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Chemistry

D-Index
53
Citations
9988
World Ranking
13089
National Ranking
96

Overview

Ih-Sheng Chen is affiliated with Kaohsiung Medical University in Taiwan and has made contributions primarily in the domains of biochemistry, genetics, molecular biology, pharmacology, toxicology, and pharmaceutics. Their research spans several interconnected areas, with a focus on the biochemical properties and pharmacological effects of natural products and compounds derived from plants.

The scientist has published extensively on topics including:

  • Traditional and Medicinal Uses of Annonaceae
  • Phytochemistry and Bioactivity Studies
  • Plant-derived Lignans Synthesis and Bioactivity
  • Alkaloids: synthesis and pharmacology
  • Bioactive Natural Diterpenoids Research
  • Sesquiterpenes and Asteraceae Studies
  • Biological Activity of Diterpenoids and Biflavonoids

Their work is situated within molecular biology, pharmacology, and biochemistry, including cancer research and complementary and alternative medicine subfields. This diverse scientific focus is reflected in their publications across a number of academic journals, with repeated contributions in:

  • Molecules
  • Phytochemistry
  • International Journal of Molecular Sciences
  • PeerJ
  • Bioorganic Chemistry

Among recent publications are several studies that explore natural compounds and their pharmacological activity:

  • "Anti-HIV tigliane diterpenoids from Reutealis trisperma," 2020, Phytochemistry
  • "Anti-Inflammatory and Antibacterial Activity Constituents from the Stem of Cinnamomum validinerve," 2020, Molecules
  • "Antileukemic Natural Product Induced Both Apoptotic and Pyroptotic Programmed Cell Death and Differentiation Effect," 2021, International Journal of Molecular Sciences
  • "Cinnamtannin B1 attenuates rosacea-like signs via inhibition of pro-inflammatory cytokine production and down-regulation of the MAPK pathway," 2020, PeerJ
  • "Chemical Constituent of β-Glucuronidase Inhibitors from the Root of Neolitsea acuminatissima," 2020, Molecules

Ih-Sheng Chen has collaborated frequently with a core group of coauthors, which includes:

  • Hsun-Shuo Chang
  • Tsong-Long Hwang
  • Chi-Lung Yang
  • Ho-Cheng Wu
  • Chu-Hung Lin

The scientist's research contributions have helped to expand understanding of biochemical pathways and pharmacological effects of plant-derived compounds, particularly diterpenoids, lignans, and alkaloids, within the broader fields of molecular biology and pharmacology.

Best Publications

  • Anti-AIDS agents, 11. Betulinic acid and platanic acid as anti-HIV principles from Syzigium claviflorum, and the anti-HIV activity of structurally related triterpenoids.

    T. Fujioka;Y. Kashiwada;R. E. Kilkuskie;L. M. Cosentino

  • Coumarins and antiplatelet aggregation constituents from Formosan Peucedanum japonicum.

    Ih-Sheng Chen;Chin-Teng Chang;Wine-Show Sheen;Che-Ming Teng

  • Chemical and bioactive constituents from Zanthoxylum simulans

    Ih Sheng Chen;Shwu Jen Wu;Ian Lih Tsai;Tian Shung Wu

  • Coumarins and anti-platelet aggregation constituents from Zanthoxylum schinifolium.

    Ih-Sheng Chen;Yuh-Chwen Lin;Ian-Lih Tsai;Che-Ming Teng

  • Pyranoquinoline alkaloids from Zanthoxylum simulans

    Ih Sheng Chen;Inn Wha Tsai;Che Ming Teng;Jih Jung Chen

  • New cytotoxic cyclobutanoid amides, a new furanoid lignan and anti-platelet aggregation constituents from Piper arborescens.

    Ian Lih Tsai;Fan Pin Lee;Chin Chung Wu;Chang Yih Duh

  • A novel dimeric coumarin analog and antimycobacterial constituents from Fatoua pilosa.

