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Genetics

D-Index
60
Citations
13932
World Ranking
3149
National Ranking
48

Research.com Recognitions

  • 2009 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Agricultural and Nutritional Sciences

Overview

Tosso Leeb is affiliated with the University of Bern in Switzerland. Their research spans a broad range of topics within biochemistry, genetics, and molecular biology, with significant contributions in medicine as well.

The primary fields of study for Tosso Leeb include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these areas, their work further specializes in subfields such as:

  • Molecular Biology
  • Genetics
  • Cell Biology
  • Neurology
  • Clinical Biochemistry

The main research topics Tosso Leeb has focused on are:

  • Skin and Cellular Biology Research
  • Wnt/β-catenin signaling in development and cancer
  • Neurological diseases and metabolism
  • Connective tissue disorders research
  • Metabolism and Genetic Disorders
  • Genetic and phenotypic traits in livestock
  • Genomics and Phylogenetic Studies

Tosso Leeb has contributed to multiple recent scientific papers. Selected publications include:

  • Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture, 2023, Genome Biology
  • Variants at the ASIP locus contribute to coat color darkening in Nellore cattle, 2021, Genetics Selection Evolution
  • Dog colour patterns explained by modular promoters of ancient canid origin, 2021, Nature Ecology & Evolution
  • Mutations in the Kinesin-2 Motor KIF3B Cause an Autosomal-Dominant Ciliopathy, 2020, The American Journal of Human Genetics
  • Dog10K_Boxer_Tasha_1.0: A Long-Read Assembly of the Dog Reference Genome, 2021, Genes

The scientist frequently publishes in the following venues:

  • Genes
  • Animal Genetics
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS ONE

Tosso Leeb often collaborates with a number of co-authors, including:

  • Vidhya Jagannathan
  • Matthias Christen
  • Sarah Kiener
  • Danika L. Bannasch
  • Monika Welle

They received recognition from the German National Academy of Sciences Leopoldina with an award in Agricultural and Nutritional Sciences in 2009.

Best Publications

  • Genome sequence, comparative analysis, and population genetics of the domestic horse.

    C. M. Wade;E. Giulotto;S. Sigurdsson;M. Zoli

  • FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome.

    Valentin Wucher;Fabrice Legeai;Benoît Hédan;Guillaume Rizk

  • Genome-Wide Analysis Reveals Selection for Important Traits in Domestic Horse Breeds

    Jessica L. Petersen;James R. Mickelson;Aaron K. Rendahl;Stephanie J. Valberg

  • Genetic diversity in the modern horse illustrated from genome-wide SNP data

    Jessica L. Petersen;James R. Mickelson;E. Gus Cothran;Lisa S. Andersson

  • A High Density SNP Array for the Domestic Horse and Extant Perissodactyla: Utility for Association Mapping, Genetic Diversity, and Phylogeny Studies

    Molly E. McCue;Danika L. Bannasch;Jessica Lynn Petersen;Jessica Gurr

  • Evolutionary Genomics and Conservation of the Endangered Przewalski's Horse.

    Clio Der Sarkissian;Luca Ermini;Mikkel Heide Schubert;Melinda A. Yang

  • Ancient genomic changes associated with domestication of the horse

    Pablo Librado;Cristina Gamba;Charleen Gaunitz;Clio Der Sarkissian

  • Serial translocation by means of circular intermediates underlies colour sidedness in cattle

    Keith Durkin;Wouter Coppieters;Cord Drögemüller;Naima Ahariz

  • A Genome-Wide Association Study Reveals Loci Influencing Height and Other Conformation Traits in Horses

    Heidi Signer-Hasler;Christine Flury;Bianca Haase;Bianca Haase;Dominik Burger

  • A Mutation in Hairless Dogs Implicates FOXI3 in Ectodermal Development

    Cord Drögemüller;Elinor K. Karlsson;Marjo K. Hytönen;Michele Perloski

  • Tracking the origins of Yakutian horses and the genetic basis for their fast adaptation to subarctic environments

    Pablo Librado;Clio Der Sarkissian;Luca Ermini;Mikkel Schubert

  • Analysis of sequence variability of the bovine prion protein gene (PRNP) in German cattle breeds

    Petra Sander;Henning Hamann;Ina Pfeiffer;Wilhelm Wemheuer

  • Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition.

    Christine Widmer;Jan M. Gebauer;Elena Brunstein;Sabrina Rosenbaum

  • Mutations in MITF and PAX3 Cause “Splashed White” and Other White Spotting Phenotypes in Horses

    Regula Hauswirth;Bianca Haase;Marlis Blatter;Samantha A. Brooks

  • The role of stallion seminal proteins in fertilisation.

    Edda Töpfer-Petersen;Mahnaz Ekhlasi-Hundrieser;Christiane Kirchhoff;Tosso Leeb

  • Allelic heterogeneity at the equine KIT locus in dominant white (W) horses.

    Bianca Haase;Samantha Ann Brooks;Angela Schlumbaum;Pedro Javier Azor;Pedro Javier Azor

  • Bovine prion protein gene (PRNP) promoter polymorphisms modulate PRNP expression and may be responsible for differences in bovine spongiform encephalopathy susceptibility.

    Petra Sander;Henning Hamann;Cord Drögemüller;Kseniya Kashkevich

  • A comprehensive biomedical variant catalogue based on whole genome sequences of 582 dogs and eight wolves.

    V. Jagannathan;C. Drögemüller;T. Leeb;Gustavo Aguirre

  • Evidence for a retroviral insertion in TRPM1 as the cause of congenital stationary night blindness and leopard complex spotting in the horse.

    Rebecca R. Bellone;Heather Holl;Vijayasaradhi Setaluri;Sulochana Devi

  • Chromosome Research : An International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology

    Keith Durkin;Nadine Cambisano;Naïma Ahariz;Corinne Fasquelle

Frequent Co-Authors

Hannes Lohi
Hannes Lohi University of Helsinki
Kerstin Lindblad-Toh
Kerstin Lindblad-Toh Uppsala University
James R. Mickelson
James R. Mickelson University of Minnesota
Jens Tetens
Jens Tetens University of Göttingen
Gottfried Brem
Gottfried Brem University of Veterinary Medicine Vienna
Molly E. McCue
Molly E. McCue University of Minnesota
Georg Thaller
Georg Thaller Kiel University
Bhanu P. Chowdhary
Bhanu P. Chowdhary Texas A&M University
Horst Hameister
Horst Hameister University of Ulm
Ludovic Orlando
Ludovic Orlando Paul Sabatier University

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