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Raphael H. Valdivia

Raphael H. Valdivia

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
15457
World Ranking
16953
National Ranking
6985

Overview

Raphael H. Valdivia is affiliated with Duke University in the United States and has a research focus spanning medicine, biochemistry, genetics and molecular biology, and immunology and microbiology. Their work reflects significant contributions to molecular biology, microbiology, epidemiology, immunology, and genetics.

The scientist's recent publications include several studies published in notable journals. These papers include: Genotypic and Phenotypic Diversity among Human Isolates of Akkermansia muciniphila (2021, mBio), A genetic system for Akkermansia muciniphila reveals a role for mucin foraging in gut colonization and host sterol biosynthesis gene expression (2023, Nature Microbiology), Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease (2022, Cell), The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction (2022, Cell Host & Microbe), and Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment (2022, Science Translational Medicine).

Valdivia's research covers a spectrum of topics, including:

  • Reproductive tract infections research
  • Gut microbiota and health
  • Urinary Tract Infections Management
  • Reproductive System and Pregnancy
  • Digestive system and related health
  • Diet and metabolism studies
  • Reproductive Physiology in Livestock

Frequent co-authors collaborating with Valdivia feature a group of researchers with substantial joint publication records. These include Lauren Davey, Lee Dolat, Robert J. Bastidas, Jessica R. McCann, and John F. Rawls.

The scientist's work has appeared repeatedly in key publication venues such as bioRxiv (Cold Spring Harbor Laboratory), mBio, Journal of Bacteriology, Cell Host & Microbe, and Current Opinion in Microbiology.

Valdivia's interdisciplinary research integrates insights from medicine and molecular biology to investigate complex biological processes related to microbiology and immune responses. Their publications and collaborations suggest a focus on understanding microbial interactions within human health contexts, especially relating to the gut microbiome and infectious diseases.

Best Publications

  • FACS-optimized mutants of the green fluorescent protein (GFP)

    Brendan P. Cormack;Raphael H. Valdivia;Stanley Falkow;Stanley Falkow

  • Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes

    Andrés Vazquez-Terres;Jessica Jones-Carson;Andreas J. Bäumler;Stanley Falkow

  • Macrophage‐dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival

    Daniela Maria Cirillo;Raphael H. Valdivia;Denise M. Monack;Stanley Falkow

  • Fluorescence-Based Isolation of Bacterial Genes Expressed Within Host Cells

    Raphael H. Valdivia;Stanley Falkow

  • Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction.

    Raphael H. Valdivia;Stanley Falkow;Stanley Falkow

  • Applications for green fluorescent protein (GFP) in the study of host-pathogen interactions.

    Raphael H. Valdivia;Alexander E. Hromockyj;Denise Monack;Lalita Ramakrishnan

  • Cytoplasmic lipid droplets are translocated into the lumen of the Chlamydia trachomatis parasitophorous vacuole

    Jordan L. Cocchiaro;Yadunanda Kumar;Elizabeth R. Fischer;Ted Hackstadt

  • Chlamydial Intracellular Survival Strategies

    Robert J. Bastidas;Cherilyn A. Elwell;Joanne N. Engel;Raphael H. Valdivia

  • The obligate intracellular pathogen Chlamydia trachomatis targets host lipid droplets.

    Yadunanda Kumar;Jordan Cocchiaro;Raphael H. Valdivia

  • The Yeast Clathrin Adaptor Protein Complex 1 Is Required for the Efficient Retention of a Subset of Late Golgi Membrane Proteins

    Raphael H. Valdivia;Daniel Baggott;John S. Chuang;Randy W. Schekman

  • Emerging Roles for Lipid Droplets in Immunity and Host-Pathogen Interactions

    Hector Alex Saka;Raphael Valdivia

  • Actin and intermediate filaments stabilize the Chlamydia trachomatis vacuole by forming dynamic structural scaffolds

    Yadunanda Kumar;Raphael H. Valdivia

  • STING-Dependent Recognition of Cyclic di-AMP Mediates Type I Interferon Responses during Chlamydia trachomatis Infection

    Jeffrey R. Barker;Benjamin J. Koestler;Victoria K. Carpenter;Dara L. Burdette

  • Quantitative proteomics reveals metabolic and pathogenic properties of Chlamydia trachomatis developmental forms

    Hector A. Saka;J. Will Thompson;Yi Shan Chen;Yadunanda Kumar

  • Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection.

    Kathleen M. Mirrashidi;Cherilyn A. Elwell;Erik Verschueren;Erik Verschueren;Jeffrey R. Johnson;Jeffrey R. Johnson

  • Chlamydia effector proteins and new insights into chlamydial cellular microbiology.

    Raphael H Valdivia

  • The yeasts Rho1p and Pkc1p regulate the transport of chitin synthase III (Chs3p) from internal stores to the plasma membrane

    Raphael H. Valdivia;Randy Schekman

  • IRG and GBP Host Resistance Factors Target Aberrant, “Non-self” Vacuoles Characterized by the Missing of “Self” IRGM Proteins

    Arun K. Haldar;Hector Alex Saka;Anthony S. Piro;Joe Dan Dunn

  • Virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis revealed by forward genetic approaches

    Bidong D. Nguyen;Raphael H. Valdivia

  • Leading a sheltered life: intracellular pathogens and maintenance of vacuolar compartments.

    Yadunanda Kumar;Raphael H. Valdivia

Frequent Co-Authors

Stanley Falkow
Stanley Falkow Stanford University
John F. Rawls
John F. Rawls Duke University
Guido Kroemer
Guido Kroemer Université Paris Cité
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco
Lalita Ramakrishnan
Lalita Ramakrishnan University of Cambridge
Gregory A. Taylor
Gregory A. Taylor Duke University
Joseph Heitman
Joseph Heitman Duke University
Denise M. Monack
Denise M. Monack Stanford University
Gail P. Jarvik
Gail P. Jarvik University of Washington
Dirk Bumann
Dirk Bumann University of Basel

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