Stereochemistry, Pharmacology, Biochemistry, Cytotoxicity and Chemical synthesis are his primary areas of study. The various areas that he examines in his Stereochemistry study include Biological activity, 1,4-Naphthoquinone, Structure–activity relationship and Mechanism of action. His Pharmacology study incorporates themes from Superoxide, Nitric oxide, Immunology and Soluble guanylyl cyclase.
As a member of one scientific family, Sheng-Chu Kuo mostly works in the field of Biochemistry, focusing on Platelet and, on occasion, Phosphodiesterase. His Cytotoxicity study results in a more complete grasp of In vitro. His In vitro research is multidisciplinary, relying on both Cell culture and Aryl.
Sheng-Chu Kuo spends much of his time researching Stereochemistry, Pharmacology, Apoptosis, Cancer research and Biochemistry. The Stereochemistry study combines topics in areas such as Lead compound, In vitro, Chemical synthesis and Cytotoxicity. His work deals with themes such as Cell culture and Structure–activity relationship, which intersect with Cytotoxicity.
His biological study spans a wide range of topics, including Platelet and Mechanism of action. The study incorporates disciplines such as Molecular biology, Cell growth and Cell biology in addition to Apoptosis. His study in Cancer research is interdisciplinary in nature, drawing from both Cancer cell, Cancer, Internal medicine and Protein kinase B.
Sheng-Chu Kuo focuses on Cancer research, Pharmacology, Apoptosis, Cancer cell and Cell cycle. His Cancer research research integrates issues from Cyclin-dependent kinase 1, Curcumin, Breast cancer and In vivo. Sheng-Chu Kuo interconnects Cell culture, Mechanism of action, Potency, Cytotoxicity and Structure–activity relationship in the investigation of issues within Pharmacology.
Sheng-Chu Kuo has researched Apoptosis in several fields, including Indazole, Signal transduction, Cell biology and Cell growth. His Cell biology research includes elements of Molecular biology and Programmed cell death. His studies in Stereochemistry integrate themes in fields like Lead compound and Methylenedioxy.
His primary areas of study are Pharmacology, Apoptosis, Cancer research, Cell biology and Cancer cell. The concepts of his Pharmacology study are interwoven with issues in Cell culture, Inflammation, Immunology, Glycoside and Structure–activity relationship. His research integrates issues of Indazole, Biological evaluation, Carbazole and Tricyclic in his study of Apoptosis.
His Cancer research study combines topics from a wide range of disciplines, such as Curcumin, Histone, Downregulation and upregulation and MAPK/ERK pathway. His Cell biology research is multidisciplinary, incorporating elements of Cyclin-dependent kinase 1 and Programmed cell death. In his research on the topic of Cytotoxicity, Stereochemistry is strongly related with Cell sorting.
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YC-1, a novel activator of platelet guanylate cyclase.
Feng-Nien Ko;Chin-Chung Wu;Sheng-Chu Kuo;Fang-Yu Lee.
6-Alkylamino- and 2,3-dihydro-3'-methoxy-2-phenyl-4-quinazolinones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
Mann-Jen Hour;Li-Jiau Huang;Sheng-Chu Kuo;Yi Xia.
Journal of Medicinal Chemistry (2000)
YC-1 inhibited human platelet aggregation through NO-independent activation of soluble guanylate cyclase.
Chin-Chung Wu;Feng-Nien Ko;Sheng-Chu Kuo;Fang-Yu Lee.
British Journal of Pharmacology (1995)
Studies on heterocyclic compounds. 6. Synthesis and analgesic and antiinflammatory activities of 3,4-dimethylpyrano[2,3-c]pyrazol-6-one derivatives.
S.-C. Kuo;L.-J. Huang;H. Nakamura.
Journal of Medicinal Chemistry (1984)
Antitumor Agents. 181. † Synthesis and Biological Evaluation of 6,7,2',3',4'-Substituted-1,2,3,4-tetrahydro-2-phenyl-4-quinolones as a New Class of Antimitotic Antitumor Agents
Yi Xia;Zheng Yu Yang;Peng Xia;Kenneth F. Bastow.
Journal of Medicinal Chemistry (1998)
Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: Identification as antimitotic agents interacting with tubulin
Sheng Chu Kuo;Hong Zin Lee;Jung Pin Juang;Yih Tyng Lin.
Journal of Medicinal Chemistry (1993)
Antitumor Agents. Part 204: Synthesis and Biological Evaluation of Substituted 2-Aryl Quinazolinones
Yi Xia;Zheng Yu Yang;Mann Jen Hour;Sheng Chu Kuo.
Bioorganic & Medicinal Chemistry Letters (2001)
Three new flavonoids and antiallergic, anti-inflammatory constituents from the heartwood of Dalbergia odorifera.
Shiuh-Chuan Chan;Yuan-Shiun Chang;Jih-Pyang Wang;Sheng-Chih Chen.
Planta Medica (1998)
Antiplatelet components in Panax ginseng.
Sheng-Chu Kuo;Che-Ming Teng;Jang-Chang Lee;Feng-Nien Ko.
Planta Medica (1990)
Antioxidant properties of butein isolated from Dalbergia odorifera
Zhi-Jiao Cheng;Sheng-Chu Kuo;Shiuh-Chuan Chan;Feng-Nien Ko.
Biochimica et Biophysica Acta (1998)
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