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Karl Y. Hostetler

D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
12922
World Ranking
7578
National Ranking
3443

Karl Y. Hostetler publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Karl Y. Hostetler sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 254 publications — 68th percentile

68% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Karl Y. Hostetler D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Karl Y. Hostetler sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 69 D-Index — 63rd percentile

63% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 1980 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Karl Y. Hostetler is affiliated with the University of California, San Diego in the United States. Their research primarily focuses on medicine, with a particular emphasis on infectious diseases, epidemiology, oncology, cardiology and cardiovascular medicine, and genetics.

The scientist's work covers a range of topics including COVID-19 clinical research studies, SARS-CoV-2 and COVID-19 research, respiratory viral infections research, PARP inhibition in cancer therapy, viral infections and immunology research, virus-based gene therapy research, and cytomegalovirus and herpesvirus research.

Recent papers authored or coauthored by Karl Y. Hostetler include:

  • Rethinking Remdesivir: Synthesis, Antiviral Activity, and Pharmacokinetics of Oral Lipid Prodrugs (2021, Antimicrobial Agents and Chemotherapy)
  • Broad-Spectrum In Vitro Antiviral Activity of ODBG-P-RVn: An Orally-Available, Lipid-Modified Monophosphate Prodrug of Remdesivir Parent Nucleoside (GS-441524) (2021, Microbiology Spectrum)
  • Rethinking Remdesivir: Synthesis, Antiviral Activity and Pharmacokinetics of Oral Lipid Prodrugs (2020, bioRxiv (Cold Spring Harbor Laboratory))
  • 1-O-Octadecyl-2-O-benzyl-sn-glyceryl-3-phospho-GS-441524 (V2043). Evaluation of Oral V2043 in a Mouse Model of SARS-CoV-2 Infection and Synthesis and Antiviral Evaluation of Additional Phospholipid Esters with Enhanced Anti-SARS-CoV-2 Activity (2023, Journal of Medicinal Chemistry)
  • Enhanced broad spectrum in vitro antiviral efficacy of 3-F-4-MeO-Bn, 3-CN, and 4-CN derivatives of lipid remdesivir nucleoside monophosphate prodrugs (2023, Antiviral Research)

Frequent coauthors of Karl Y. Hostetler include:

  • Robert T. Schooley
  • James R. Beadle
  • Nadejda Valiaeva
  • Joyce Murphy
  • Aaron F. Carlin

The scientist's research has been predominantly published in these venues:

  • Antimicrobial Agents and Chemotherapy
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Microbiology Spectrum
  • Journal of Medicinal Chemistry
  • Antiviral Research

Karl Y. Hostetler was recognized as a Fellow of the John Simon Guggenheim Memorial Foundation in 1980.

Best Publications

  • An improved two dimensional thin-layer chromatography system for the separation of phosphatidylglycerol and its derivatives

    B. J. H. M. Poorthuis;B. J. H. M. Poorthuis;Paul J. Yazaki;Paul J. Yazaki;Karl Y. Hostetler;Karl Y. Hostetler

  • Alkoxyalkyl prodrugs of acyclic nucleoside phosphonates enhance oral antiviral activity and reduce toxicity: current state of the art

    Karl Y. Hostetler

  • LIPID DERIVATIVES OF ANTIVIRAL NUCLEOSIDE ANALOGUES, LIPOSOMES THEREOF AND PHARMACEUTICAL USE

    Hostetler Karl Y;Raj Kumar;Stuhmiller Louise M

  • Synthesis and antiretroviral activity of phospholipid analogs of azidothymidine and other antiviral nucleosides.

    K. Y. Hostetler;L. M. Stuhmiller;H. B. M. Lenting;H. Van Den Bosch

  • Enhanced inhibition of orthopoxvirus replication in vitro by alkoxyalkyl esters of cidofovir and cyclic cidofovir.

