, Restriction map, Replicon, Permease and Horizontal gene transfer.
His primary areas of investigation include Genetics, Biochemistry, Genome, Gene and Lactococcus lactis. His Genetics study frequently intersects with other fields, such as Mycobacterium tuberculosis. His Biochemistry research is multidisciplinary, relying on both Nisin, Lantibiotics and Bacteria.
Roland J. Siezen has included themes like Lactobacillus plantarum, Computational biology and Microbiology in his Genome study. His study in the field of Niche adaptation, Conserved sequence, Phenotype and In silico also crosses realms of Prophage. His Lactococcus lactis study combines topics in areas such as Molecular biology and Signal peptide.
Roland J. Siezen focuses on Genetics, Genome, Computational biology, Microbiology and Gene. As part of his studies on Genetics, he often connects relevant subjects like Mycobacterium tuberculosis. He has included themes like Plasmid, DNA microarray and Bacteria in his Genome study.
His Computational biology research is multidisciplinary, incorporating perspectives in RefSeq and Metagenomics. Roland J. Siezen has researched Microbiology in several fields, including Fermentation, Biochemistry, Gluten, Subtilisins and Lactic acid bacterium. The various areas that Roland J. Siezen examines in his Biochemistry study include Cereus, Bacillus cereus and Microbial metabolism.
Roland J. Siezen spends much of his time researching Genome, Genetics, Gene, Comparative genomics and Computational biology. His Genome research includes elements of Plasmid and Lactobacillus plantarum. His work on DNA microarray and Multiple sequence alignment is typically connected to Support vector machine, Cluster analysis and Markov chain as part of general Genetics study, connecting several disciplines of science.
In general Gene, his work in Niche adaptation and Virulence is often linked to Human health linking many areas of study. Roland J. Siezen usually deals with Comparative genomics and limits it to topics linked to Phenotype and Strain and Proteomics. His Computational biology research incorporates elements of Protein domain, Sequence analysis and Sequence alignment.
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Complete genome sequence of Lactobacillus plantarum WCFS1
Michiel Kleerebezem;Jos Boekhorst;Richard van Kranenburg;Douwe Molenaar.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Subtilases: the superfamily of subtilisin-like serine proteases.
Roland J. Siezen;Jack A. M. Leunissen.
Protein Science (1997)
Characterization of the nisin gene cluster nisABTCIPR of Lactococcus lactis. Requirement of expression of the nisA and nisI genes for development of immunity
Oscar P. Kuipers;Marke M. Beerthuyzen;Roland J. Siezen;Willem M. De Vos.
FEBS Journal (1993)
Identification and characterization of the lantibiotic nisin Z, a natural nisin variant
John W. M. Mulders;Ingrid J. Boerrigter;Harry S. Rollema;Roland J. Siezen.
FEBS Journal (1991)
Homology modelling and protein engineering strategy of subtilases, the family of subtilisin-like serine proteinases
Roland J. Siezen;William M. de Vos;Jack A.M. Leunissen;Bauke W. Dijkstra.
Protein Engineering (1991)
Epochal Evolution of GGII.4 Norovirus Capsid Proteins from 1995 to 2006
J. Joukje Siebenga;J. Joukje Siebenga;Harry Vennema;Bernadet Renckens;Erwin de Bruin.
Journal of Virology (2007)
The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteria
Nico C Gey van Pittius;Junaid Gamieldien;Winston Hide;Gordon D Brown.
Genome Biology (2001)
The extracellular biology of the lactobacilli
Michiel Kleerebezem;Pascal Hols;Elvis Bernard;Thomas Rolain.
Fems Microbiology Reviews (2010)
Cloning of usp45, a gene encoding a secreted protein from Lactococcus lactis subsp. lactis MG1363.
M van Asseldonk;G Rutten;M Oteman;R J Siezen.
Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes
W. J. M. Van De Ven;J. Voorberg;R. Fontijn;H. Pannekoek.
Molecular Biology Reports (1990)
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