D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 44 Citations 13,985 111 World Ranking 16005 National Ranking 258

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • DNA
  • Amino acid

George Panayotou mainly investigates Biochemistry, Molecular biology, Kinase, Receptor tyrosine kinase and SH2 domain. His Molecular biology research incorporates themes from Receptor and DNA. His Kinase research entails a greater understanding of Cell biology.

George Panayotou combines subjects such as Growth factor receptor, Proto-oncogene tyrosine-protein kinase Src and Platelet-derived growth factor receptor with his study of Receptor tyrosine kinase. His study explores the link between SH2 domain and topics such as G alpha subunit that cross with problems in Insulin-like growth factor 1 receptor. The Binding site study combines topics in areas such as Protein structure and Epidermal growth factor.

His most cited work include:

  • A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family (874 citations)
  • Phosphoinositide 3-kinases: a conserved family of signal transducers. (865 citations)
  • Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase. (629 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Biochemistry, Cell biology, Molecular biology, Kinase and SH2 domain. His research related to Binding site, Phosphatidylinositol, Receptor tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src and Kinase activity might be considered part of Biochemistry. George Panayotou has included themes like Receptor and Epidermal growth factor in his Cell biology study.

His Molecular biology study combines topics in areas such as Epitope, Antibody, DNA glycosylase and Enzyme. His study looks at the relationship between Kinase and fields such as Phosphorylation, as well as how they intersect with chemical problems. His work in SH2 domain tackles topics such as G alpha subunit which are related to areas like Protein structure.

He most often published in these fields:

  • Biochemistry (37.04%)
  • Cell biology (29.63%)
  • Molecular biology (21.30%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cell biology (29.63%)
  • Cancer research (7.41%)
  • Pathology (3.70%)

In recent papers he was focusing on the following fields of study:

George Panayotou spends much of his time researching Cell biology, Cancer research, Pathology, Neuroscience and Kinase. His biological study spans a wide range of topics, including RNA splicing and Group II intron. His Cancer research study which covers Experimental autoimmune encephalomyelitis that intersects with Extracellular and Encephalomyelitis.

His Pathology research focuses on subjects like Ataxia, which are linked to Antibody, Receptor, Autoantibody and Immunoglobulin G. His Kinase research incorporates elements of mTORC1, High-throughput screening and Neuroprotection. His studies deal with areas such as Molecular biology and Colocalization as well as Cytoplasm.

Between 2016 and 2021, his most popular works were:

  • Novel insights into SLC25A46-related pathologies in a genetic mouse model. (20 citations)
  • New Insights for RANKL as a Proinflammatory Modulator in Modeled Inflammatory Arthritis. (10 citations)
  • Drosophila Tau Negatively Regulates Translation and Olfactory Long-Term Memory, But Facilitates Footshock Habituation and Cytoskeletal Homeostasis. (6 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • DNA
  • Amino acid

His primary areas of study are Cell biology, Intron, Group II intron, Chloroplast and RNA splicing. His Cell biology research is multidisciplinary, incorporating elements of Ex vivo, In vitro, Biodistribution, Cytotoxicity and Liposome. His Intron research spans across into fields like Spliceosome and Post-transcriptional regulation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Phosphoinositide 3-kinases: a conserved family of signal transducers.

Bart Vanhaesebroeck;Sally J. Leevers;George Panayotou;Michael D. Waterfield.
Trends in Biochemical Sciences (1997)

1330 Citations

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

Carola Ponzetto;Alberto Bardelli;Alberto Bardelli;Zhu Zhen;Flavio Maina.
Cell (1994)

1180 Citations

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase.

Masayuki Otsu;Ian Hiles;Ivan Gout;Michael J. Fry.
Cell (1991)

913 Citations

Phosphatidylinositol 3-kinase : structure and expression of the 110 kd catalytic subunit

Ian D. Hiles;Masayuki Otsu;Stefano Volinia;Michael J. Fry.
Cell (1992)

905 Citations

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction.

M P Wymann;G Bulgarelli-Leva;M J Zvelebil;L Pirola.
Molecular and Cellular Biology (1996)

869 Citations

Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase.

K Salim;M J Bottomley;E Querfurth;M J Zvelebil.
The EMBO Journal (1996)

726 Citations

The GTPase dynamin binds to and is activated by a subset of SH3 domains.

Ivan Gout;Ritu Dhand;Ian D. Hiles;Michael J. Fry.
Cell (1993)

690 Citations

PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.

R Dhand;I Hiles;G Panayotou;S Roche.
The EMBO Journal (1994)

602 Citations

PI 3-kinase: structural and functional analysis of intersubunit interactions.

Ritu Dhand;K. Hara;I. Hiles;B. Bax.
The EMBO Journal (1994)

435 Citations

Domains of laminin with growth-factor activity

George Panayotou;Peter End;Monique Aumailley;Rupert Timpl.
Cell (1989)

394 Citations

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