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Overview

Guangming Zhong is a researcher affiliated with The University of Texas Health Science Center at San Antonio in the United States. Their scholarly work predominantly engages with the fields of immunology and microbiology, with a significant volume of publications also intersecting with medicine.

The main domains of Zhong's research include microbiology, immunology, and epidemiology, complemented by studies in molecular biology and surgery. Their work covers key topics such as reproductive tract infections research, the reproductive system and pregnancy, cervical cancer and HPV research, urinary tract infections management, adolescent sexual and reproductive health, IL-33, ST2, and ILC pathways, and gut microbiota and health.

Zhong has authored numerous papers, contributing to a range of scientific venues. Notable recent publications include:

  • Chlamydia overcomes multiple gastrointestinal barriers to achieve long-lasting colonization, 2021, Trends in Microbiology
  • Adoptive Transfer of Group 3-Like Innate Lymphoid Cells Restores Mouse Colon Resistance to Colonization of a Gamma Interferon-Susceptible Chlamydia muridarum Mutant, 2020, Infection and Immunity
  • Immunodominant regions prediction of nucleocapsid protein for SARS-CoV-2 early diagnosis: a bioinformatics and immunoinformatics study, 2020, Pathogens and Global Health
  • Innate Lymphoid Cells Are Required for Endometrial Resistance to Chlamydia trachomatis Infection, 2020, Infection and Immunity
  • Gastrointestinal Coinfection Promotes Chlamydial Pathogenicity in the Genital Tract, 2020, Infection and Immunity

Frequent coauthors collaborating with Zhong include:

  • Yihui Wang
  • Huizhou Fan
  • Zengzi Zhou
  • Rongze He
  • Qi Tian

Zhong's works are most commonly published in these venues:

  • Infection and Immunity (20 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (9 publications)
  • Trends in Microbiology (2 publications)
  • Pathogens and Global Health (1 publication)
  • Acta Physico-Chimica Sinica (1 publication)

Best Publications

  • Inhibition of Apoptosis in Chlamydia-infected Cells: Blockade of Mitochondrial Cytochrome c Release and Caspase Activation

    Tao Fan;Hang Lu;He Hu;Lianfa Shi

  • Identification of a Chlamydial Protease–Like Activity Factor Responsible for the Degradation of Host Transcription Factors

    Guangming Zhong;Peiyi Fan;Hezhao Ji;Feng Dong

  • The atherogenic effects of chlamydia are dependent on serum cholesterol and specific to Chlamydia pneumoniae

    He Hu;Grant N. Pierce;Guangming Zhong

  • Chlamydia Inhibits Interferon γ–inducible Major Histocompatibility Complex Class II Expression by Degradation of Upstream Stimulatory Factor 1

    Guangming Zhong;Tao Fan;Li Liu

  • Degradation of Transcription Factor Rfx5 during the Inhibition of Both Constitutive and Interferon γ–Inducible Major Histocompatibility Complex Class I Expression in Chlamydia-Infected Cells

    Guangming Zhong;Li Liu;Tao Fan;Peiyi Fan

  • Production, specificity, and functionality of monoclonal antibodies to specific peptide–major histocompatibility complex class II complexes formed by processing of exogenous protein

    Guangming Zhong;Guangming Zhong;Caetano Reis e Sousa;Ronald N. Germain

  • Characterization of Fifty Putative Inclusion Membrane Proteins Encoded in the Chlamydia trachomatis Genome

    Zhongyu Li;Chaoqun Chen;Ding Chen;Yimou Wu

  • The Chlamydial Plasmid-Encoded Protein pgp3 Is Secreted into the Cytosol of Chlamydia-Infected Cells

    Zhongyu Li;Zhongyu Li;Ding Chen;Youmin Zhong;Shiping Wang

  • Activation of Raf/MEK/ERK/cPLA2 Signaling Pathway Is Essential for Chlamydial Acquisition of Host Glycerophospholipids

