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Immunology

D-Index
44
Citations
6879
World Ranking
4798
National Ranking
2152

Overview

Luis M. de la Maza is affiliated with the University of California, Irvine in the United States and has a research focus primarily situated in immunology, microbiology, and medicine. Their work spans various subfields, including microbiology, epidemiology, immunology, surgery, and ecology. The scientist's main areas of research include reproductive tract infections, cervical cancer and HPV, genital health and disease, immune response and inflammation, bacterial infections and vaccines, hepatitis B virus studies, and urinary tract infections management.

Frequent collaborators in their research include Sukumar Pal, Matthew A. Coleman, Delia F. Tifrea, Sean F. Gilmore, and Amy Rasley. Their research output is published predominantly in specialized journals focusing on vaccines and infectious diseases. The key publication venues frequently featuring their work are:

  • npj Vaccines
  • Vaccines
  • Pathogens
  • PLoS ONE
  • bioRxiv (Cold Spring Harbor Laboratory)

Their recent significant publications highlight various aspects of vaccine development and infectious disease protection strategies. These include:

  • A modular vaccine platform enabled by decoration of bacterial outer membrane vesicles with biotinylated antigens (2023, Nature Communications)
  • Chlamydia trachomatis vaccines for genital infections: where are we and how far is there to go? (2021, Expert Review of Vaccines)
  • Vaccination with the recombinant major outer membrane protein elicits long-term protection in mice against vaginal shedding and infertility following a Chlamydia muridarum genital challenge (2020, npj Vaccines)
  • Improved protection against Chlamydia muridarum using the native major outer membrane protein trapped in Resiquimod-carrying amphipols and effects in protection with addition of a Th1 (CpG-1826) and a Th2 (Montanide ISA 720) adjuvant (2020, Vaccine)
  • Protection against a chlamydial respiratory challenge by a chimeric vaccine formulated with the Chlamydia muridarum major outer membrane protein variable domains using the Neisseria lactamica porin B as a scaffold (2020, npj Vaccines)

The scientist's research addresses key challenges in vaccine formulation and efficacy, particularly concerning Chlamydia species and related bacterial infections. Their output reflects a sustained contribution to understanding immune responses and advancing vaccine development.

Best Publications

  • Chlamydia infections and heart disease linked through antigenic mimicry.

    Kurt Bachmaier;Kurt Bachmaier;Nikolaus Neu;Luis M. de la Maza;Sukumar Pal

  • Imaging of Effector Memory T Cells during a Delayed-Type Hypersensitivity Reaction and Suppression by Kv1.3 Channel Block

    Melanie P. Matheu;Christine Beeton;Adriana Garcia;Victor Chi

  • Vaccination with the Chlamydia trachomatis Major Outer Membrane Protein Can Elicit an Immune Response as Protective as That Resulting from Inoculation with Live Bacteria

    Sukumar Pal;Ellena M. Peterson;Luis M. de la Maza

  • The 7.5-kb plasmid present in Chlamydia trachomatis is not essential for the growth of this microorganism.

    Ellena M. Peterson;Brian A. Markoff;Julius Schachter;Luis M. de la Maza

  • Adeno-associated virus autointerference

    Barrie J. Carter;Catherine A. Laughlin;Luis M. de la Maza;Maureen Myers

  • Chlamydia trachomatis Native Major Outer Membrane Protein Induces Partial Protection in Nonhuman Primates: Implication for a Trachoma Transmission-Blocking Vaccine

    Laszlo Kari;William M. Whitmire;Deborah D. Crane;Nathalie Reveneau

  • Update on Chlamydia trachomatis Vaccinology.

    Luis M. de la Maza;Guangming Zhong;Robert C. Brunham

  • Monoclonal immunoglobulin A antibody to the major outer membrane protein of the Chalamydia trachomatis mouse pneumonitis biovar protects mice against a chlamydial genital challenge

    Sukumar Pal;Ida Theodor;Ellena M. Peterson;Luis M. de la Maza

  • Immunization with the Chlamydia trachomatis mouse pneumonitis major outer membrane protein can elicit a protective immune response against a genital challenge.

