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Nobuharu Fujii

Nobuharu Fujii

Overview

Nobuharu Fujii is affiliated with Tohoku University in Japan, contributing to research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields including Molecular Biology, Physiology, Biomedical Engineering, Rehabilitation, and Cardiology and Cardiovascular Medicine.

The research focus covers a range of topics with emphasis on Muscle Physiology and Disorders, Adipose Tissue and Metabolism, Exercise and Physiological Responses, Advanced Sensor and Energy Harvesting Materials, Cardiovascular Effects of Exercise, Mitochondrial Function and Pathology, and Cancer, Hypoxia, and Metabolism.

Recent publications illustrate this breadth of study with papers such as:

  • "Excess Glucose Impedes the Proliferation of Skeletal Muscle Satellite Cells Under Adherent Culture Conditions" (2021) in Frontiers in Cell and Developmental Biology
  • "Trans-omic Analysis Reveals ROS-Dependent Pentose Phosphate Pathway Activation after High-Frequency Electrical Stimulation in C2C12 Myotubes" (2020) in iScience
  • "Effect of antioxidant supplementation on skeletal muscle and metabolic profile in aging mice" (2021) in Food & Function
  • "Single-Cell Information Analysis Reveals That Skeletal Muscles Incorporate Cell-to-Cell Variability as Information Not Noise" (2020) in Cell Reports
  • "PDGF-B secreted from skeletal muscle enhances myoblast proliferation and myotube maturation via activation of the PDGFR signaling cascade" (2022) in Biochemical and Biophysical Research Communications

The scientist collaborates frequently with peers such as Yasuko Manabe, Yasuro Furuichi, Hiroki Hamaguchi, Yoshitaka Mita, and Naoko Goto-Inoue, reflecting a network of sustained academic partnerships.

Publication venues where Nobuharu Fujii's work appears often include:

  • Scientific Reports
  • Frontiers in Cell and Developmental Biology
  • The Journal of Physical Fitness and Sports Medicine
  • Molecular Biology Reports
  • Biochemical and Biophysical Research Communications

Best Publications

  • Role of AMP-activated protein kinase in mechanism of metformin action

    Gaochao Zhou;Robert Myers;Ying Li;Yuli Chen

  • AMP-Activated Protein Kinase (AMPK) Is Activated in Muscle of Subjects With Type 2 Diabetes During Exercise

    Nicolas Musi;Nobuharu Fujii;Michael F. Hirshman;Ingvar Ekberg

  • Exercise induces isoform-specific increase in 5'AMP-activated protein kinase activity in human skeletal muscle.

    Nobuharu Fujii;Tatsuya Hayashi;Michael F. Hirshman;Jeremy T. Smith

  • Distinct Signals Regulate AS160 Phosphorylation in Response to Insulin, AICAR, and Contraction in Mouse Skeletal Muscle

    Henning F. Kramer;Carol A. Witczak;Nobuharu Fujii;Niels Jessen

  • Skeletal Muscle Adaptation to Exercise Training: AMP-Activated Protein Kinase Mediates Muscle Fiber Type Shift

    Katja S.C. Röckl;Michael F. Hirshman;Josef Brandauer;Nobuharu Fujii

  • AS160 regulates insulin- and contraction-stimulated glucose uptake in mouse skeletal muscle.

    Henning F. Kramer;Carol A. Witczak;Eric B. Taylor;Nobuharu Fujii

  • AMP-activated protein kinase activity and glucose uptake in rat skeletal muscle

    Nicolas Musi;Tatsuya Hayashi;Nobuharu Fujii;Michael F. Hirshman

  • Discovery of TBC1D1 as an Insulin-, AICAR-, and Contraction-stimulated Signaling Nexus in Mouse Skeletal Muscle

    Eric B. Taylor;Ding An;Ding An;Henning F. Kramer;Henning F. Kramer;Haiyan Yu;Haiyan Yu

  • AMP-activated protein kinase and the regulation of glucose transport.

    Nobuharu Fujii;Niels Jessen;Laurie J. Goodyear

  • Efficient and Reproducible Myogenic Differentiation from Human iPS Cells: Prospects for Modeling Miyoshi Myopathy In Vitro

    Akihito Tanaka;Akihito Tanaka;Knut Woltjen;Katsuya Miyake;Akitsu Hotta

  • Glucose Metabolism and Energy Homeostasis in Mouse Hearts Overexpressing Dominant Negative α2 Subunit of AMP-activated Protein Kinase

    Yanqiu Xing;Nicolas Musi;Nobuharu Fujii;Liqun Zou

  • Root hydrotropism is controlled via a cortex-specific growth mechanism

    Daniela Dietrich;Lei Pang;Akie Kobayashi;John A. Fozard

  • AMP-activated Protein Kinase α2 Activity Is Not Essential for Contraction- and Hyperosmolarity-induced Glucose Transport in Skeletal Muscle

    Nobuharu Fujii;Michael F. Hirshman;Erin M. Kane;Richard C. Ho

  • Skeletal Muscle-Selective Knockout of LKB1 Increases Insulin Sensitivity, Improves Glucose Homeostasis, and Decreases TRB3

    Ho Jin Koh;David E. Arnolds;Nobuharu Fujii;Thien T. Tran

  • A gene essential for hydrotropism in roots.

    Akie Kobayashi;Akiko Takahashi;Yoko Kakimoto;Yutaka Miyazawa

  • Oxidative stress stimulates skeletal muscle glucose uptake through a phosphatidylinositol 3-kinase-dependent pathway.

    Yasuki Higaki;Toshio Mikami;Nobuharu Fujii;Michael F. Hirshman

  • Ca2+/Calmodulin-Dependent Protein Kinase Kinase-α Regulates Skeletal Muscle Glucose Uptake Independent of AMP-Activated Protein Kinase and Akt Activation

    Carol A. Witczak;Nobuharu Fujii;Michael F. Hirshman;Laurie J. Goodyear

  • The M Locus and Ethylene-Controlled Sex Determination in Andromonoecious Cucumber Plants

    Seiji Yamasaki;Nobuharu Fujii;Seiji Matsuura;Hidemasa Mizusawa

  • The Ethylene-Regulated Expression of CS-ETR2 and CS-ERS Genes in Cucumber Plants and Their Possible Involvement with Sex Expression in Flowers

    Seiji Yamasaki;Nobuharu Fujii;Hideyuki Takahashi

  • Effect of AICAR Treatment on Glycogen Metabolism in Skeletal Muscle

    William G. Aschenbach;Michael F. Hirshman;Nobuharu Fujii;Kei Sakamoto

Frequent Co-Authors

Hideyuki Takahashi
Hideyuki Takahashi Chiba University
Kazuhiko Nishitani
Kazuhiko Nishitani Kanagawa University
Shigeru Iida
Shigeru Iida University of Shizuoka
Kazuyoshi Takeda
Kazuyoshi Takeda Okayama University
Tobias I. Baskin
Tobias I. Baskin University of Massachusetts Amherst
Jeremy A. Roberts
Jeremy A. Roberts Plymouth University
Hidehiro Fukaki
Hidehiro Fukaki Kobe University
Kouki Hikosaka
Kouki Hikosaka Tohoku University
Takayuki Hoson
Takayuki Hoson Osaka Metropolitan University
Yoshinori Kanayama
Yoshinori Kanayama Tohoku University

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