World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
50
Citations
7404
World Ranking
4276
National Ranking
1944

Overview

Brent E. Korba is affiliated with Georgetown University in the United States and has a research focus spanning multiple areas within medicine and molecular biology. Their scholarly output includes studies related to epidemiology, hepatology, physiology, and cancer research. The scientist's work has concentrated on several key topics such as liver disease diagnosis and treatment, Alzheimer's disease research and treatments, Hepatitis B Virus studies, liver diseases and immunity, endoplasmic reticulum stress and disease, dementia and cognitive impairment research, as well as bioinformatics and genomic networks.

Their recent published work includes the following papers:

  • Transcriptomics of MASLD Pathobiology in African American Patients in the Washington DC Area, 2023, International Journal of Molecular Sciences
  • Transcriptomic Analysis of Alzheimer's Disease Pathways in a Pakistani Population, 2024, Journal of Alzheimer s Disease Reports
  • Peroxisome Proliferator-Activated Receptor-α (PPARα) Expression in a Clinical Population of Pakistani Patients with Type 2 Diabetes and Dyslipidemia, 2022, International Journal of Molecular Sciences
  • Reshaping an Acyclic Nucleoside Phosphonate into a Selective Anti-hepatitis B Virus Compound, 2022, Journal of Medicinal Chemistry
  • Developing non-invasive molecular markers for early risk assessment of Alzheimer's disease, 2025, Biomarkers in Neuropsychiatry

The frequent co-authors collaborating with Brent E. Korba include:

  • Tanmoy Mondal
  • Christopher A. Loffredo
  • Somiranjan Ghosh
  • Gail Nunlee-Bland
  • Ruth Quartey

The main publication venues for Brent E. Korba's research are:

  • International Journal of Molecular Sciences
  • Journal of Alzheimer s Disease Reports
  • Journal of Medicinal Chemistry
  • Biomarkers in Neuropsychiatry
  • Journal of Hepatology

Brent E. Korba's body of work is grounded primarily in the fields of medicine and biochemistry, genetics, and molecular biology. Within these disciplines, subfields such as epidemiology and molecular biology have featured prominently in their research trajectory.

The scientist has contributed insights into complex diseases involving the liver and neurodegenerative conditions. Their investigations have addressed molecular pathways involved in Alzheimer's disease, as well as mechanisms related to Hepatitis B virus infection and liver pathology. The diversity of their research topics reflects a multi-disciplinary approach that integrates molecular techniques with clinical observations.

Overall, Brent E. Korba's research portfolio reveals sustained engagement with disease mechanisms at a molecular and clinical level, focusing on conditions with significant public health impact.

Best Publications

  • Handbook of Animal Models of Infection

    John D Morrey;R W Sidwell;B E Korba

  • Antiviral l-Nucleosides Specific for Hepatitis B Virus Infection

    Martin L. Bryant;Edward G. Bridges;Laurent Placidi;Abdesslem Faraj

  • Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication.

    Brent E. Korba;Abigail B. Montero;Kristine Farrar;Karen Gaye

  • Use of a standardized cell culture assay to assess activities of nucleoside analogs against hepatitis B virus replication.

    Brent E. Korba;John L. Gerin

  • Transformation of human bronchial epithelial cells transfected by Harvey ras oncogene

    George H. Yoakum;John F. Lechner;Edward W. Gabrielson;Brent E. Korba

  • Hepatocellular carcinoma in woodchuck hepatitis virus-infected woodchucks: presence of viral DNA in tumor tissue from chronic carriers and animals serologically recovered from acute infections.

    Brent E. Korba;Brent E. Korba;Frances V. Wells;Betty Baldwin;Paul J. Cote

  • Treatment of chronic hepadnavirus infection in a woodchuck animal model with an inhibitor of protein folding and trafficking.

