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Immunology

D-Index
45
Citations
6036
World Ranking
4730
National Ranking
2131

Overview

Paul J. Cote is affiliated with Georgetown University Medical Center in the United States. Their research primarily focuses on medical fields, with an emphasis on epidemiology and hepatology.

The main topics explored in their work include:

  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Liver Disease Diagnosis and Treatment

Cote's publication record includes contributions to the journal Hepatology. Among their recent work is a 2020 paper titled "Toll-Like Receptor 8 Agonist GS-9688 Induces Sustained Efficacy in the Woodchuck Model of Chronic Hepatitis B", published in Hepatology.

Frequent collaborators include:

  • Stéphane Daffis
  • Scott Balsitis
  • Jason Chamberlain
  • Jim Zheng
  • Rex Santos

The scientist's work is situated at the intersection of chronic viral hepatitis research and liver disease treatment approaches, contributing to a deeper understanding of viral mechanisms and potential therapeutic targets in hepatitis B and C.

Best Publications

  • The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks

    Hong-Shu Chen;S. Kaneko;R. Girones;R. W. Anderson

  • Antiviral l-Nucleosides Specific for Hepatitis B Virus Infection

    Martin L. Bryant;Edward G. Bridges;Laurent Placidi;Abdesslem Faraj

  • The woodchuck as an animal model for pathogenesis and therapy of chronic hepatitis B virus infection.

    Stephan Menne;Paul J Cote

  • Sustained efficacy and seroconversion with the Toll-like receptor 7 agonist GS-9620 in the Woodchuck model of chronic hepatitis B

    Stephan Menne;Daniel B. Tumas;Katherine H. Liu;Linta Thampi

  • Transmission of the hepatitis B virus-associated delta agent to the eastern woodchuck.

    Antonio Ponzetto;Paul J. Cote;Hans Popper;Bill H. Hoyer

  • Hepatocellular carcinoma in woodchuck hepatitis virus-infected woodchucks: presence of viral DNA in tumor tissue from chronic carriers and animals serologically recovered from acute infections.

    Brent E. Korba;Brent E. Korba;Frances V. Wells;Betty Baldwin;Paul J. Cote

  • Antiviral activity of clevudine [L‐FMAU, (1‐(2‐fluoro‐5‐methyl‐β, L‐arabinofuranosyl) uracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks (Marmota monax)

    Simon F. Peek;Paul J. Cote;James R. Jacob;Ilia A. Toshkov

  • Hepatocellular carcinoma in the woodchuck model of hepatitis B virus infection

    Bud C. Tennant;Ilia A. Toshkov;Simon F. Peek;James R. Jacob

  • Effects of age and viral determinants on chronicity as an outcome of experimental woodchuck hepatitis virus infection

    Paul J. Cote;Brent E. Korba;Roger H. Miller;James R. Jacob

  • Licensed recombinant hepatitis B vaccines protect chimpanzees against infection with the prototype surface gene mutant of hepatitis B virus.

    Norio Ogata;Paul J. Cote;Alessandro R. Zanetti;Roger H. Miller

  • Treatment of chronic woodchuck hepatitis virus infection in the eastern woodchuck (marmota monax) with nucleoside analogues is predictive of therapy for chronic hepatitis B virus infection in humans

    Brent E. Korba;Paul Cote;William Hornbuckle;Bud C. Tennant

  • Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection.

    Bud C. Tennant;Betty H. Baldwin;Lou Ann Graham;Mary A. Ascenzi

  • Deficiencies in the acute-phase cell-mediated immune response to viral antigens are associated with development of chronic woodchuck hepatitis virus infection following neonatal inoculation

    Stephan Menne;Carol A. Roneker;Michael Roggendorf;John L. Gerin

  • Immunization with Surface Antigen Vaccine Alone and after Treatment with 1-(2-Fluoro-5-Methyl-β-l-Arabinofuranosyl)-Uracil (l-FMAU) Breaks Humoral and Cell-Mediated Immune Tolerance in Chronic Woodchuck Hepatitis Virus Infection

    Stephan Menne;Carol A. Roneker;Brent E. Korba;John L. Gerin

  • Analysis of the respiratory syncytial virus fusion protein using monoclonal and polyclonal antibodies.

    Edward E. Walsh;Paul J. Cote;Bruce F. Fernie;Jacob J. Schlesinger

  • Preclinical investigation of L-FMAU as an anti-hepatitis B virus agent.

    C K Chu;F D Boudinot;S F Peek;J H Hong

  • Pathogenesis of experimental neonatal woodchuck hepatitis virus infection: chronicity as an outcome of infection is associated with a diminished acute hepatitis that is temporally deficient for the expression of interferon gamma and tumor necrosis factor-alpha messenger RNAs.

    Ikuo Nakamura;James T. Nupp;Matthew Cowlen;William C. Hall

  • Core antigen and antibody in woodchucks after infection with woodchuck hepatitis virus.

    A Ponzetto;P J Cote;E C Ford;R H Purcell

  • Natural history of woodchuck hepatitis virus infections during the course of experimental viral infection: molecular virologic features of the liver and lymphoid tissues.

    B E Korba;P J Cote;F V Wells;B Baldwin

  • Mitogen-induced replication of woodchuck hepatitis virus in cultured peripheral blood lymphocytes.

    Brent E. Korba;Paul J. Cote;John L. Gerin

Frequent Co-Authors

Bud C. Tennant
Bud C. Tennant Cornell University
John L. Gerin
John L. Gerin Georgetown University Medical Center
Brent E. Korba
Brent E. Korba Georgetown University
Robert H. Purcell
Robert H. Purcell National Institute of Allergy and Infectious Diseases
Raymond F. Schinazi
Raymond F. Schinazi Emory University
Ronald E. Engle
Ronald E. Engle National Institute of Allergy and Infectious Diseases
Chung K. Chu
Chung K. Chu University of Georgia
Rosina Girones
Rosina Girones University of Barcelona
Dieter Glebe
Dieter Glebe University of Giessen
Hollis N. Erb
Hollis N. Erb Cornell University

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