Yung-Chi Cheng

Overview

Best Publications

• Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction.

  Cheng Y;Prusoff Wh

  17152
  Citations

• Antisense oligonucleotides as therapeutic agents--is the bullet really magical?

  CA Stein;YC Cheng

  1809
  Citations

• Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells.

  Michael Wigler;Saul Silverstein;Lih-Syng Lee;Angel Pellicer

  1763
  Citations

• A unified model for the flicker noise in metal-oxide-semiconductor field-effect transistors

  K.K. Hung;P.K. Ko;C. Hu;Y.C. Cheng

  1104
  Citations

• Inhibition of the replication of hepatitis B virus in vitro by 2',3'-dideoxy-3'-thiacytidine and related analogues.

  Shin-Lian Doong;Ching-Hwa Tsai;Raymond F. Schinazi;Dennis C. Liotta

  832
  Citations

• Metabolism and mechanism of action of 5-fluorouracil

  William B. Parker;Yung Chi Cheng

  576
  Citations

• Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity

  Rick Avery Finch;Mao Chin Liu;Susan P. Grill;William C. Rose

  453
  Citations

• Threshold voltage model for deep-submicrometer MOSFETs

  Z.-H. Liu;C. Hu;J.-H. Huang;T.-Y. Chan

  441
  Citations

• Random telegraph noise of deep-submicrometer MOSFETs

  K.K. Hung;P.K. Ko;C. Hu;Y.C. Cheng

  430
  Citations

• The Four-Herb Chinese Medicine PHY906 Reduces Chemotherapy-Induced Gastrointestinal Toxicity

  Wing Lam;Scott Bussom;Fulan Guan;Zaoli Jiang

  407
  Citations

• Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2',3'-dideoxycytidine.

  C H Chen;Y C Cheng

  392
  Citations

• Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity.

  Chin-Ho Chen;M. Vazquez-Padua;Yung-Chi Cheng

  391
  Citations

• Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2',3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication.

  C.N. Chang;S.L. Doong;J.H. Zhou;J.W. Beach

  355
  Citations

• A physics-based MOSFET noise model for circuit simulators

  K.K. Hung;P.K. Ko;C. Hu;Y.C. Cheng

  339
  Citations

• Human immunodeficiency virus reverse transcriptase. General properties and its interactions with nucleoside triphosphate analogs.

  Y C Cheng;G E Dutschman;K F Bastow;M G Sarngadharan

  334
  Citations

• Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNase H: implications for antisense technology.

  Wen-Yi Gao;Fu-Sheng Han;C. Storm;W. Egan

  328
  Citations

• Unique spectrum of activity of 9-[(1,3-dihydroxy-2-propoxy)methyl]-guanine against herpesviruses in vitro and its mode of action against herpes simplex virus type 1

  Yung-Chi Cheng;Eng-Shang Huang;Jung-Chung Lin;Eng-Chun Mar

  326
  Citations

• Use of 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil as a novel antiviral agent for hepatitis B virus and Epstein-Barr virus.

  C K Chu;T Ma;K Shanmuganathan;C Wang

  319
  Citations

• Biochemical pharmacology of (+)- and (-)-2',3'-dideoxy-3'- thiacytidine as anti-hepatitis B virus agents

  C N Chang;V Skalski;J H Zhou;Y C Cheng

  316
  Citations

• Cellular metabolism of 2',3'-dideoxycytidine, a compound active against human immunodeficiency virus in vitro.

  M. C. Starnes;Yung-Chi Cheng

  303
  Citations