What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Organic chemistry
Stereochemistry, Pharmacology, Biochemistry, Cytotoxicity and Chemical synthesis are his primary areas of study.
The various areas that he examines in his Stereochemistry study include Biological activity, 1,4-Naphthoquinone, Structure–activity relationship and Mechanism of action.
His Pharmacology study incorporates themes from Superoxide, Nitric oxide, Immunology and Soluble guanylyl cyclase.
As a member of one scientific family, Sheng-Chu Kuo mostly works in the field of Biochemistry, focusing on Platelet and, on occasion, Phosphodiesterase.
His Cytotoxicity study results in a more complete grasp of In vitro.
His In vitro research is multidisciplinary, relying on both Cell culture and Aryl.
His most cited work include:
- YC-1, a novel activator of platelet guanylate cyclase. (432 citations)
- 6-Alkylamino- and 2,3-dihydro-3'-methoxy-2-phenyl-4-quinazolinones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization. (322 citations)
- YC-1 inhibited human platelet aggregation through NO-independent activation of soluble guanylate cyclase. (223 citations)
What are the main themes of his work throughout his whole career to date?
Sheng-Chu Kuo spends much of his time researching Stereochemistry, Pharmacology, Apoptosis, Cancer research and Biochemistry.
The Stereochemistry study combines topics in areas such as Lead compound, In vitro, Chemical synthesis and Cytotoxicity.
His work deals with themes such as Cell culture and Structure–activity relationship, which intersect with Cytotoxicity.
His biological study spans a wide range of topics, including Platelet and Mechanism of action.
The study incorporates disciplines such as Molecular biology, Cell growth and Cell biology in addition to Apoptosis.
His study in Cancer research is interdisciplinary in nature, drawing from both Cancer cell, Cancer, Internal medicine and Protein kinase B.
He most often published in these fields:
- Stereochemistry (21.91%)
- Pharmacology (19.65%)
- Apoptosis (18.89%)
What were the highlights of his more recent work (between 2012-2021)?
- Cancer research (14.86%)
- Pharmacology (19.65%)
- Apoptosis (18.89%)
In recent papers he was focusing on the following fields of study:
Sheng-Chu Kuo focuses on Cancer research, Pharmacology, Apoptosis, Cancer cell and Cell cycle.
His Cancer research research integrates issues from Cyclin-dependent kinase 1, Curcumin, Breast cancer and In vivo.
Sheng-Chu Kuo interconnects Cell culture, Mechanism of action, Potency, Cytotoxicity and Structure–activity relationship in the investigation of issues within Pharmacology.
Sheng-Chu Kuo has researched Apoptosis in several fields, including Indazole, Signal transduction, Cell biology and Cell growth.
His Cell biology research includes elements of Molecular biology and Programmed cell death.
His studies in Stereochemistry integrate themes in fields like Lead compound and Methylenedioxy.
Between 2012 and 2021, his most popular works were:
- Yuwen02f1 suppresses LPS-induced endotoxemia and adjuvant-induced arthritis primarily through blockade of ROS formation, NFkB and MAPK activation. (63 citations)
- EGFR Modulates DNA Synthesis and Repair through Tyr Phosphorylation of Histone H4 (53 citations)
- Curcumin suppresses doxorubicin-induced epithelial-mesenchymal transition via the inhibition of TGF-β and PI3K/AKT signaling pathways in triple-negative breast cancer cells. (51 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Gene
- Organic chemistry
His primary areas of study are Pharmacology, Apoptosis, Cancer research, Cell biology and Cancer cell.
The concepts of his Pharmacology study are interwoven with issues in Cell culture, Inflammation, Immunology, Glycoside and Structure–activity relationship.
His research integrates issues of Indazole, Biological evaluation, Carbazole and Tricyclic in his study of Apoptosis.
His Cancer research study combines topics from a wide range of disciplines, such as Curcumin, Histone, Downregulation and upregulation and MAPK/ERK pathway.
His Cell biology research is multidisciplinary, incorporating elements of Cyclin-dependent kinase 1 and Programmed cell death.
In his research on the topic of Cytotoxicity, Stereochemistry is strongly related with Cell sorting.
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