Kazuyoshi Takeda

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Best Publications

• Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells.

  Kazuyoshi Takeda;Yoshihiro Hayakawa;Mark J. Smyth;Nobuhiko Kayagaki

  973
  Citations

• The Natural Killer T (NKT) Cell Ligand α-Galactosylceramide Demonstrates Its Immunopotentiating Effect by Inducing Interleukin (IL)-12 Production by Dendritic Cells and IL-12 Receptor Expression on NKT Cells

  Hidemitsu Kitamura;Kenji Iwakabe;Takashi Yahata;Shin-ichiro Nishimura

  945
  Citations

• Improved efficacy of neoadjuvant compared to adjuvant immunotherapy to eradicate metastatic disease

  Jing Liu;Jing Liu;Stephen J. Blake;Michelle C.R. Yong;Heidi Harjunpää;Heidi Harjunpää

  840
  Citations

• Increased Susceptibility to Tumor Initiation and Metastasis in TNF-Related Apoptosis-Inducing Ligand-Deficient Mice

  Erika Cretney;Kazuyoshi Takeda;Hideo Yagita;Moira Glaccum

  787
  Citations

• An Aluminum-Activated Citrate Transporter in Barley

  Jun Furukawa;Naoki Yamaji;Hua Wang;Namiki Mitani

  645
  Citations

• Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail) Contributes to Interferon γ–Dependent Natural Killer Cell Protection from Tumor Metastasis

  Mark J. Smyth;Erika Cretney;Kazuyoshi Takeda;Robert H. Wiltrout

  637
  Citations

• Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells

  Yulong Gao;Yulong Gao;Fernando Souza-Fonseca-Guimaraes;Fernando Souza-Fonseca-Guimaraes;Fernando Souza-Fonseca-Guimaraes;Tobias Bald;Susanna S Ng;Susanna S Ng

  632
  Citations

• Critical Role for Tumor Necrosis Factor–related Apoptosis-inducing Ligand in Immune Surveillance Against Tumor Development

  Kazuyoshi Takeda;Mark J. Smyth;Erika Cretney;Yoshihiro Hayakawa

  626
  Citations

• Nature's TRAIL: On a path to cancer immunotherapy

  Mark J Smyth;Kazuyoshi Takeda;Yoshihiro Hayakawa;Jacques J Peschon

  474
  Citations

• The liver as a crucial organ in the first line of host defense: the roles of Kupffer cells, natural killer (NK) cells and NK1.1 Ag+ T cells in T helper 1 immune responses.

  Shuhji Seki;Yoshiko Habu;Toshihiko Kawamura;Kazuyoshi Takeda

  452
  Citations

• Barley grain with adhering hulls is controlled by an ERF family transcription factor gene regulating a lipid biosynthesis pathway.

  Shin Taketa;Satoko Amano;Yasuhiro Tsujino;Tomohiko Sato

  443
  Citations

• Co-inhibition of CD73 and A2AR Adenosine Signaling Improves Anti-tumor Immune Responses

  Arabella Young;Arabella Young;Shin Foong Ngiow;Shin Foong Ngiow;Deborah S. Barkauskas;Erin Sult

  390
  Citations

• Eradication of established tumors in mice by a combination antibody-based therapy.

  Tomoyasu Uno;Kazuyoshi Takeda;Kazuyoshi Takeda;Yuko Kojima;Hirohisa Yoshizawa

  379
  Citations

• Antiviral response by natural killer cells through TRAIL gene induction by IFN–α/β

  Kojiro Sato;Shigeaki Hida;Hiroshi Takayanagi;Taeko Yokochi

  370
  Citations

• Requirement for natural killer T (NKT) cells in the induction of allograft tolerance.

  Ken-ichiro Seino;Katashi Fukao;Kenzo Muramoto;Kazuhiko Yanagisawa

  351
  Citations

• The development of autoimmunity in C57BL/6 lpr mice correlates with the disappearance of natural killer type 1-positive cells: evidence for their suppressive action on bone marrow stem cell proliferation, B cell immunoglobulin secretion, and autoimmune symptoms.

  Kazuyoshi Takeda;Gunther Dennert

  325
  Citations

• Plasmodium berghei Infection in Mice Induces Liver Injury by an IL-12- and Toll-Like Receptor/Myeloid Differentiation Factor 88-Dependent Mechanism

  Keishi Adachi;Hiroko Tsutsui;Shin-Ichiro Kashiwamura;Ekihiro Seki

  320
  Citations

• TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver.

  Kazuyoshi Takeda;Erika Cretney;Erika Cretney;Erika Cretney;Yoshihiro Hayakawa;Yoshihiro Hayakawa;Yoshihiro Hayakawa;Tsuyoshi Ota;Tsuyoshi Ota;Tsuyoshi Ota

  318
  Citations

• A semidwarf phenotype of barley uzu results from a nucleotide substitution in the gene encoding a putative brassinosteroid receptor.

  Makiko Chono;Ichiro Honda;Haruko Zeniya;Koichi Yoneyama

  310
  Citations

• Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy

  Kazuyoshi Takeda;Noriko Yamaguchi;Hisaya Akiba;Yuko Kojima

  293
  Citations