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Immunology

D-Index
57
Citations
13462
World Ranking
3597
National Ranking
1666

Overview

Ronald E. Engle is affiliated with the National Institute of Allergy and Infectious Diseases in the United States. Their research primarily spans the field of Medicine, with a significant focus on subfields including Hepatology, Epidemiology, Pharmacology, Molecular Biology, and Plant Science.

The scientist's work covers several key topics in medical research. These include:

  • Hepatitis Viruses Studies and Epidemiology
  • Hepatitis B Virus Studies
  • Hepatitis C Virus Research
  • Liver Disease and Transplantation
  • Drug-Induced Hepatotoxicity and Protection
  • Studies on Chitinases and Chitosanases
  • Phytase and its Applications

Ronald E. Engle has contributed to a variety of scientific publications, with recent papers reflecting their research interests in viral hepatitis and liver diseases. Selected recent publications include:

  • "Chitinase 3-like 1 is a profibrogenic factor overexpressed in the aging liver and in patients with liver cirrhosis," 2021, Proceedings of the National Academy of Sciences
  • "Molecular Signature and Immune Landscape of HCV-Associated Hepatocellular Carcinoma (HCC): Differences and Similarities with HBV-HCC," 2021, Journal of Hepatocellular Carcinoma
  • "Distinct Cytokine Profiles Correlate with Disease Severity and Outcome in Longitudinal Studies of Acute Hepatitis B Virus and Hepatitis D Virus Infection in Chimpanzees," 2020, mBio
  • "Incidence of Hepatitis E Infection in American Patients With Suspected Drug-Induced Liver Injury Is Low and Declining: The DILIN Prospective Study," 2022, The American Journal of Gastroenterology
  • "Role of Hepatitis E Virus Infection in North American Patients With Severe Acute Liver Injury," 2020, Clinical and Translational Gastroenterology

The frequent publication venues for Ronald E. Engle's work include:

  • Proceedings of the National Academy of Sciences
  • Journal of Hepatocellular Carcinoma
  • mBio
  • The American Journal of Gastroenterology
  • PLoS Pathogens

Key collaborators in their research include Patrizia Farci, Hanh Nguyen, David E. Kleiner, Robert H. Purcell, and Norihisa Nishimura, reflecting interdisciplinary and collaborative efforts within their fields of study.

Best Publications

  • Lack of protective immunity against reinfection with hepatitis C virus

    Patrizia Farci;Harvey J. Alter;Sugantha Govindarajan;Doris C. Wong

  • Prevalence of Antibodies to Hepatitis E Virus in Veterinarians Working with Swine and in Normal Blood Donors in the United States and Other Countries

    X. J. Meng;B. Wiseman;F. Elvinger;D. K. Guenette

  • Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization.

    Patrizia Farci;Harvey J. Alter;Doris C. Wong;Roger H. Miller

  • A virus discovery method incorporating DNase treatment and its application to the identification of two bovine parvovirus species.

    Tobias Allander;Suzanne U. Emerson;Ronald E. Engle;Robert H. Purcell

  • Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention

    Ana P. Goncalvez;Ronald E. Engle;Marisa St. Claire;Robert H. Purcell

  • In vitro assay for neutralizing antibody to hepatitis C virus: evidence for broadly conserved neutralization epitopes.

    Birke Bartosch;Jens Bukh;Jean-Christophe Meunier;Christelle Granier

  • Acute Hepatitis E Infection Accounts for Some Cases of Suspected Drug-Induced Liver Injury

    Timothy J. Davern;Naga Chalasani;Robert J. Fontana;Paul Hideyo Hayashi

  • The Size of the Viral Inoculum Contributes to the Outcome of Hepatitis B Virus Infection

    Shinichi Asabe;Stefan F. Wieland;Pratip K. Chattopadhyay;Mario Roederer

  • Hepatitis B virus DNA in the sera of HBsAg carriers: a marker of active hepatitis B virus replication in the liver.

    Ferruccio Bonino;Bill Hoyer;Judith Nelson;Ronald Engle

  • Cross-species infections of cultured cells by hepatitis E virus and discovery of an infectious virus–host recombinant

    Priyanka Shukla;Hanh T. Nguyen;Udana Torian;Ronald E. Engle

  • Epidemiology of Hepatitis E Virus in the United States: Results from the Third National Health and Nutrition Examination Survey, 1988–1994

    Mark H. Kuniholm;Robert H. Purcell;Geraldine M. McQuillan;Ronald E. Engle

  • Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees

    Jens Bukh;Thomas Pietschmann;Volker Lohmann;Nicole Krieger

  • Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1

    Jean-Christophe Meunier;Ronald E. Engle;Kristina Faulk;Ming Zhao

  • Adaptation of a Genotype 3 Hepatitis E Virus to Efficient Growth in Cell Culture Depends on an Inserted Human Gene Segment Acquired by Recombination

    P. Shukla;H. T. Nguyen;K. Faulk;K. Mather

  • Chimpanzees as an animal model for human norovirus infection and vaccine development

    Karin Bok;Gabriel I. Parra;Tanaji Mitra;Eugenio Abente

  • Time Trend of the Prevalence of Hepatitis E Antibodies among Farmers and Blood Donors: A Potential Zoonosis in Denmark

    Peer B. Christensen;Ronald E. Engle;Charlotte Hjort;Keld M. Homburg

  • Hepatitis B virus (HBV)/hepatitis D virus (HDV) coinfection in outbreaks of acute hepatitis in the Peruvian Amazon Basin : The roles of HDV genotype III and HBV genotype F

    Casey Jl;Niro Ga;Engle Re;Vega A

  • Prevalence of antibodies to the hepatitis E virus in pigs from countries where hepatitis E is common or is rare in the human population.

    Xiang Jin Meng;Serge Dea;Ronald E. Engle;Robert Friendship

  • Release of Genotype 1 Hepatitis E Virus from Cultured Hepatoma and Polarized Intestinal Cells Depends on Open Reading Frame 3 Protein and Requires an Intact PXXP Motif

    Suzanne U. Emerson;Hanh T. Nguyen;Udana Torian;Danielle Burke

  • High prevalence of hepatitis E antibodies in pregnant Egyptian women.

    Sonia K. Stoszek;Mohamed Abdel-Hamid;Mohamed Abdel-Hamid;Doa’a A. Saleh;Sherif El Kafrawy;Sherif El Kafrawy

Frequent Co-Authors

Robert H. Purcell
Robert H. Purcell National Institute of Allergy and Infectious Diseases
Suzanne U. Emerson
Suzanne U. Emerson National Institute of Allergy and Infectious Diseases
Sugantha Govindarajan
Sugantha Govindarajan University of Southern California
Jens Bukh
Jens Bukh University of Copenhagen
Patrizia Farci
Patrizia Farci National Institutes of Health
John L. Gerin
John L. Gerin Georgetown University Medical Center
Harvey J. Alter
Harvey J. Alter National Institutes of Health
David E. Kleiner
David E. Kleiner National Institutes of Health
Kenrad Edwin Nelson
Kenrad Edwin Nelson Johns Hopkins University
Xiang-Jin Meng
Xiang-Jin Meng Virginia Tech

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