D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 106 Citations 55,582 615 World Ranking 795 National Ranking 515

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • DNA

Yung-Chi Cheng spends much of his time researching Biochemistry, Molecular biology, DNA, DNA polymerase and Enzyme. His Molecular biology research also works with subjects such as

  • Virus and related Reverse transcriptase,
  • DNA synthesis, which have a strong connection to Deoxycytidine kinase. Yung-Chi Cheng combines subjects such as Base excision repair, DNA clamp, Polymerase, DNA polymerase II and DNA replication with his study of DNA polymerase.

His studies deal with areas such as HeLa and Stereochemistry as well as Enzyme. The various areas that he examines in his Stereochemistry study include Etoposide, Topoisomerase, Topoisomerase-II Inhibitor and Chemical synthesis. He has included themes like In vitro, Cytotoxicity and Cell growth in his Virology study.

His most cited work include:

  • Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. (11279 citations)
  • Antisense oligonucleotides as therapeutic agents--is the bullet really magical? (1329 citations)
  • Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells. (1245 citations)

What are the main themes of his work throughout his whole career to date?

Yung-Chi Cheng mainly focuses on Biochemistry, Stereochemistry, Molecular biology, Virology and Virus. His is involved in several facets of Biochemistry study, as is seen by his studies on Enzyme, DNA, Nucleoside, Kinase and Thymidine. His study explores the link between Stereochemistry and topics such as Cytotoxicity that cross with problems in Topoisomerase.

The study incorporates disciplines such as Cell culture, HeLa, DNA synthesis and DNA polymerase in addition to Molecular biology. His DNA polymerase research includes themes of DNA polymerase II, Polymerase and DNA clamp. His Virology research is multidisciplinary, relying on both Nucleoside analogue and Reverse transcriptase.

He most often published in these fields:

  • Biochemistry (28.61%)
  • Stereochemistry (22.16%)
  • Molecular biology (22.44%)

What were the highlights of his more recent work (between 2006-2021)?

  • Internal medicine (3.65%)
  • Biochemistry (28.61%)
  • Pharmacology (7.15%)

In recent papers he was focusing on the following fields of study:

Yung-Chi Cheng mostly deals with Internal medicine, Biochemistry, Pharmacology, Traditional Chinese medicine and Stereochemistry. His Biochemistry research is multidisciplinary, incorporating perspectives in Molecular biology and Stavudine. His Molecular biology research incorporates themes from Cell culture, Clonogenic assay, Virus, Virology and DNA.

The concepts of his Pharmacology study are interwoven with issues in Apoptosis, Scutellaria baicalensis, Toxicity and In vivo. His studies examine the connections between Stereochemistry and genetics, as well as such issues in Cytotoxicity, with regards to Biological activity. His Pyrimidine analogue research extends to Enzyme, which is thematically connected.

Between 2006 and 2021, his most popular works were:

  • The Four-Herb Chinese Medicine PHY906 Reduces Chemotherapy-Induced Gastrointestinal Toxicity (223 citations)
  • Nucleoplasmic calcium is required for cell proliferation. (99 citations)
  • Simple and convenient G-quadruplex-based turn-on fluorescence assay for 3' → 5' exonuclease activity. (97 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

His primary scientific interests are in Chromatography, Internal medicine, Biochemistry, Traditional medicine and Molecular biology. In the field of Biochemistry, his study on Secretion, Peptidoglycan and Chemokine overlaps with subjects such as TLR2 and Butyrate. His Molecular biology study integrates concerns from other disciplines, such as Deoxyribonucleotide Triphosphate, Nucleoside Reverse Transcriptase Inhibitor, Virology, Mitochondrial toxicity and DNA.

His Nucleoside Reverse Transcriptase Inhibitor research is multidisciplinary, incorporating elements of Zidovudine, Deoxyadenosine, Enzyme, Intracellular and Metabolism. His research in DNA intersects with topics in Reverse transcriptase, RNase H and Guanine. Yung-Chi Cheng performs multidisciplinary studies into Scaffold and Stereochemistry in his work.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction.

Cheng Y;Prusoff Wh.
Biochemical Pharmacology (1973)

16665 Citations

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells.

Michael Wigler;Saul Silverstein;Lih-Syng Lee;Angel Pellicer.
Cell (1977)

1759 Citations

Antisense oligonucleotides as therapeutic agents--is the bullet really magical?

CA Stein;YC Cheng.
Science (1993)

1757 Citations

A unified model for the flicker noise in metal-oxide-semiconductor field-effect transistors

K.K. Hung;P.K. Ko;C. Hu;Y.C. Cheng.
IEEE Transactions on Electron Devices (1990)

1008 Citations

Inhibition of the replication of hepatitis B virus in vitro by 2',3'-dideoxy-3'-thiacytidine and related analogues.

Shin-Lian Doong;Ching-Hwa Tsai;Raymond F. Schinazi;Dennis C. Liotta.
Proceedings of the National Academy of Sciences of the United States of America (1991)

825 Citations

Metabolism and mechanism of action of 5-fluorouracil

William B. Parker;Yung Chi Cheng.
Pharmacology & Therapeutics (1990)

525 Citations

Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity

Rick Avery Finch;Mao Chin Liu;Susan P. Grill;William C. Rose.
Biochemical Pharmacology (2000)

426 Citations

Threshold voltage model for deep-submicrometer MOSFETs

Z.-H. Liu;C. Hu;J.-H. Huang;T.-Y. Chan.
IEEE Transactions on Electron Devices (1993)

416 Citations

Random telegraph noise of deep-submicrometer MOSFETs

K.K. Hung;P.K. Ko;C. Hu;Y.C. Cheng.
IEEE Electron Device Letters (1990)

406 Citations

Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2',3'-dideoxycytidine.

C H Chen;Y C Cheng.
Journal of Biological Chemistry (1989)

388 Citations

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