    Sukumar Pal;I. D. A. Theodor;Ellena M. Peterson;Luis M. De La Maza

  • Vaccination of mice with DNA plasmids coding for the Chlamydia trachomatis major outer membrane protein elicits an immune response but fails to protect against a genital challenge.

    Sukumar Pal;Kerry M Barnhart;Qun Wei;Anna M Abai

  • Protection against infertility in a BALB/c mouse salpingitis model by intranasal immunization with the mouse pneumonitis biovar of Chlamydia trachomatis.

    Sukumar Pal;T. J. Fielder;E. M. Peterson;L. M. De La Maza

  • Targeting the inhibitory receptor CTLA-4 on T cells increased abscopal effects in murine mesothelioma model

    Licun Wu;Matthew Onn Wu;Luis De la Maza;Zhihong Yun

  • A new computer model for estimating the impact of vaccination protocols and its application to the study of Chlamydia trachomatis genital infections.

    Michael A. de la Maza;Luis M. de la Maza

  • Structural and Functional Analyses of the Major Outer Membrane Protein of Chlamydia trachomatis

    Guifeng Sun;Sukumar Pal;Annahita K. Sarcon;Soyoun Kim

  • Vaccines for Chlamydia trachomatis infections.

    Luis M de la Maza;Ellena M Peterson

  • Up-regulation of the JAK/STAT1 signal pathway during Chlamydia trachomatis infection.

    Sonya P. Lad;Elaine Y. Fukuda;Jiali Li;Luis M. de la Maza

  • Temporal expression of type III secretion genes of Chlamydia pneumoniae.

    Anatoly Slepenkin;Vladimir Motin;Luis M. de la Maza;Ellena M. Peterson

  • Reversal of the Antichlamydial Activity of Putative Type III Secretion Inhibitors by Iron

    Anatoly Slepenkin;Per-Anders Enquist;Ulrik Hägglund;Luis M. de la Maza

  • Screening of Urine Cultures by Three Automated Systems

    Marie T. Pezzlo;Grace L. Tan;Ellena M. Peterson;Luis M. De La Maza

  • Functional and structural mapping of Chlamydia trachomatis species-specific major outer membrane protein epitopes by use of neutralizing monoclonal antibodies.

    E. M. Peterson;Xun Cheng;B. A. Markoff;T. J. Fielder

  • Immunization with the Chlamydia trachomatis major outer membrane protein, using adjuvants developed for human vaccines, can induce partial protection in a mouse model against a genital challenge.

    Sukumar Pal;Ellena M. Peterson;Rino Rappuoli;Giulio Ratti

  • Protection against an intranasal challenge by vaccines formulated with native and recombinant preparations of the Chlamydia trachomatis major outer membrane protein

    Guifeng Sun;Sukumar Pal;Joseph Weiland;Ellena M. Peterson

  • Role of endogenous gamma interferon in host defense against Chlamydia trachomatis infections.

    Guangming Zhong;E. M. Peterson;C. W. Czarniecki;R. D. Schreiber

  • Immunization with the Chlamydia trachomatis Mouse Pneumonitis Major Outer Membrane Protein by Use of CpG Oligodeoxynucleotides as an Adjuvant Induces a Protective Immune Response against an Intranasal Chlamydial Challenge

    Sukumar Pal;Heather L. Davis;Ellena M. Peterson;Luis M. de la Maza

  • Factors influencing the induction of infertility in a mouse model of Chlamydia trachomatis ascending genital tract infection

    Sukumar Pal;Wei Hui;Ellena M. Peterson;Luis M. De La Maza

Frequent Co-Authors

Ellena M. Peterson
Ellena M. Peterson University of California, Irvine
Marc de Perrot
Marc de Perrot University of Toronto
Philip L. Felgner
Philip L. Felgner University of California, Irvine
Peter A. Barry
Peter A. Barry Royal Marsden NHS Foundation Trust
Pierre Baldi
Pierre Baldi University of California, Irvine
Deborah Dean
Deborah Dean University of California, San Francisco
Guangming Zhong
Guangming Zhong The University of Texas Health Science Center at San Antonio
Servaas A. Morré
Servaas A. Morré Maastricht University
David M. Ojcius
David M. Ojcius University of the Pacific
Nicholas R. Thomson
Nicholas R. Thomson Wellcome Sanger Institute

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