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Microbiology

D-Index
63
Citations
12739
World Ranking
2768
National Ranking
246

Overview

Ian N. Clarke is affiliated with the University of Southampton in the United Kingdom. Their research primarily focuses on topics within Medicine, Immunology and Microbiology, and Health Professions, with notable contributions in the subfields of Microbiology, General Health Professions, Ecology, Physiology, and Epidemiology.

The scientist has published extensively on topics related to reproductive tract infections research, bacteriophages and microbial interactions, syphilis diagnosis and treatment, urinary tract infections management, mental health and patient involvement, transgenic plants and applications, and the epidemiology of HIV, TB, and STIs.

Recent papers authored by Ian N. Clarke include the following:

  • An inducible transposon mutagenesis approach for the intracellular human pathogen Chlamydia trachomatis (2021, Wellcome Open Research)
  • The Nature and Extent of Plasmid Variation in Chlamydia trachomatis (2020, Microorganisms)
  • Diversity in Chlamydial plasmids (2020, PLoS ONE)
  • High-resolution genotyping of Lymphogranuloma Venereum (LGV) strains of Chlamydia trachomatis in London using multi-locus VNTR analysis-ompA genotyping (MLVA-ompA) (2021, PLoS ONE)
  • Progress towards an inducible, replication-proficient transposon delivery vector for Chlamydia trachomatis (2021, Wellcome Open Research)

Their frequent coauthors include:

  • Colette O'Neill
  • Nicholas R. Thomson
  • Rachel J. Skilton
  • David Cleary
  • David J. Lampe

Ian N. Clarke's work appears regularly in several publication venues, including:

  • Wellcome Open Research
  • PLoS ONE
  • Microorganisms
  • Viruses
  • Pathogens and Disease

The scope of Ian N. Clarke's research covers infectious disease mechanisms, microbial genetics, and the epidemiology of bacterial pathogens, with a particular emphasis on Chlamydia trachomatis. The integration of molecular approaches, such as transposon mutagenesis and plasmid variability studies, is a core aspect of their scientific contributions.

Best Publications

  • Norwalk-like viruses

    Ian N. Clarke;Paul R. Lambden

  • Taxonomy of the caliciviruses.

    K Y Green;T Ando;M S Balayan;T Berke

  • Development of a transformation system for Chlamydia trachomatis: restoration of glycogen biosynthesis by acquisition of a plasmid shuttle vector.

    Yibing Wang;Simona Kahane;Lesley T. Cutcliffe;Rachel J. Skilton

  • Sequence and genome organization of a human small round-structured (Norwalk-like) virus.

    PR Lambden;EO Caul;CR Ashley;IN Clarke

  • Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing

    Simon R Harris;Ian N Clarke;Helena M B Seth-Smith;Anthony W Solomon

  • Chlamydia trachomatis: Genome sequence analysis of lymphogranuloma venereum isolates

    Nicholas R. Thomson;Matthew T.G. Holden;Caroline Carder;Nicola Lennard

  • Genotypic and Physiological Characterization of Saccharomyces boulardii, the Probiotic Strain of Saccharomyces cerevisiae

    Laura Edwards-Ingram;Paul Gitsham;Nicola Burton;Geoff Warhurst

  • Cloning of noncultivatable human rotavirus by single primer amplification.

    P R Lambden;S J Cooke;E O Caul;I N Clarke

  • Point mutation in meningococcal por A gene associated with increased endemic disease.

    B.T. McGuinness;I.N. Clarke;P.R. Lambden;A.K. Barlow

  • Molecular Characterization of a Bovine Enteric Calicivirus: Relationship to the Norwalk-Like Viruses

    B. L. Liu;P. R. Lambden;H. Günther;P. Otto

  • Organization and Expression of Calicivirus Genes

    Ian N. Clarke;Paul R. Lambden

  • The molecular biology of caliciviruses.

    Ian N. Clarke;Paul R. Lambden

  • Human enteric Caliciviridae: the complete genome sequence and expression of virus-like particles from a genetic group II small round structured virus

    Dingle Ke;Lambden Pr;Caul Eo;Clarke In

  • Management of hospital outbreaks of gastro-enteritis due to small roundstructured viruses.

    P. R. Chadwick;G. Beards;D. Brown;E. O. Caul

  • Deduced amino acid sequences of class 1 protein (PorA) from three strains of Neisseria meningitidis. Synthetic peptides define the epitopes responsible for serosubtype specificity.

    Brian McGuinness;Ann K. Barlow;Ian N. Clarke;John E. Farley

  • Human enteric caliciviruses have a unique genome structure and are distinct from the Norwalk-like viruses

    B. L. Liu;I. N. Clarke;E. O. Caul;P. R. Lambden

  • Cloning and nucleotide sequencing of the Clostridium perfringens epsilon-toxin gene and its expression in Escherichia coli.

    S. E. C. Hunter;I. N. Clarke;D. C. Kelly;R. W. Titball

  • The plasmids of Chlamydia trachomatis and Chlamydophila pneumoniae (N16): accurate determination of copy number and the paradoxical effect of plasmid-curing agents

    Mark A. Pickett;J. Sylvia Everson;Patrick J. Pead;Ian N. Clarke

  • Polyprotein processing in Southampton virus: identification of 3C-like protease cleavage sites by in vitro mutagenesis.

    Binlei Liu;I. N. Clarke;P. R. Lambden

  • Plasmid diversity in Chlamydia

    NS Thomas;ME Lusher;CC Storey;IN Clarke

Frequent Co-Authors

Paul R. Lambden
Paul R. Lambden Southampton General Hospital
Nicholas R. Thomson
Nicholas R. Thomson Wellcome Sanger Institute
John E. Heckels
John E. Heckels University of Southampton
Simon R. Harris
Simon R. Harris Wellcome Sanger Institute
Martin J. Holland
Martin J. Holland London School of Hygiene & Tropical Medicine
Magnus Unemo
Magnus Unemo Örebro University
David Mabey
David Mabey London School of Hygiene & Tropical Medicine
Julian Parkhill
Julian Parkhill University of Cambridge
Robin L. Bailey
Robin L. Bailey London School of Hygiene & Tropical Medicine
Taane G. Clark
Taane G. Clark London School of Hygiene & Tropical Medicine

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