    Earl R. Kern;Caroll Hartline;Emma Harden;Kathy Keith

  • Lipid derivatives of phosphonoacids for liposomal incorporation and method of use

    Karl Y. Hostetler;Raj Kumar

  • Alkoxyalkyl Esters of Cidofovir and Cyclic Cidofovir Exhibit Multiple-Log Enhancement of Antiviral Activity against Cytomegalovirus and Herpesvirus Replication In Vitro

    James R. Beadle;Caroll Hartline;Kathy A. Aldern;Natalie Rodriguez

  • Esterification of cidofovir with alkoxyalkanols increases oral bioavailability and diminishes drug accumulation in kidney

    Stephanie L Ciesla;Julissa Trahan;W.Brad Wan;James R Beadle

  • Mitochondrial cardiolipin in diverse eukaryotes. Comparison of biosynthetic reactions and molecular acyl species.

    Michael Schlame;Stuart Brody;Karl Y. Hostetler

  • Inhibition of lysosomal phospholipase A and phospholipase C by chloroquine and 4,4'-bis(diethylaminoethoxy) alpha, beta-diethyldiphenylethane.

    Y Matsuzawa;K Y Hostetler

  • Oral Treatment of Cowpox and Vaccinia Virus Infections in Mice with Ether Lipid Esters of Cidofovir

    Debra C. Quenelle;Deborah J. Collins;W. Brad Wan;James R. Beadle

  • Lipid derivatives of antiviral nucleosides, liposomal incorporation and method of use.

    Karl Y. Hostetler;Raj Kumar;Louise M. Stuhmiller

  • Ether Lipid-Ester Prodrugs of Acyclic Nucleoside Phosphonates: Activity against Adenovirus Replication In Vitro

    Caroll B. Hartline;Kortney M. Gustin;William B. Wan;Stephanie L. Ciesla

  • Efficacy of oral active ether lipid analogs of cidofovir in a lethal mousepox model

    R.Mark Buller;Gelita Owens;Jill Schriewer;Lora Melman

  • Increased Antiviral Activity of 1-O-Hexadecyloxypropyl-[2-14C]cidofovir in MRC-5 Human Lung Fibroblasts Is Explained by Unique Cellular Uptake and Metabolism

    Kathy A. Aldern;Stephanie L. Ciesla;Kristine L. Winegarden;Karl Y. Hostetler

  • Mechanism of Inhibition of Vaccinia Virus DNA Polymerase by Cidofovir Diphosphate

    Wendy C. Magee;Karl Y. Hostetler;David H. Evans

  • Properties of phospholipase C isolated from rat liver lysosomes.

    Y Matsuzawa;K Y Hostetler

  • Biosynthesis of cardiolipin in liver mitochondria.

    Karl Y. Hostetler;H. van Den Bosch;L.L.M. van Deenen

  • SUBCELLULAR AND SUBMITOCHONDRIAL LOCALIZATION OF THE BIOSYNTHESIS OF CARDIOLIPIN AND RELATED PHOSPHOLIPIDS IN RAT LIVER

    K.Y. Hostetler;H.Van Den Bosch

  • Comparative Activities of Lipid Esters of Cidofovir and Cyclic Cidofovir against Replication of Herpesviruses In Vitro

    Stephanie L. Williams-Aziz;Caroll B. Hartline;Emma A. Harden;Shannon L. Daily

Frequent Co-Authors

William R. Freeman
William R. Freeman University of California, San Diego
Douglas D. Richman
Douglas D. Richman University of California, San Diego
Earl R. Kern
Earl R. Kern University of Alabama
H. van den Bosch
H. van den Bosch Utrecht University
Brent E. Korba
Brent E. Korba Georgetown University
Robert T. Schooley
Robert T. Schooley University of California, San Diego
Bernard R. Landau
Bernard R. Landau Case Western Reserve University
Erik De Clercq
Erik De Clercq Rega Institute for Medical Research
Yuji Matsuzawa
Yuji Matsuzawa Sumitomo Hospital
John W. Mellors
John W. Mellors University of Pittsburgh

External Links

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Publications: 28

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