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Molecular Biology

D-Index
56
Citations
20077
World Ranking
2181
National Ranking
145

Overview

Philipp Mertins is affiliated with the Max Delbrück Center for Molecular Medicine in Germany. Their research spans several interconnected fields within the life sciences, with a particular focus on molecular mechanisms underlying diseases and cellular function.

The primary fields of study in which Philipp Mertins has contributed include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broad categories, Mertins' work covers various subfields:

  • Molecular Biology
  • Immunology
  • Pulmonary and Respiratory Medicine
  • Oncology
  • Cardiology and Cardiovascular Medicine

The main topics addressed in their research feature:

  • Cystic Fibrosis Research Advances
  • Ubiquitin and Proteasome Pathways
  • Advanced Proteomics Techniques and Applications
  • RNA and Protein Synthesis Mechanisms
  • Protein Degradation and Inhibitors
  • Epigenetics and DNA Methylation
  • RNA Research and Splicing

Recent papers authored or co-authored by Philipp Mertins include:

  • Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy, 2020, Cell
  • Systems Analysis of RhoGEF and RhoGAP Regulatory Proteins Reveals Spatially Organized RAC1 Signalling from Integrin Adhesions, 2020, Nature Cell Biology
  • Longitudinal Effects of Elexacaftor/Tezacaftor/Ivacaftor on Sputum Viscoelastic Properties, Airway Infection and Inflammation in Patients with Cystic Fibrosis, 2023, European Respiratory Journal
  • Evolutionary Origins and Interactomes of Human, Young Microproteins and Small Peptides Translated from Short Open Reading Frames, 2023, Molecular Cell
  • Self-Sustaining IL-8 Loops Drive a Prothrombotic Neutrophil Phenotype in Severe COVID-19, 2021, JCI Insight

Mertins has frequently collaborated with several researchers in their field, including:

  • Marieluise Kirchner
  • Oliver Popp
  • Kerstin Fentker
  • Matthias Ziehm
  • Marcus Mall

The venues where their research has most often been published include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Cystic Fibrosis
  • Klinische Pädiatrie
  • Frontiers in Immunology

Best Publications

  • Proteogenomics connects somatic mutations to signalling in breast cancer

    Philipp Mertins;D. R. Mani;Kelly V. Ruggles;Michael A. Gillette;Michael A. Gillette

  • Proteogenomic characterization of human colon and rectal cancer

    Bing Zhang;Jing Wang;Xiaojing Wang;Jing Zhu

  • Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites

    Schraga Schwartz;Maxwell R. Mumbach;Marko Jovanovic;Tim Wang;Tim Wang

  • Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer

    Hui Zhang;Tao Liu;Zhen Zhang;Samuel H. Payne

  • High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis

    Schraga Schwartz;Sudeep D. Agarwala;Maxwell R. Mumbach;Marko Jovanovic

  • Integrated proteomic analysis of post-translational modifications by serial enrichment

    Philipp Mertins;Jana W Qiao;Jinal Patel;Namrata D Udeshi

  • Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities.

    Suhas Vasaikar;Chen Huang;Xiaojing Wang;Vladislav A. Petyuk

  • Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography-mass spectrometry

    Philipp Mertins;Philipp Mertins;Lauren C. Tang;Karsten Krug;David J. Clark

  • A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

    Oren Parnas;Marko Jovanovic;Thomas M. Eisenhaure;Thomas M. Eisenhaure;Rebecca H. Herbst;Rebecca H. Herbst

  • The Translational Landscape of the Human Heart

    Sebastiaan van Heesch;Franziska Witte;Valentin Schneider-Lunitz;Jana F. Schulz

  • Dynamic profiling of the protein life cycle in response to pathogens

    Marko Jovanovic;Michael S. Rooney;Philipp Mertins;Dariusz Przybylski

  • Transcriptional and Translational Differences of Microglia from Male and Female Brains.

    Dilansu Guneykaya;Andranik Ivanov;Daniel Perez Hernandez;Verena Haage

  • Refined Preparation and Use of Anti-diglycine Remnant (K-ε-GG) Antibody Enables Routine Quantification of 10,000s of Ubiquitination Sites in Single Proteomics Experiments

    Namrata D. Udeshi;Tanya Svinkina;Philipp Mertins;Eric Kuhn

  • Ischemia in Tumors Induces Early and Sustained Phosphorylation Changes in Stress Kinase Pathways but Does Not Affect Global Protein Levels

    Philipp Mertins;Feng Yang;Tao Liu;D. R. Mani

  • Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy.

    Karsten Krug;Eric J. Jaehnig;Shankha Satpathy;Lili Blumenberg

  • TMT Labeling for the Masses: A Robust and Cost-efficient, In-solution Labeling Approach.

    Jana Zecha;Shankha Satpathy;Tamara Kanashova;Shayan C. Avanessian

  • Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2

    Heidi Greulich;Bethany Kaplan;Philipp Mertins;Tzu-Hsiu Chen

  • Large-scale identification of ubiquitination sites by mass spectrometry

    Namrata D Udeshi;Philipp Mertins;Tanya Svinkina;Steven A Carr

  • A Curated Resource for Phosphosite-specific Signature Analysis

    Karsten Krug;Philipp Mertins;Philipp Mertins;Bin Zhang;Peter Hornbeck

  • A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

    Oren Parnas;Marko Jovanovic;Thomas M. Eisenhaure;Rebecca H. Herbst

Frequent Co-Authors

Steven A. Carr
Steven A. Carr Broad Institute
Nir Hacohen
Nir Hacohen Harvard University
Karl R. Clauser
Karl R. Clauser Broad Institute
Aviv Regev
Aviv Regev Genentech
Matthew J. Ellis
Matthew J. Ellis Baylor College of Medicine
Li Ding
Li Ding Washington University in St. Louis
David Fenyö
David Fenyö New York University
Benjamin L. Ebert
Benjamin L. Ebert Harvard University
Amanda G. Paulovich
Amanda G. Paulovich Fred Hutchinson Cancer Research Center
Bing Zhang
Bing Zhang Baylor College of Medicine

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