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Immunology

D-Index
58
Citations
10010
World Ranking
3557
National Ranking
307

Overview

Martin J. Holland is affiliated with the London School of Hygiene & Tropical Medicine in the United Kingdom. Their research spans several interconnected fields primarily focused on medicine, immunology, and microbiology, with notable contributions to subfields such as microbiology, epidemiology, molecular biology, immunology, and physiology.

Their work addresses multiple topics within reproductive tract infections research, gut microbiota and health, syphilis diagnosis and treatment, cervical cancer and HPV research, urinary tract infections management, immune response and inflammation, as well as ocular surface and contact lens studies.

Recent publications by Martin J. Holland include the following:

  • Impact of azithromycin mass drug administration on the antibiotic-resistant gut microbiome in children: a randomized, controlled trial (2022, Gut Pathogens)
  • A Chlamydia trachomatis VD1-MOMP vaccine elicits cross-neutralizing and protective antibodies against C/C-related complex serovars (2021, npj Vaccines)
  • The influence of groundwater abstraction on interpreting climate controls and extreme recharge events from well hydrographs in semi-arid South Africa (2021, Hydrogeology Journal)
  • Viability PCR shows that non-ocular surfaces could contribute to transmission of Chlamydia trachomatis infection in trachoma (2020, PLoS neglected tropical diseases)
  • When Bacteria and Viruses Collide: A Tale of Chlamydia trachomatis and Sexually Transmitted Viruses (2023, Viruses)

Frequent coauthors collaborating with Martin J. Holland include:

  • Harry Pickering
  • Robin L. Bailey
  • David Mabey
  • Matthew J. Burton
  • Tamsyn Derrick

Their research outputs have been published repeatedly in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)
  • PLoS neglected tropical diseases
  • npj Vaccines
  • UNC Libraries

Best Publications

  • Biogeography of the ecosystems of the healthy human body

    Yanjiao Zhou;Hongyu Gao;Kathie A Mihindukulasuriya;Patricio S La Rosa

  • Revealing the history of sheep domestication using retrovirus integrations

    Bernardo Chessa;Filipe Pereira;Frederick Arnaud;Antonio Amorim

  • Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing

    Simon R Harris;Ian N Clarke;Helena M B Seth-Smith;Anthony W Solomon

  • Strategies for control of trachoma: observational study with quantitative PCR.

    Anthony W Solomon;Anthony W Solomon;Martin J Holland;Martin J Holland;Matthew J Burton;Matthew J Burton;Sheila K West

  • Mass Treatment with Single-Dose Azithromycin for Trachoma

    Anthony W. Solomon;Martin J. Holland;Martin J. Holland;Neal D.E. Alexander;Patrick A. Massae

  • Scarring trachoma is associated with polymorphism in the tumor necrosis factor alpha (TNF-alpha) gene promoter and with elevated TNF-alpha levels in tear fluid.

    D. J. Conway;M. J. Holland;R. L. Bailey;A. E. Campbell

  • Selective maturation of dendritic cells by Nippostrongylus brasiliensis-secreted proteins drives Th2 immune responses

    Adam Balic;Yvonne Harcus;Martin J Holland;Martin J Holland;Rick M Maizels

  • T helper type-1 (Th1)/Th2 profiles of peripheral blood mononuclear cells (PBMC); responses to antigens of Chlamydia trachomatis in subjects with severe trachomatous scarring.

    M J Holland;R L Bailey;D J Conway;F Culley

  • The conjunctival microbiome in health and trachomatous disease: a case control study.

    Yanjiao Zhou;Yanjiao Zhou;Martin J Holland;Pateh Makalo;Hassan Joof

  • Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses.

    Martin J. Holland;Yvonne M. Harcus;Philip L. Riches;Rick M. Maizels

  • Which members of a community need antibiotics to control trachoma? Conjunctival Chlamydia trachomatis infection load in Gambian villages.

    Matthew J. Burton;Martin J. Holland;Martin J. Holland;Nkoyo Faal;Esther A. N. Aryee

  • Re-emergence of Chlamydia trachomatis infection after mass antibiotic treatment of a trachoma-endemic Gambian community: a longitudinal study

    Matthew J. Burton;Matthew J. Burton;Martin J. Holland;Martin J. Holland;Pateh Makalo;Esther A. N. Aryee

  • Co-evolution of genomes and plasmids within Chlamydia trachomatis and the emergence in Sweden of a new variant strain.

    Helena Mb Seth-Smith;Simon R. Harris;Kenneth M. Persson;Pete Marsh

  • Conjunctival scarring in trachoma is associated with depressed cell-mediated immune responses to chlamydial antigens.

    Martin J. Holland;Robin L. Bailey;Lyn J. Hayes;Hilton C. Whittle

  • Trachoma: Protective and Pathogenic Ocular Immune Responses to Chlamydia trachomatis

    Victor H. Hu;Martin J. Holland;Matthew J. Burton

  • Infection with Chlamydia trachomatis after mass treatment of a trachoma hyperendemic community in Tanzania: a longitudinal study

    S.K. West;B. Munoz;H. Mkocha;M.J. Holland

  • Development and Evaluation of a Next-Generation Digital PCR Diagnostic Assay for Ocular Chlamydia trachomatis Infections

    Chrissy h. Roberts;Sandra Molina-Gonzalez;Eunice Cassama

  • Jaagsiekte retrovirus establishes a disseminated infection of the lymphoid tissues of sheep affected by pulmonary adenomatosis

    Massimo Palmarini;Martin J. Holland;Christina Cousens;Robert G. Dalziel

  • A diagnostics platform for the integrated mapping, monitoring, and surveillance of neglected tropical diseases: rationale and target product profiles.

    Anthony W. Solomon;Dirk Engels;Robin L Bailey;Isobel M. Blake

  • Pathogenic Diversity among Chlamydia trachomatis Ocular Strains in Nonhuman Primates Is Affected by Subtle Genomic Variations

    Laszlo Kari;William M. Whitmire;John H. Carlson;Deborah D. Crane

  • Subjects recovering from human ocular chlamydial infection have enhanced lymphoproliferative responses to chlamydial antigens compared with those of persistently diseased controls.

    R. L. Bailey;M. J. Holland;H. C. Whittle;D. C. W. Mabey

  • Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians.

    Angels Natividad;Angels Natividad;Jeremy Hull;Gaia Luoni;Martin Holland;Martin Holland

Frequent Co-Authors

Robin L. Bailey
Robin L. Bailey London School of Hygiene & Tropical Medicine
David Mabey
David Mabey London School of Hygiene & Tropical Medicine
Sheila K. West
Sheila K. West University of Pennsylvania
John Hart
John Hart University of Illinois at Urbana-Champaign
Nicholas R. Thomson
Nicholas R. Thomson Wellcome Sanger Institute
Allen Foster
Allen Foster London School of Hygiene & Tropical Medicine
Dominic P. Kwiatkowski
Dominic P. Kwiatkowski University of Oxford
Rosanna W. Peeling
Rosanna W. Peeling London School of Hygiene & Tropical Medicine
Helen A. Weiss
Helen A. Weiss London School of Hygiene & Tropical Medicine
Ian N. Clarke
Ian N. Clarke University of Southampton

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