    Heng Su;Grant McClarty;Feng Dong;Grant M. Hatch

  • Related Leucine-based Cytoplasmic Targeting Signals in Invariant Chain and Major Histocompatibility Complex Class II Molecules Control Endocytic Presentation of Distinct Determinants in a Single Protein

    Guangming Zhong;Paola Romagnoli;Ronald N. Germain

  • Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection

    Wen Cheng;Pooja Shivshankar;Zhongyu Li;Lili Chen

  • ANTIGEN PRESENTATION BY MHC CLASS II MOLECULES : INVARIANT CHAIN FUNCTION,PROTEIN TRAFFICKING, AND THE MOLECULAR BASIS OF DIVERSE DETERMINANT CAPTURE

    Flora Castellino;Guangming Zhong;Ronald N Germain

  • Antigen-unspecific B Cells and Lymphoid Dendritic Cells Both Show Extensive Surface Expression of Processed Antigen–Major Histocompatibility Complex Class II Complexes after Soluble Protein Exposure In Vivo or In Vitro

    Guangming Zhong;Caetano Reis e Sousa;Ronald N. Germain

  • A Genome-Wide Profiling of the Humoral Immune Response to Chlamydia trachomatis Infection Reveals Vaccine Candidate Antigens Expressed in Humans

    Jie Wang;Yingqian Zhang;Chunxue Lu;Lei Lei

  • The secreted protease factor CPAF is responsible for degrading pro-apoptotic BH3-only proteins in Chlamydia trachomatis-infected cells

    Mustak Pirbhai;Feng Dong;Youmin Zhong;Kelvin Z. Pan

  • A live-attenuated chlamydial vaccine protects against trachoma in nonhuman primates

    Laszlo Kari;William M. Whitmire;Norma Olivares-Zavaleta;Morgan M. Goheen

  • Intranasal vaccination with a secreted chlamydial protein enhances resolution of genital Chlamydia muridarum infection, protects against oviduct pathology, and is highly dependent upon endogenous gamma interferon production.

    Ashlesh K. Murthy;James P. Chambers;Patricia A. Meier;Guangming Zhong

  • Tumor necrosis factor alpha production from CD8+ T cells mediates oviduct pathological sequelae following primary genital Chlamydia muridarum infection.

    Ashlesh K. Murthy;Weidang Li;Bharat Kumar Reddy Chaganty;Sangamithra Kamalakaran

  • Plasmid-Encoded Pgp3 Is a Major Virulence Factor for Chlamydia muridarum To Induce Hydrosalpinx in Mice

    Yuanjun Liu;Yuanjun Liu;Yumeng Huang;Zhangsheng Yang;Yina Sun

  • Degradation of the Proapoptotic Proteins Bik, Puma, and Bim with Bcl-2 Domain 3 Homology in Chlamydia trachomatis-Infected Cells

    Feng Dong;Mustak Pirbhai;Yangming Xiao;Youmin Zhong

  • Profiling of Human Antibody Responses to Chlamydia trachomatis Urogenital Tract Infection Using Microplates Arrayed with 156 Chlamydial Fusion Proteins

    Jyotika Sharma;Youmin Zhong;Feng Dong;Jeanna M. Piper

  • Chlamydia-Infected Cells Continue To Undergo Mitosis and Resist Induction of Apoptosis

    Whitney Greene;Yangming Xiao;Yanqing Huang;Grant McClarty

Frequent Co-Authors

Bernard P. Arulanandam
Bernard P. Arulanandam The University of Texas at San Antonio
Robert C. Brunham
Robert C. Brunham University of British Columbia
P. John Hart
P. John Hart The University of Texas Health Science Center at San Antonio
Ronald N. Germain
Ronald N. Germain National Institute of Allergy and Infectious Diseases
Jijie Chai
Jijie Chai Westlake University
Luis M. de la Maza
Luis M. de la Maza University of California, Irvine
Gerald I. Byrne
Gerald I. Byrne University of Tennessee Health Science Center
Wandy L. Beatty
Wandy L. Beatty Washington University in St. Louis
Richard P. Morrison
Richard P. Morrison University of Arkansas for Medical Sciences
Jing Wang
Jing Wang Tsinghua University

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