Mattia Bonsignori mainly focuses on Virology, Antibody, Epitope, Immunology and Monoclonal antibody. His work on Virus as part of general Virology study is frequently connected to Plasma protein binding, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His Antibody study integrates concerns from other disciplines, such as Lineage, Peptide sequence and Immune system.
His work on Vaccine efficacy as part of general Immune system study is frequently linked to AIDSVAX, therefore connecting diverse disciplines of science. His Epitope study frequently involves adjacent topics like Binding site. Mattia Bonsignori interconnects Phylogenetics and Site specificity in the investigation of issues within Immunology.
His primary areas of investigation include Antibody, Virology, Epitope, Immunology and Immune system. His studies deal with areas such as Antigen and Vaccination as well as Antibody. His biological study spans a wide range of topics, including Lineage, Immunogen and Glycan.
His Epitope research includes elements of Glycoprotein, Antibody-dependent cell-mediated cytotoxicity and Binding site. His work in the fields of Memory B cell, Vaccine efficacy and Autoantibody overlaps with other areas such as Context. His Monoclonal antibody research is multidisciplinary, incorporating elements of Peptide sequence, Malaria and Immunoglobulin A.
His main research concerns Antibody, Virology, Epitope, Vaccination and Immune system. His Antibody study introduces a deeper knowledge of Immunology. His Virology study frequently draws connections to other fields, such as Glycan.
His studies in Epitope integrate themes in fields like Neutralization, Vaccine trial, Immunogen and Binding site. Mattia Bonsignori combines subjects such as Germinal center and Blocking antibody with his study of Immune system. The Vaccine efficacy study combines topics in areas such as Somatic hypermutation, Monoclonal antibody and Memory B cell.
Mattia Bonsignori mainly investigates Immunology, Antibody, Antibody titer, Circumsporozoite protein and Antigen. The various areas that Mattia Bonsignori examines in his Immunology study include Phenotype and Germline mutation. His work deals with themes such as Epitope, Plasmodium falciparum, Immune system and Vaccination, which intersect with Antibody titer.
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Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
Jason S. McLellan;Marie Pancera;Chris Carrico;Jason Gorman.
Analysis of a Clonal Lineage of HIV-1 Envelope V2/V3 Conformational Epitope-Specific Broadly Neutralizing Antibodies and Their Inferred Unmutated Common Ancestors
Mattia Bonsignori;Kwan Ki Hwang;Xi Chen;Chun Yen Tsao.
Journal of Virology (2011)
Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies from an HIV-1 Vaccine Efficacy Trial Target Multiple Epitopes and Preferentially Use the VH1 Gene Family
Mattia Bonsignori;Justin Pollara;M. Anthony Moody;Michael D. Alpert.
Journal of Virology (2012)
Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2
Hua Xin Liao;Mattia Bonsignori;S. Munir Alam;Jason S. McLellan.
Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG
Georgia D. Tomaras;Guido Ferrari;Xiaoying Shen;S. Munir Alam.
Proceedings of the National Academy of Sciences of the United States of America (2013)
Magnitude and Breadth of the Neutralizing Antibody Response in the RV144 and Vax003 HIV-1 Vaccine Efficacy Trials
David C. Montefiori;Chitraporn Karnasuta;Ying Huang;Hasan Ahmed.
The Journal of Infectious Diseases (2012)
Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Tongqing Zhou;Jiang Zhu;Xueling Wu;Stephanie Moquin.
Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies
Feng Gao;Mattia Bonsignori;Hua Xin Liao;Amit Kumar.
Interaction with Cellular CD4 Exposes HIV-1 Envelope Epitopes Targeted by Antibody-Dependent Cell-Mediated Cytotoxicity
Maxime Veillette;Anik Désormeaux;Halima Medjahed;Nour-Elhouda Gharsallah.
Journal of Virology (2014)
Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody
Mattia Bonsignori;Tongqing Zhou;Zizhang Sheng;Lei Chen.
Profile was last updated on December 6th, 2021.
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