World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
82
Citations
23370
World Ranking
3102
National Ranking
29

Overview

What is he best known for?

The fields of study he is best known for:

  • Organic chemistry
  • Enzyme
  • Gene

His primary areas of investigation include Stereochemistry, Pharmacognosy, Biochemistry, Biological activity and Cytotoxicity. His work carried out in the field of Stereochemistry brings together such families of science as Annonaceae and Hep G2. The study incorporates disciplines such as Phenols, Glycoside, Bark and Alkaloid in addition to Pharmacognosy.

His research investigates the connection with Biological activity and areas like Anti-inflammatory which intersect with concerns in Elastase. Yang Chang Wu interconnects Cell culture, Apoptosis, Programmed cell death and Pharmacology in the investigation of issues within Cytotoxicity. His research in Apoptosis tackles topics such as Reactive oxygen species which are related to areas like Oxidative stress and Molecular biology.

His most cited work include:

  • Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells. (185 citations)
  • Cheritamine, A New N‐Fatty Acyl Tryptamine and Other Constituents from the Stems of Annona cherimola (138 citations)
  • Influenza A (H1N1) Antiviral and Cytotoxic Agents from Ferula assa-foetida (127 citations)

What are the main themes of his work throughout his whole career to date?

Yang Chang Wu mainly focuses on Stereochemistry, Biochemistry, Cytotoxicity, Pharmacognosy and Apoptosis. His Stereochemistry study incorporates themes from Biological activity, Cytotoxic T cell, Annonaceae and Coral. Yang Chang Wu combines subjects such as Two-dimensional nuclear magnetic resonance spectroscopy and Cancer cell lines with his study of Coral.

His studies in Cytotoxicity integrate themes in fields like Cell culture and Pharmacology. His biological study spans a wide range of topics, including Lactone and Alkaloid. His research integrates issues of Cancer cell, Molecular biology, Cancer research and Cell biology in his study of Apoptosis.

He most often published in these fields:

  • Stereochemistry (46.61%)
  • Biochemistry (19.19%)
  • Cytotoxicity (19.71%)

What were the highlights of his more recent work (between 2015-2021)?

  • Stereochemistry (46.61%)
  • Traditional medicine (9.79%)
  • Biochemistry (19.19%)

In recent papers he was focusing on the following fields of study:

Yang Chang Wu mostly deals with Stereochemistry, Traditional medicine, Biochemistry, Cytotoxicity and Anti-inflammatory. His Stereochemistry research is multidisciplinary, incorporating elements of Flueggea virosa, Gorgonian and Superoxide. Yang Chang Wu works mostly in the field of Traditional medicine, limiting it down to concerns involving Traditional Chinese medicine and, occasionally, Interleukin 17.

His Biochemistry research is mostly focused on the topic Metabolite. His Cytotoxicity study combines topics in areas such as Cytotoxic T cell and Pharmacology. Yang Chang Wu combines topics linked to Apoptosis with his work on Pharmacology.

Between 2015 and 2021, his most popular works were:

  • Anti-inflammatory Cerebrosides from Cultivated Cordyceps militaris (38 citations)
  • Soya-cerebroside reduces IL-1β-induced MMP-1 production in chondrocytes and inhibits cartilage degradation: implications for the treatment of osteoarthritis (30 citations)
  • Acetogenins from Annonaceae. (30 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Organic chemistry
  • Gene

The scientist’s investigation covers issues in Stereochemistry, Traditional medicine, Superoxide, Cell biology and Botany. Yang Chang Wu has included themes like Annonaceae, Sea anemone, Coral, Cytotoxicity and Cytotoxic T cell in his Stereochemistry study. His Superoxide study integrates concerns from other disciplines, such as Anti-inflammatory, Elastase, Zoanthamine and Stereoisomerism.

His Elastase study is associated with Biochemistry. He has researched Biochemistry in several fields, including Pharmacology and Shogaol. His Cell biology research is multidisciplinary, incorporating perspectives in Cell, Cell cycle, Apoptosis, Angiogenesis and Cerebroside.

Best Publications

  • Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells.

    Huei Mei Chen;Yang Chang Wu;Yi Chen Chia;Fang Rong Chang

  • Influenza A (H1N1) Antiviral and Cytotoxic Agents from Ferula assa-foetida

    Chia Lin Lee;Lien Chai Chiang;Li Hung Cheng;Chih Chuang Liaw

  • Cheritamine, A New N-Fatty Acyl Tryptamine and Other Constituents from the Stems of Annona cherimola

    Chung Yi Chen;Fang Rong Chang;Che Ming Teng;Yang Chang Wu

  • Recent research and development of Antrodia cinnamomea.

