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Microbiology

D-Index
64
Citations
15553
World Ranking
2601
National Ranking
1048

Overview

Harlan D. Caldwell is primarily affiliated with the National Institute of Allergy and Infectious Diseases in the United States. Their research contributions focus largely on infectious diseases, immunology, and microbiology, with a strong emphasis on reproductive tract infections and associated immune responses.

The scientist's main fields of study include Immunology and Microbiology, and Medicine. Their work spans various subfields such as Microbiology, Immunology, Epidemiology, Surgery, and Molecular Biology.

Key topics addressed in their research include:

  • Reproductive tract infections research
  • Reproductive System and Pregnancy
  • Inflammasome and immune disorders
  • Eosinophilic Esophagitis
  • Cervical Cancer and HPV Research
  • Clostridium difficile and Clostridium perfringens research
  • Hepatitis B Virus Studies

Harlan D. Caldwell has published several recent papers across notable journals in infectious disease and immunology. Selected publications include:

  • "Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor," 2021, Nature Communications
  • "Chlamydia trachomatis Plasmid Gene Protein 3 Is Essential for the Establishment of Persistent Infection and Associated Immunopathology," 2020, mBio
  • "A Chlamydial Plasmid-Dependent Secretion System for the Delivery of Virulence Factors to the Host Cytosol," 2021, mBio
  • "TargeTron Inactivation of Chlamydia trachomatis gseA Results in a Lipopolysaccharide 3-Deoxy- d -Manno-Oct-2-Ulosonic Acid-Deficient Strain That Is Cytotoxic for Cells," 2023, Infection and Immunity
  • "TargeTron inactivation of plasmid-regulated Chlamydia trachomatis CT084 results in a nonlytic phenotype," 2023, Pathogens and Disease

Their research is distributed in prominent scientific venues, especially in mBio with two publications, along with Nature Communications, Infection and Immunity, and Pathogens and Disease.

Frequent co-authors collaborating with Harlan D. Caldwell include:

  • Chunfu Yang
  • Grant McClarty
  • Lei Lei
  • Li Ma
  • Craig Martens

Best Publications

  • Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis

    Unknown

  • Genomic transcriptional profiling of the developmental cycle of Chlamydia trachomatis.

    Robert J. Belland;Guangming Zhong;Deborah D. Crane;Daniel Hogan

  • Immunity to Murine Chlamydial Genital Infection

    Richard P. Morrison;Harlan D. Caldwell

  • Chlamydial disease pathogenesis. The 57-kD chlamydial hypersensitivity antigen is a stress response protein.

    R P Morrison;R J Belland;K Lyng;H D Caldwell

  • Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-gamma-dependent and -independent pathways.

    Unknown

  • Mapping antigenic domains expressed by Chlamydia trachomatis major outer membrane protein genes.

    Wolfgang Baehr;You-Xun Zhang;Theresa Joseph;Hua Su

  • Polymorphisms in Chlamydia trachomatis tryptophan synthase genes differentiate between genital and ocular isolates

    Harlan D. Caldwell;Heidi Wood;Debbie Crane;Robin Bailey

  • Nucleotide and deduced amino acid sequences for the four variable domains of the major outer membrane proteins of the 15 Chlamydia trachomatis serovars.

    Ying Yuan;You-Xun Zhang;N. G. Watkins;H. D. Caldwell

  • CD4+ T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract.

    Hua Su;H. D. Caldwell

  • Immunity to murine Chlamydia trachomatis genital tract reinfection involves B cells and CD4(+) T cells but not CD8(+) T cells.

    Sandra G. Morrison;Hua Su;Harlan D. Caldwell;Richard P. Morrison

  • Transcriptome analysis of chlamydial growth during IFN-γ-mediated persistence and reactivation

    Robert J. Belland;David E. Nelson;Dezso Virok;Deborah D. Crane

  • Comparative Genomic Analysis of Chlamydia trachomatis Oculotropic and Genitotropic Strains

    John H. Carlson;Stephen F. Porcella;Grant McClarty;Harlan D. Caldwell

  • Chlamydial disease pathogenesis. Ocular hypersensitivity elicited by a genus-specific 57-kD protein.

    R P Morrison;K Lyng;H D Caldwell

  • Vaccination against Chlamydial Genital Tract Infection after Immunization with Dendritic Cells Pulsed Ex Vivo with Nonviable Chlamydiae

    Hua Su;Ronald Messer;William Whitmire;Elizabeth Fischer

  • Chlamydia trachomatis-host cell interactions: role of the chlamydial major outer membrane protein as an adhesin.

    Hua Su;N. G. Watkins;You-Xun Zhang;H. D. Caldwell

  • Chlamydia trachomatis genital tract infection of antibody-deficient gene knockout mice.

    H Su;K Feilzer;H D Caldwell;R P Morrison

  • Chlamydia trachomatis cytotoxicity associated with complete and partial cytotoxin genes

    Robert J. Belland;Marci A. Scidmore;Deborah D. Crane;Daniel M. Hogan

  • Protective efficacy of major outer membrane protein-specific immunoglobulin A (IgA) and IgG monoclonal antibodies in a murine model of Chlamydia trachomatis genital tract infection.

    T. W. Cotter;Qing Meng;Ze-Li Shen;You-Xun Zhang

  • Chlamydial IFN-γ immune evasion is linked to host infection tropism

    Unknown

  • A recombinant Chlamydia trachomatis major outer membrane protein binds to heparan sulfate receptors on epithelial cells

    Hua Su;Lynne Raymond;Daniel D. Rockey;Elizabeth Fischer

  • The Chlamydia trachomatis Plasmid Is a Transcriptional Regulator of Chromosomal Genes and a Virulence Factor

    John H. Carlson;William M. Whitmire;Deborah D. Crane;Luke Wicke

  • Antigenic analysis of the major outer membrane protein of Chlamydia spp.

    Harlan D. Caldwell;Julius Schachter

  • Chlamydia trachomatis polymorphic membrane protein D is a species-common pan-neutralizing antigen

    Deborah D. Crane;John H. Carlson;Elizabeth R. Fischer;Patrik Bavoil

  • Chlamydia trachomatis plasmid-encoded Pgp4 is a transcriptional regulator of virulence-associated genes.

    Lihua Song;John H. Carlson;William M. Whitmire;Laszlo Kari

Frequent Co-Authors

Cho-Chou Kuo
Cho-Chou Kuo University of Washington
George E. Kenny
George E. Kenny University of Washington
Elizabeth R. Fischer
Elizabeth R. Fischer National Institutes of Health
Daniel E. Sturdevant
Daniel E. Sturdevant National Institutes of Health
Stephen F. Porcella
Stephen F. Porcella National Institutes of Health
Julius Schachter
Julius Schachter University of California, San Francisco
Robin L. Bailey
Robin L. Bailey London School of Hygiene & Tropical Medicine
Gerald I. Byrne
Gerald I. Byrne University of Tennessee Health Science Center
Walter E. Stamm
Walter E. Stamm University of Washington
Sheila K. West
Sheila K. West University of Pennsylvania

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