    Timothy M. Block;Xuanyong Lu;Anand S. Mehta;Baruch S. Blumberg;Baruch S. Blumberg

  • Antiviral activity of clevudine [L‐FMAU, (1‐(2‐fluoro‐5‐methyl‐β, L‐arabinofuranosyl) uracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks (Marmota monax)

    Simon F. Peek;Paul J. Cote;James R. Jacob;Ilia A. Toshkov

  • Small-Molecule Effectors of Hepatitis B Virus Capsid Assembly Give Insight into Virus Life Cycle

    Christina Bourne;Sejin Lee;Bollu Venkataiah;Angela Lee

  • Hepatocellular carcinoma in the woodchuck model of hepatitis B virus infection

    Bud C. Tennant;Ilia A. Toshkov;Simon F. Peek;James R. Jacob

  • Effects of age and viral determinants on chronicity as an outcome of experimental woodchuck hepatitis virus infection

    Paul J. Cote;Brent E. Korba;Roger H. Miller;James R. Jacob

  • A cell culture assay for compounds which inhibit hepatitis B virus replication.

    Brent E. Korba;Gregory Milman

  • Hepadnavirus infection of peripheral blood lymphocytes in vivo: woodchuck and chimpanzee models of viral hepatitis.

    B E Korba;F Wells;B C Tennant;G H Yoakum

  • Treatment of chronic woodchuck hepatitis virus infection in the eastern woodchuck (marmota monax) with nucleoside analogues is predictive of therapy for chronic hepatitis B virus infection in humans

    Brent E. Korba;Paul Cote;William Hornbuckle;Bud C. Tennant

  • Pure nucleoside enantiomers of beta-2',3'-dideoxycytidine analogs are selective inhibitors of hepatitis B virus in vitro.

    R. F. Schinazi;G. Gosselin;Abdesslem Faraj;B. E. Korba

  • Evaluation of Hexadecyloxypropyl-9-R-[2-(Phosphonomethoxy)Propyl]-Adenine, CMX157, as a Potential Treatment for Human Immunodeficiency Virus Type 1 and Hepatitis B Virus Infections

    George R. Painter;Merrick R. Almond;Lawrence C. Trost;Bernhard M. Lampert

  • Penciclovir is a selective inhibitor of hepatitis B virus replication in cultured human hepatoblastoma cells.

    B E Korba;M R Boyd

  • In vitro evaluation of combination therapies against hepatitis B virus replication

    Brent E. Korba

  • Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection.

    Bud C. Tennant;Betty H. Baldwin;Lou Ann Graham;Mary A. Ascenzi

  • Immunization with Surface Antigen Vaccine Alone and after Treatment with 1-(2-Fluoro-5-Methyl-β-l-Arabinofuranosyl)-Uracil (l-FMAU) Breaks Humoral and Cell-Mediated Immune Tolerance in Chronic Woodchuck Hepatitis Virus Infection

    Stephan Menne;Carol A. Roneker;Brent E. Korba;John L. Gerin

  • Anti-Hepatitis B Virus Activity of ORI-9020, a Novel Phosphorothioate Dinucleotide, in a Transgenic Mouse Model

    Radhakrishnan P. Iyer;Arlene Roland;Yi Jin;Samir Mounir

Frequent Co-Authors

Bud C. Tennant
Bud C. Tennant Cornell University
Paul J. Cote
Paul J. Cote Georgetown University Medical Center
John L. Gerin
John L. Gerin Georgetown University Medical Center
Raymond F. Schinazi
Raymond F. Schinazi Emory University
John D. Morrey
John D. Morrey Utah State University
Karl Y. Hostetler
Karl Y. Hostetler University of California, San Diego
Chung K. Chu
Chung K. Chu University of Georgia
Robert H. Purcell
Robert H. Purcell National Institute of Allergy and Infectious Diseases
Robert W. Sidwell
Robert W. Sidwell Utah State University
Tarek S. Mansour
Tarek S. Mansour Pfizer (United States)

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