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Chemistry

D-Index
62
Citations
11391
World Ranking
9004
National Ranking
2549

Overview

Kenneth F. Bastow is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Bastow's work includes considerable contributions in the subfields of Molecular Biology, Organic Chemistry, Pharmacology, Plant Science, and Oncology.

Their scientific output has been published extensively in venues including UNC Libraries, OPAL (Open@LaTrobe) (La Trobe University), and Molecules. Bastow's publications reflect a focus on synthesis, biological activity, and phytochemistry related to various organic compounds and natural products.

Frequent topics in Bastow's research include:

  • Synthesis of Organic Compounds
  • Synthesis and biological activity
  • Ginseng Biological Effects and Applications
  • Multicomponent Synthesis of Heterocycles
  • Phytochemistry and biological activities of Ficus species
  • Biological Activity of Diterpenoids and Biflavonoids
  • Phytochemistry and Biological Activities

Bastow has collaborated regularly with several researchers, including:

  • Kuo Hsiung Lee
  • Kyoko Nakagawa-Goto
  • Kuo-Hsiung Lee
  • Susan L. Morris-Natschke
  • Yizhou Dong

Selected recent publications by Kenneth F. Bastow include:

  • "Elecanacin, a Novel New Naphthoquinone from the Bulb of Eleutherine americana," 2021, UNC Libraries
  • "Identification of Novel 4'-O-Demethyl-epipodophyllotoxin Derivatives as Antitumor Agents Targeting Topoisomerase II," 2022, Molecules
  • "Cytotoxic Polyisoprenyl Benzophenonoids from Garcinia subelliptica," 2020, UNC Libraries
  • "Antitumor Agents. 272. Structure−Activity Relationships and In Vivo Selective Anti-Breast Cancer Activity of Novel Neo-tanshinlactone Analogues," 2020, OPAL (Open@LaTrobe) (La Trobe University)
  • "Antitumor agents 278. 4-Amino-2H-benzo[h]chromen-2-one (ABO) analogs as potent in vitro anti-cancer agents," 2020, UNC Libraries

Best Publications

  • 6-Alkylamino- and 2,3-dihydro-3'-methoxy-2-phenyl-4-quinazolinones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.

    Mann-Jen Hour;Li-Jiau Huang;Sheng-Chu Kuo;Yi Xia

  • Human immunodeficiency virus reverse transcriptase. General properties and its interactions with nucleoside triphosphate analogs.

    Y C Cheng;G E Dutschman;K F Bastow;M G Sarngadharan

  • Antitumor Agents. 181. † Synthesis and Biological Evaluation of 6,7,2',3',4'-Substituted-1,2,3,4-tetrahydro-2-phenyl-4-quinolones as a New Class of Antimitotic Antitumor Agents

    Yi Xia;Zheng Yu Yang;Peng Xia;Kenneth F. Bastow

  • Antitumor Agents. 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza.

    Xihong Wang;Kenneth F. Bastow;Chang Ming Sun;Yun Lian Lin

  • Antitumor Agents. Part 204: Synthesis and Biological Evaluation of Substituted 2-Aryl Quinazolinones

    Yi Xia;Zheng Yu Yang;Mann Jen Hour;Sheng Chu Kuo

  • Cytotoxic and antimalarial β-carboline alkaloids from the roots of Eurycoma longifolia

    Ping Chung Kuo;Li Shian Shi;Amooru G. Damu;Chung Ren Su

  • Identification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition.

    James S. Gibbs;Henry C. Chiou;Kenneth F. Bastow;Yung-Chi Cheng

  • Antitumor Agents. 250.† Design and Synthesis of New Curcumin Analogues as Potential Anti-Prostate Cancer Agents

    Li Lin;Qian Shi;Alexander K. Nyarko;Kenneth F. Bastow

  • Antitumor agents 201.1 Cytotoxicity of harmine and β-carboline analogs

    Junko Ishida;Hui Kang Wang;Kenneth F. Bastow;Chang Qi Hu

  • Antitumor agents. Part 214: synthesis and evaluation of curcumin analogues as cytotoxic agents.

    Junko Ishida;Hironori Ohtsu;Yoko Tachibana;Yuka Nakanishi

  • Metabolism of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new anti-herpes virus compound, in herpes simplex virus-infected cells.

    Y C Cheng;S P Grill;G E Dutschman;K Nakayama

  • Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.

    Masataka Itoigawa;Yoshiki Kashiwada;Chihiro Ito;Hiroshi Furukawa

  • Simple isoquinoline and benzylisoquinoline alkaloids as potential antimicrobial, antimalarial, cytotoxic, and anti-HIV agents.

    Kinuko Iwasa;Masataka Moriyasu;Yoko Tachibana;Hye Sook Kim

  • Antitumor agents 200. Cytotoxicity of naturally occurring resveratrol oligomers and their acetate derivatives.

    Masayoshi Ohyama;Toshiyuki Tanaka;Tetsuro Ito;Munekazu Iinuma

  • Prenylated Benzophenones and Xanthones from Hypericum scabrum

    Naonobu Tanaka;Yoshihisa Takaishi;Yasuhiro Shikishima;Yuka Nakanishi

  • Tannins as Potent Inhibitors of DNA Topoisomerase II In Vitro

    Yoshiki Kashiwada;Gen-Ichiro Nonaka;Itsuo Nishioka;Kenneth Jiann-Hung Lee;Kenneth Jiann-Hung Lee

  • Isolation, Structures, and Structure−Cytotoxic Activity Relationships of Withanolides and Physalins from Physalis angulata

    Amooru G. Damu;Ping Chung Kuo;Chung Ren Su;Tsung Hsiao Kuo

  • Characterization of the DNA polymerases induced by a group of herpes simplex virus type I variants selected for growth in the presence of phosphonoformic acid.

    D Derse;K F Bastow;Y Cheng

  • Antitumor Agents. 228. Five New Agarofurans, Reissantins A−E, and Cytotoxic Principles from Reissantia buchananii

    Fang-Rong Chang;Ken-Ichiro Hayashi;I-Hsiao Chen;Chih-Chuang Liaw

  • Anti-HBV and cytotoxic activities of pyranocoumarin derivatives.

    Chung Ren Su;Sheau Farn Yeh;Chih Miem Liu;Amooru G. Damu

  • Novel mechanisms of DNA topoisomerase II inhibition by pyranonaphthoquinone derivatives—eleutherin, α lapachone, and β lapachone∗

    Preethi Krishnan;Kenneth F Bastow

Frequent Co-Authors

Kuo Hsiung Lee
Kuo Hsiung Lee University of Minnesota
Susan L. Morris-Natschke
Susan L. Morris-Natschke University of North Carolina at Chapel Hill
Tian Shung Wu
Tian Shung Wu National Cheng Kung University
Yung-Chi Cheng
Yung-Chi Cheng Yale University
Fang Rong Chang
Fang Rong Chang Kaohsiung Medical University
Yang Chang Wu
Yang Chang Wu China Medical University
Ernest Hamel
Ernest Hamel National Institutes of Health
Sheng-Chu Kuo
Sheng-Chu Kuo China Medical University
Yoshiki Kashiwada
Yoshiki Kashiwada University of Tokushima
Ken-ichiro Hayashi
Ken-ichiro Hayashi Okayama University of Science

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