    Chun-Ching Chiang;Ming-Jen Cheng;Chien-Fang Peng;Hung-Yi Huang

  • Chemical and anti-platelet constituents from Formosan Zanthoxylum simulans.

    Ya-Ping Yang;Ming-Jen Cheng;Che-Ming Teng;Ya-Ling Chang

  • (–)–Epigallocatechin Gallate Inhibition of Osteoclastic Differentiation via NF-Κb

    Ru-Wei Lin;Chung-Hwan Chen;Yan-Hsiung Wang;Mei-Ling Ho

  • Two new sesquiterpenoids and anti-HIV principles from the root bark of Zanthoxylum ailanthoides.

    Ming Jen Cheng;Kuo Hsiung Lee;Ian Lih Tsai;Ih Sheng Chen

  • New phenylpropenoids, bis(1-phenylethyl)phenols, bisquinolinone alkaloid, and anti-inflammatory constituents from Zanthoxylum integrifoliolum.

    Jih Jung Chen;Po Hou Chen;Chang Hui Liao;Shi Yu Huang

  • Coumarins and anti-HBV constituents from Zanthoxylum schinifolium

    Chin-Teng Chang;Shin-Lian Doong;Ian-Lih Tsai;Ih-Sheng Chen

  • Coumarins and antiplatelet constituents from the root bark of Zanthoxylum schinifolium

    Ian-Lih Tsai;Wei-Yu Lin;Che-Ming Teng;Tsutomu Ishikawa

  • Anti-platelet aggregation and chemical constituents from the rhizome of Gynura japonica.

    Wei-Yu Lin;Yueh-Hsiung Kuo;Ya-Ling Chang;Che-Ming Teng

  • New indolopyridoquinazoline, benzo[c]phenanthridines and cytotoxic constituents from Zanthoxylum integrifoliolum.

    Jih-Jung Chen;Hui-Yu Fang;Chang-Yih Duh;Ih-Sheng Chen

  • Chemical and cytotoxic constituents from Peperomia sui.

    Ming-Jen Cheng;Shoiw-Ju Lee;Ying-Ying Chang;Szu-Huei Wu

  • Maleimide and maleic anhydride derivatives from the mycelia of Antrodia cinnamomea and their nitric oxide inhibitory activities in macrophages.

    Ming-Der Wu;Ming-Jen Cheng;Bor-Cheh Wang;Yi-Jen Yech

  • Anti-platelet aggregation alkaloids and lignans from Hernandia nymphaeifolia

    Jih Jung Chen;Ya Ling Chang;Che Ming Teng;Ih Sheng Chen

  • New benzenoids and anti-inflammatory constituents from Zanthoxylum nitidum

    Jih Jung Chen;Yu Hsien Lin;Shiow Hwa Day;Tsong Long Hwang

  • Costunolide causes mitotic arrest and enhances radiosensitivity in human hepatocellular carcinoma cells

    Chia-Yuan Liu;Hsun-Shuo Chang;Ih-Sheng Chen;Chih-Jen Chen

  • Benzophenone derivatives from the fruits of Garcinia multiflora and their anti-inflammatory activity.

    Jih-Jung Chen;Chia-Wei Ting;Tsong-Long Hwang;Ih-Sheng Chen

Frequent Co-Authors

Tsutomu Ishikawa
Tsutomu Ishikawa Chiba University
Che-Ming Teng
Che-Ming Teng National Taiwan University
Chang-Yih Duh
Chang-Yih Duh National Sun Yat-sen University
Tsong-Long Hwang
Tsong-Long Hwang Chang Gung University of Science and Technology
Yueh-Hsiung Kuo
Yueh-Hsiung Kuo China Medical University
Kuo Hsiung Lee
Kuo Hsiung Lee University of Minnesota
Yoshiyasu Fukuyama
Yoshiyasu Fukuyama Tokushima Bunri University
Yoshiki Kashiwada
Yoshiki Kashiwada University of Tokushima
Tian Shung Wu
Tian Shung Wu National Cheng Kung University
Tur-Fu Huang
Tur-Fu Huang National Taiwan University

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