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Karl R. Clauser

Karl R. Clauser

D-Index & Metrics

Biology and Biochemistry

D-Index
80
Citations
30122
World Ranking
4011
National Ranking
1981

Overview

Karl R. Clauser is affiliated with the Broad Institute in the United States. Their research spans multiple disciplines within biochemistry, genetics, molecular biology, and medicine, with a significant focus on molecular biology and immunology among other subfields.

The scientist has contributed extensively to various aspects of cancer research, immunology, and proteomics. Main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

More detailed subfields in which Karl R. Clauser is active include:

  • Molecular Biology
  • Immunology
  • Oncology
  • Cancer Research
  • Spectroscopy

The primary topics of their work highlight a focus on immunotherapy, proteomics, and cancer-related molecular mechanisms. The topics researched are:

  • Vaccines and immunoinformatics approaches
  • Immunotherapy and Immune Responses
  • Advanced Proteomics Techniques and Applications
  • Peptidase Inhibition and Analysis
  • RNA modifications and cancer
  • Cancer Genomics and Diagnostics
  • Monoclonal and Polyclonal Antibodies Research

Karl R. Clauser has published papers in several frequent venues, illustrating their engagement with the broader scientific community. These venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell
  • Cancer Research
  • Nature Communications
  • Molecular & Cellular Proteomics

The scientist has contributed to important research papers such as:

  • Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma, 2020, Cell
  • Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy, 2020, Cell
  • Proteogenomic Characterization of Endometrial Carcinoma, 2020, Cell
  • Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma, 2021, Nature
  • A proteogenomic portrait of lung squamous cell carcinoma, 2021, Cell

Collaboration is a significant aspect of their work, with frequent co-authors including:

  • Steven A. Carr
  • Susan Klaeger
  • Jennifer G. Abelin
  • Gad Getz
  • Michael A. Gillette

Best Publications

  • Proteogenomics connects somatic mutations to signalling in breast cancer

    Philipp Mertins;D. R. Mani;Kelly V. Ruggles;Michael A. Gillette;Michael A. Gillette

  • Role of Accurate Mass Measurement (±10 ppm) in Protein Identification Strategies Employing MS or MS/MS and Database Searching

    Karl R. Clauser;Peter Baker;Alma L. Burlingame

  • MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins.

    Sarah E. Calvo;Sarah E. Calvo;Karl R. Clauser;Vamsi K. Mootha;Vamsi K. Mootha

  • Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule

    BC Cunningham;M Ultsch;AM De Vos;MG Mulkerrin

  • The Matrisome: In Silico Definition and In Vivo Characterization by Proteomics of Normal and Tumor Extracellular Matrices

    Alexandra Naba;Karl R. Clauser;Sebastian Hoersch;Sebastian Hoersch;Hui Liu

  • The extracellular matrix: Tools and insights for the "omics" era.

    Alexandra Naba;Karl R. Clauser;Huiming Ding;Charles A. Whittaker

  • De Novo Peptide Sequencing via Tandem Mass Spectrometry

    Vlado Dančík;Theresa A. Addona;Karl R. Clauser;James E. Vath

  • Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma

    Michael A. Gillette;Michael A. Gillette;Shankha Satpathy;Song Cao;Saravana M. Dhanasekaran

  • Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma.

    David J. Clark;Saravana M. Dhanasekaran;Francesca Petralia;Jianbo Pan

  • Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction.

    Jennifer G. Abelin;Derin B. Keskin;Siranush Sarkizova;Christina R. Hartigan

  • Repeatability and Reproducibility in Proteomic Identifications by Liquid Chromatography−Tandem Mass Spectrometry

    David L. Tabb;Lorenzo Vega-Montoto;Lorenzo Vega-Montoto;Paul A. Rudnick;Asokan Mulayath Variyath;Asokan Mulayath Variyath

  • Integrated proteomic analysis of post-translational modifications by serial enrichment

    Philipp Mertins;Jana W Qiao;Jinal Patel;Namrata D Udeshi

  • Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities.

    Suhas Vasaikar;Chen Huang;Xiaojing Wang;Vladislav A. Petyuk

  • The Need for Guidelines in Publication of Peptide and Protein Identification Data Working Group On Publication Guidelines For Peptide And Protein Identification Data

    Steven Carr;Ruedi Aebersold;Michael Baldwin;Al Burlingame

  • Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography-mass spectrometry

    Philipp Mertins;Philipp Mertins;Lauren C. Tang;Karsten Krug;David J. Clark

  • A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages

    Haihui Lu;Karl R. Clauser;Wai Leong Tam;Julia Fröse

  • Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters

    Alexandra Naba;Karl R. Clauser;John Michael Lamar;Steven A. Carr

  • A large peptidome dataset improves HLA class I epitope prediction across most of the human population.

    Siranush Sarkizova;Siranush Sarkizova;Susan Klaeger;Phuong M Le;Letitia W Li

  • Ischemia in Tumors Induces Early and Sustained Phosphorylation Changes in Stress Kinase Pathways but Does Not Affect Global Protein Levels

    Philipp Mertins;Feng Yang;Tao Liu;D. R. Mani

  • The extracellular matrix: Tools and insights for the “omics” era

    Karl R. Clauser;Steven A. Carr;Alexandra Naba;Huiming Ding

Frequent Co-Authors

Steven A. Carr
Steven A. Carr Broad Institute
Nir Hacohen
Nir Hacohen Harvard University
Philipp Mertins
Philipp Mertins Max Delbrück Center for Molecular Medicine
Matthew J. Ellis
Matthew J. Ellis Baylor College of Medicine
Henry Rodriguez
Henry Rodriguez National Institutes of Health
David Fenyö
David Fenyö New York University
Li Ding
Li Ding Washington University in St. Louis
Amanda G. Paulovich
Amanda G. Paulovich Fred Hutchinson Cancer Research Center
Todd R. Golub
Todd R. Golub Harvard University

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