    Mei Chin Lu;Mei Chin Lu;Mohamed El-Shazly;Mohamed El-Shazly;Tung Ying Wu;Ying Chi Du

  • Identification of ent-16β,17-Dihydroxykauran-19-oic Acid as an Anti-HIV Principle and Isolation of the New Diterpenoids Annosquamosins A and B from Annona squamosa

    Yang Chang Wu;Yu Chun Hung;Fang Rong Chang;Mark Cosentino

  • Synthesis of chalcone derivatives as potential anti-diabetic agents

    Chi Ting Hsieh;Tusty Jiuan Hsieh;Mohamed El-Shazly;Mohamed El-Shazly;Da Wei Chuang

  • New cytotoxic monotetrahydrofuran annonaceous acetogenins from Annona muricata

    Chih Chuang Liaw;Fang Rong Chang;Chih Yuan Lin;Chi Jung Chou

  • Toona sinensis Roem tender leaf extract inhibits SARS coronavirus replication.

    Chung Jen Chen;Martin Michaelis;Hseng Kuang Hsu;Chin Chuan Tsai

  • The Constituents from the Stems of Annona cherimola

    Chung Yi Chen;Fang Rong Chang;Yang Chang Wu

  • Cytotoxic constituents of Polyalthia longifolia var. pendula.

    Chung Yi Chen;Fang Rong Chang;Yao Ching Shih;Tian Jye Hsieh

  • 6-Paradol and 6-Shogaol, the Pungent Compounds of Ginger, Promote Glucose Utilization in Adipocytes and Myotubes, and 6-Paradol Reduces Blood Glucose in High-Fat Diet-Fed Mice

    Chien Kei Wei;Yi Hong Tsai;Michal Korinek;Pei Hsuan Hung

  • Novel cytotoxic annonaceous acetogenins from Annona muricata.

    Fang-Rong Chang;Yang-Chang Wu

  • Aristolactams and dioxoaporphines from Fissistigma balansae and Fissistigma oldhamii

    Yi Chen Chia;Fang Rong Chang;Che Ming Teng;Yang Chang Wu

  • Molluscicidal Saponins from Sapindus mukorossi, Inhibitory Agents of Golden Apple Snails, Pomacea canaliculata

    Hui Chi Huang;Sin Chung Liao;Fang Rong Chang;Yao Haur Kuo

  • Annonacin, a mono-tetrahydrofuran acetogenin, arrests cancer cells at the G1 phase and causes cytotoxicity in a Bax- and caspase-3-related pathway.

    Shyng Shiou F. Yuan;Hsueh Ling Chang;Hsiao Wen Chen;Yao Tsung Yeh

  • Prevention of platelet glycoprotein IIb/IIIa activation by 3,4-methylenedioxy-β-nitrostyrene, a novel tyrosine kinase inhibitor

    Wei Ya Wang;Yang Chang Wu;Chin Chung Wu

  • Pristimerin induces caspase-dependent apoptosis in MDA-MB-231 cells via direct effects on mitochondria

    Chin Chung Wu;Mei Ling Chan;Wen Ying Chen;Ching Yi Tsai

  • Cytotoxic and anti-inflammatory cembranoids from the soft coral Lobophytum crassum.

    Chih Hua Chao;Zhi Hong Wen;Yang Chang Wu;Hsiao Chien Yeh

  • Automatic morphological subtyping reveals new roles of caspases in mitochondrial dynamics.

    Jyh Ying Peng;Jyh Ying Peng;Chung Chih Lin;Yen Jen Chen;Lung Sen Kao

  • Bioactive constitutents from the stems of Annona montana.

    Yang-Chang Wu;Gwo-Yuan Chang;Feng-Nien Ko;Che-Ming Teng

  • 4β-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest

    Ching Yu Yen;Chien Chih Chiu;Fang Rong Chang;Jeff Y. Chen

Frequent Co-Authors

Fang Rong Chang
Fang Rong Chang Kaohsiung Medical University
Tsong-Long Hwang
Tsong-Long Hwang Chang Gung University of Science and Technology
Jyh-Horng Sheu
Jyh-Horng Sheu National Sun Yat-sen University
Chin Chung Wu
Chin Chung Wu Kaohsiung Medical University
Kuo Hsiung Lee
Kuo Hsiung Lee University of Minnesota
Chang-Feng Dai
Chang-Feng Dai National Taiwan University
Che-Ming Teng
Che-Ming Teng National Taiwan University
Tian Shung Wu
Tian Shung Wu National Cheng Kung University
Fuu Jen Tsai
Fuu Jen Tsai China Medical University
Susan L. Morris-Natschke
Susan L. Morris-Natschke University of North Carolina at Chapel Hill

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