World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
54
Citations
17605
World Ranking
12444
National Ranking
3317

Research.com Recognitions

  • 2000 - Fellow of Alfred P. Sloan Foundation

Overview

K. A. Woerpel is affiliated with New York University in the United States and has established a research profile primarily in the fields of Chemistry and Materials Science. Their work spans various subfields including Materials Chemistry, Organic Chemistry, Molecular Biology, Inorganic Chemistry, and Physical and Theoretical Chemistry.

The scientist's research interests and main topics covered include:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Asymmetric Synthesis and Catalysis
  • Synthetic Organic Chemistry Methods
  • Carbohydrate Chemistry and Synthesis
  • Oxidative Organic Chemistry Reactions
  • Chemical Synthesis and Reactions

K. A. Woerpel has contributed extensively to scientific publications with a focus on crystallography and organic chemistry. Their frequent publication venues include:

  • The Cambridge Structural Database
  • Organic Letters
  • The Journal of Organic Chemistry
  • Angewandte Chemie International Edition
  • Synthesis

Notable recent papers by Woerpel include:

  • Identification of essential sites of lipid peroxidation in ferroptosis, 2023, Nature Chemical Biology
  • Reactions of Allylmagnesium Reagents with Carbonyl Compounds and Compounds with CN Double Bonds: Their Diastereoselectivities Generally Cannot Be Analyzed Using the Felkin-Anh and Chelation-Control Models, 2020, Chemical Reviews
  • Strain-Promoted Oxidation of Methylenecyclopropane Derivatives using N-Hydroxyphthalimide and Molecular Oxygen in the Dark, 2020, Organic Letters
  • Halogen Atom Participation in Guiding the Stereochemical Outcomes of Acetal Substitution Reactions, 2022, Angewandte Chemie International Edition
  • Diastereoselective Additions of Allylmagnesium Reagents to α-Substituted Ketones When Stereochemical Models Cannot Be Used, 2021, The Journal of Organic Chemistry

Woerpel has collaborated frequently with several colleagues, indicating a network of active research partnerships. Frequent coauthors include:

  • Krystyna M. Demkiw
  • Chunhua Hu
  • Nicole D. Bartolo
  • Elizabeth M. Valentín
  • Collin H. Witt

Among their recognitions, K. A. Woerpel received the designation of Fellow of the Alfred P. Sloan Foundation in 2000.

Best Publications

  • Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

    Brent R. Stockwell;José Pedro Friedmann Angeli;Hülya Bayir;Ashley I. Bush

  • Bis(oxazolines) as chiral ligands in metal-catalyzed asymmetric reactions. Catalytic, asymmetric cyclopropanation of olefins

    David A. Evans;Keith A. Woerpel;Mira M. Hinman;Margaret M. Faul

  • FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation.

    Michael M. Gaschler;Alexander A. Andia;Hengrui Liu;Joleen M. Csuka

  • Stereochemistry of Nucleophilic Substitution Reactions Depending upon Substituent: Evidence for Electrostatic Stabilization of Pseudoaxial Conformers of Oxocarbenium Ions by Heteroatom Substituents

    Leticia Ayala;Claudia G Lucero;Jan Antoinette C Romero;Sarah A Tabacco

  • A Stereoelectronic Model To Explain the Highly Stereoselective Reactions of Nucleophiles with Five-Membered-Ring Oxocarbenium Ions

    Catharine H. Larsen;Brian H. Ridgway;Jared T. Shaw;K. A. Woerpel

  • Stereochemical Reversal of Nucleophilic Substitution Reactions Depending upon Substituent: Reactions of Heteroatom-Substituted Six-Membered-Ring Oxocarbenium Ions through Pseudoaxial Conformers

    Jan Antoinette C. Romero;Sarah A. Tabacco;K. A. Woerpel

  • Stereoselective C-Glycosylation Reactions of Ribose Derivatives: Electronic Effects of Five-Membered Ring Oxocarbenium Ions

    Catharine H. Larsen;Brian H. Ridgway;Jared T. Shaw;Deborah M. Smith

  • ‘Bis(oxazolines)’ as Ligands for Self‐Assembling Chiral Coordination Polymers— Structure of a Copper(I) Catalyst for the Enantioselective Cyclopropanation of Olefins

    David A. Evans;Keith A. Woerpel;Michael J. Scott

  • An Improved Procedure for the Preparation of 2,2-Bis[2-[4(S)- tert-butyl-1,3-oxazolinyl]]propane [(S,S)-tert-Butylbis(oxazoline)] and Derived Copper(II) Complexes

    David A. Evans;Gretchen S. Peterson;Jeffrey S. Johnson;David M. Barnes

  • Five-Membered Ring Peroxide Selectively Initiates Ferroptosis in Cancer Cells

    Rachel P. Abrams;William L. Carroll;K. A. Woerpel

  • Stereoselective C-glycosylation reactions of pyranoses: the conformational preference and reactions of the mannosyl cation.

    Claudia G. Lucero;K. A. Woerpel

  • Transmetalation of Alkylboranes to Palladium in the Suzuki Coupling Reaction Proceeds with Retention of Stereochemistry

    Brian H. Ridgway;K. A. Woerpel

  • Oxidation of Sterically Hindered Alkoxysilanes and Phenylsilanes under Basic Conditions

    Jacqueline H. Smitrovich;K. A. Woerpel

  • Electrostatic interactions in cations and their importance in biology and chemistry.

    Deborah M. Smith;K. A. Woerpel

  • The effect of electrostatic interactions on conformational equilibria of multiply substituted tetrahydropyran oxocarbenium ions.

    Michael T. Yang;K. A. Woerpel

  • Erosion of stereochemical control with increasing nucleophilicity: O-glycosylation at the diffusion limit.

    Matthew G. Beaver;K. A. Woerpel

  • Nucleophilic additions to fused bicyclic five-membered ring oxocarbenium ions: evidence for preferential attack on the inside face.

    Deborah M. Smith;Michelle B. Tran;K. A. Woerpel

  • Structural evidence that alkoxy substituents adopt electronically preferred pseudoaxial orientations in six-membered ring dioxocarbenium ions

    Stephen Chamberland;Joseph W. Ziller;K. A. Woerpel

  • Development of reactions of silacyclopropanes as new methods for stereoselective organic synthesis.

    Annaliese K. Franz;K. A. Woerpel

  • 13C NMR spectroscopy for the quantitative determination of compound ratios and polymer end groups.

    Douglas A L Otte;Dorothee E. Borchmann;Chin Lin;Marcus Weck

  • Synthesis and reactivity of an iridium hydroxo complex. Insertion of ethylene into a metal-oxygen bond

    K. A. Woerpel;Robert G. Bergman

Frequent Co-Authors

David A. Evans
David A. Evans Harvard University
Chunhua Hu
Chunhua Hu New York University
Oliver Reiser
Oliver Reiser University of Regensburg
Jon Clardy
Jon Clardy Harvard University
Joseph W. Ziller
Joseph W. Ziller University of California, Irvine
Thomas Anderson
Thomas Anderson University of Washington
Valerian E. Kagan
Valerian E. Kagan University of Pittsburgh
Jeffrey S. Johnson
Jeffrey S. Johnson University of North Carolina at Chapel Hill
Antonio A. Romero
Antonio A. Romero Spanish National Research Council
Brent R. Stockwell
Brent R. Stockwell Columbia University

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