World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
109
Citations
45068
World Ranking
252
National Ranking
118

Research.com Recognitions

  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2004 - American Dairy Science Association Fellowship Award
  • 2001 - Member of the National Academy of Sciences
  • 1996 - Zinpro Award for Excellence in Dairy Science, American Dairy Science Association

Overview

Todd R. Klaenhammer was affiliated with North Carolina State University in the United States. Their research primarily focused on biochemistry, genetics, and molecular biology, with significant contributions to agricultural and biological sciences. The scientist's work involved several subfields including molecular biology, food science, genetics, nutrition and dietetics, and infectious diseases.

Klaenhammer's scholarly output included research on probiotics and fermented foods, gut microbiota and health, digestive system and related health, infant nutrition and health, viral gastroenteritis research and epidemiology, diet, metabolism and disease, and enzyme production and characterization.

They published extensively with frequent contributions to venues such as UNC Libraries, Gut Microbes, mBio, and Applied and Environmental Microbiology. Among their recent works were:

  • A double-blind, 377-subject randomized study identifies Ruminococcus, Coprococcus, Christensenella, and Collinsella as long-term potential key players in the modulation of the gut microbiome of lactose intolerant individuals by galacto-oligosaccharides, 2021, Gut Microbes
  • In Vivo Transcriptome of Lactobacillus acidophilus and Colonization Impact on Murine Host Intestinal Gene Expression, 2021, mBio
  • Impact of short-chain galactooligosaccharides on the gut microbiome of lactose-intolerant individuals, 2020, UNC Libraries
  • The S-layer Associated Serine Protease Homolog PrtX Impacts Cell Surface-Mediated Microbe-Host Interactions of Lactobacillus acidophilus NCFM, 2020, UNC Libraries
  • Characterization of the Fecal Microbiota Using High-Throughput Sequencing Reveals a Stable Microbial Community during Storage, 2020, UNC Libraries

Klaenhammer frequently collaborated with several coauthors, including:

  • M. Andrea Azcárate-Peril
  • Andrew J. Ritter
  • Dennis A. Savaiano
  • Yong Jun Goh
  • Rodolphe Barrangou

The scientist received a number of awards during their career. These included being named a Fellow of the American Association for the Advancement of Science in 2009, receiving the American Dairy Science Association Fellowship Award in 2004, becoming a member of the National Academy of Sciences in 2001, and the Zinpro Award for Excellence in Dairy Science from the American Dairy Science Association in 1996.

Best Publications

  • Genetics of bacteriocins produced by lactic acid bacteria

    Todd R. Klaenhammer

  • Bacteriocins of lactic acid bacteria

    Todd R. Klaenhammer

  • Comparative genomics of the lactic acid bacteria

    K. Makarova;A. Slesarev;Y. Wolf;A. Sorokin

  • Detection and activity of lactacin B, a bacteriocin produced by Lactobacillus acidophilus.

    S F Barefoot;T R Klaenhammer

  • A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes

    Richard J. Roberts;Marlene Belfort;Timothy Bestor;Ashok S. Bhagwat

  • Nisin treatment for inactivation of Salmonella species and other gram-negative bacteria.

    K A Stevens;B W Sheldon;N A Klapes;T R Klaenhammer

  • Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM

    Eric Altermann;W. Michael Russell;M. Andrea Azcarate-Peril;Rodolphe Barrangou

  • New scientific paradigms for probiotics and prebiotics.

    Gregor Reid;M E Sanders;H Rex Gaskins;Glenn R Gibson

  • S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions

    Sergey R. Konstantinov;Hauke Smidt;Willem M. de Vos;Willem M. de Vos;Sven C. M. Bruijns

  • The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533

    R. David Pridmore;Bernard Berger;Frank Desiere;David Vilanova

  • Invited review: the scientific basis of Lactobacillus acidophilus NCFM functionality as a probiotic.

    M.E. Sanders;T.R. Klaenhammer

  • Lactobacilli activate human dendritic cells that skew T cells toward T helper 1 polarization

    Mansour Mohamadzadeh;Scott Olson;Warren V. Kalina;Gordon Ruthel

  • Characterization and purification of helveticin J and evidence for a chromosomally determined bacteriocin produced by Lactobacillus helveticus 481.

    M C Joerger;T R Klaenhammer

  • Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera

    Zhihong Sun;Hugh M B Harris;Angela McCann;Chenyi Guo

  • Genome-scale analyses of health-promoting bacteria: probiogenomics.

    Marco Ventura;Sarah Josephine O'Flaherty;Marcus J. Claesson;Francesca Turroni

  • Functional Analysis of Putative Adhesion Factors in Lactobacillus acidophilus NCFM

    B. Logan Buck;Eric Altermann;Tina Svingerud;Todd R. Klaenhammer

  • Rapid Mini-Prep Isolation of High-Quality Plasmid DNA from Lactococcus and Lactobacillus spp.

    Daniel J. O'Sullivan;Todd R. Klaenhammer

  • Selection and design of probiotics.

    Todd R Klaenhammer;Martin J Kullen

  • Antimicrobial activity of lactic acid bacteria against Listeria monocytogenes

    L. J. Harris;M. A. Daeschel;M. E. Stiles;T. R. Klaenhammer

  • PathwayVoyager: pathway mapping using the Kyoto Encyclopedia of Genes and Genomes (KEGG) database

    Eric Altermann;Todd R Klaenhammer

  • A nomenclature for restriction enzymes, DNA methyl transferases, homing endonucleases and their genes

    RJ Roberts;M Belford;T Bester;AS Bhagwat

Frequent Co-Authors

Eric Altermann
Eric Altermann Massey University
Rodolphe Barrangou
Rodolphe Barrangou North Carolina State University
Colin Hill
Colin Hill University College Cork
Birte Svensson
Birte Svensson Technical University of Denmark
Henry P. Fleming
Henry P. Fleming North Carolina State University
Mansour Mohamadzadeh
Mansour Mohamadzadeh The University of Texas Health Science Center at San Antonio
Sylvain Moineau
Sylvain Moineau Université Laval
Glenn R. Gibson
Glenn R. Gibson University of Reading
Willem M. de Vos
Willem M. de Vos Wageningen University & Research
Linda J. Harris
Linda J. Harris University of California, Davis

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